(45 nodes) Negative regulation of extrinsic apoptotic signaling pathway network (Oryzias melastigma)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC112144544	GATA binding protein 1a. (416 aa)
	ENSOMEP00000000292	Baculoviral IAP repeat containing 6. (4149 aa)
	cflar	Uncharacterized protein; Belongs to the peptidase C14A family. (464 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (630 aa)
	sfrp2	Secreted frizzled-related protein 2. (290 aa)
	LOC112163435	Ring finger protein 34b. (407 aa)
	LOC112148999	Uncharacterized protein. (336 aa)
	ENSOMEP00000002155	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (394 aa)
	ENSOMEP00000003330	RING-type domain-containing protein. (841 aa)
	psme3	Proteasome activator subunit 3. (256 aa)
	eya3	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (574 aa)
	LOC112139901	Androgen receptor. (718 aa)
	itprip	Inositol 1,4,5-trisphosphate receptor interacting protein. (533 aa)
	rb1cc1	RB1-inducible coiled-coil 1. (1601 aa)
	LOC112139461	Tumor necrosis factor a (TNF superfamily, member 2). (236 aa)
	ENSOMEP00000007480	PX domain-containing protein. (57 aa)
	ENSOMEP00000007491	Serum/glucocorticoid regulated