(53 nodes) Recycling endosome membrane network (Oryzias melastigma)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC112150497	RAB11B, member RAS oncogene family, a. (265 aa)
	LOC112150496	RAB11B, member RAS oncogene family, b. (218 aa)
	LOC112150086	Secretory carrier-associated membrane protein. (233 aa)
	neu3	Sialidase 3 (membrane sialidase), tandem duplicate 1. (410 aa)
	EHD2	EH-domain containing 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (540 aa)
	LOC112153495	RAP2C, member of RAS oncogene family. (183 aa)
	SCAMP1-2	Secretory carrier-associated membrane protein. (346 aa)
	ENSOMEP00000033364	EH-domain containing 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (532 aa)
	LAMP5	Lysosomal associated membrane protein family member 5. (270 aa)
	LOC112136661	RAB11a, member RAS oncogene family, like. (216 aa)
	ENSOMEP00000035420	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (163 aa)
	LOC112147186	Uncharacterized protein. (218 aa)
	rab11a	RAB11a, member RAS oncogene family. (215 aa)
	SCAMP1	Secretory carrier-associated membrane protein. (341 aa)
	LOC112154584	RAB11 family interacting protein 3 (class II). (1055 aa)
	LOC112152525	Secretory carrier-associated membrane protein. (230 aa)
	ENSOMEP00000012532	Uncharacterized protein. (145 aa)
	ENSOMEP00000012521	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b. (675 aa)
	atg9a	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (848 aa)
	ENSOMEP00000011463	Uncharacterized protein. (73 aa)
	ENSOMEP00000009897	ADP-ribosylation factor 6a. (118 aa)
	ENSOMEP00000008451	Zinc finger, FYVE domain containing 27. (350 aa)
	rab13	RAB13, member RAS oncogene family. (207 aa)
	lztr1	Leucine-zipper-like transcription regulator 1. (780 aa)
	gripap1	GRIP1 associated protein 1. (885 aa)
	vti1b	Vesicle transport through interaction with t-SNAREs 1B. (227 aa)
	LOC112139362	MARVEL domain-containing protein. (182 aa)
	ENSOMEP00000019560	Sortilin-related receptor, L(DLR class) A repeats containing. (2096 aa)
	LOC112146313	EH-domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (546 aa)
	LOC112147450	Peptidase_S9 domain-containing protein. (351 aa)
	LOC112157898	EH-domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
	LOC112157507	Two pore segment channel 3. (771 aa)
	pdlim4	PDZ and LIM domain 4. (368 aa)
	LOC112157433	Golgi associated, gamma adaptin ear containing, ARF binding protein 3a. (735 aa)
	slc1a1	Amino acid transporter. (524 aa)
	RAP2A	RAP2A, member of RAS oncogene family. (183 aa)
	cftr	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1502 aa)
	ENSOMEP00000025337	BMERB domain-containing protein. (555 aa)
	ENSOMEP00000032149	RAB11 family interacting protein 4 (class II) b. (505 aa)
	scamp3	Secretory carrier-associated membrane protein. (334 aa)
	ENSOMEP00000025779	Secretory carrier-associated membrane protein. (328 aa)
	LOC112160809	Secretory carrier-associated membrane protein. (227 aa)
	LOC112141260	Secretory carrier-associated membrane protein. (333 aa)
	ENSOMEP00000028995	RAB11 family interacting protein 4 (class II) a. (593 aa)
	abhd17b	Abhydrolase domain containing 17B. (288 aa)
	LOC112147470	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (809 aa)
	rab12	RAB12, member RAS oncogene family. (242 aa)
	ENSOMEP00000006104	Uncharacterized protein. (110 aa)
	washc1	WAS protein family homolog 1. (474 aa)
	LOC112150829	Abhydrolase domain containing 17A. (319 aa)
	rab4a	RAB4a, member RAS oncogene family. (213 aa)
	LOC112149846	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (545 aa)
	tpcn1	Two pore segment channel 1. (822 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EHD2	ENSOMEP00000025337	ENSOMEP00000000370	ENSOMEP00000025337	EH-domain containing 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	BMERB domain-containing protein.	0.773
EHD2	LOC112149846	ENSOMEP00000000370	ENSOMEP00000003058	EH-domain containing 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.926
ENSOMEP00000009897	ENSOMEP00000012521	ENSOMEP00000009897	ENSOMEP00000012521	ADP-ribosylation factor 6a.	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b.	0.899
ENSOMEP00000009897	ENSOMEP00000028995	ENSOMEP00000009897	ENSOMEP00000028995	ADP-ribosylation factor 6a.	RAB11 family interacting protein 4 (class II) a.	0.612
ENSOMEP00000009897	ENSOMEP00000032149	ENSOMEP00000009897	ENSOMEP00000032149	ADP-ribosylation factor 6a.	RAB11 family interacting protein 4 (class II) b.	0.612
ENSOMEP00000009897	LOC112154584	ENSOMEP00000009897	ENSOMEP00000015019	ADP-ribosylation factor 6a.	RAB11 family interacting protein 3 (class II).	0.612
ENSOMEP00000009897	LOC112157433	ENSOMEP00000009897	ENSOMEP00000016558	ADP-ribosylation factor 6a.	Golgi associated, gamma adaptin ear containing, ARF binding protein 3a.	0.899
ENSOMEP00000009897	rab4a	ENSOMEP00000009897	ENSOMEP00000004549	ADP-ribosylation factor 6a.	RAB4a, member RAS oncogene family.	0.546
ENSOMEP00000011463	ENSOMEP00000019560	ENSOMEP00000011463	ENSOMEP00000019560	Uncharacterized protein.	Sortilin-related receptor, L(DLR class) A repeats containing.	0.441
ENSOMEP00000011463	ENSOMEP00000028995	ENSOMEP00000011463	ENSOMEP00000028995	Uncharacterized protein.	RAB11 family interacting protein 4 (class II) a.	0.869
ENSOMEP00000011463	ENSOMEP00000032149	ENSOMEP00000011463	ENSOMEP00000032149	Uncharacterized protein.	RAB11 family interacting protein 4 (class II) b.	0.869
ENSOMEP00000011463	LOC112154584	ENSOMEP00000011463	ENSOMEP00000015019	Uncharacterized protein.	RAB11 family interacting protein 3 (class II).	0.869
ENSOMEP00000011463	rab12	ENSOMEP00000011463	ENSOMEP00000007108	Uncharacterized protein.	RAB12, member RAS oncogene family.	0.450
ENSOMEP00000011463	rab13	ENSOMEP00000011463	ENSOMEP00000007130	Uncharacterized protein.	RAB13, member RAS oncogene family.	0.592
ENSOMEP00000012521	ENSOMEP00000009897	ENSOMEP00000012521	ENSOMEP00000009897	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b.	ADP-ribosylation factor 6a.	0.899
ENSOMEP00000012521	ENSOMEP00000035420	ENSOMEP00000012521	ENSOMEP00000035420	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.899
ENSOMEP00000012521	rab4a	ENSOMEP00000012521	ENSOMEP00000004549	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b.	RAB4a, member RAS oncogene family.	0.601
ENSOMEP00000012532	ENSOMEP00000028995	ENSOMEP00000012532	ENSOMEP00000028995	Uncharacterized protein.	RAB11 family interacting protein 4 (class II) a.	0.496
ENSOMEP00000012532	ENSOMEP00000032149	ENSOMEP00000012532	ENSOMEP00000032149	Uncharacterized protein.	RAB11 family interacting protein 4 (class II) b.	0.496
ENSOMEP00000012532	LOC112154584	ENSOMEP00000012532	ENSOMEP00000015019	Uncharacterized protein.	RAB11 family interacting protein 3 (class II).	0.496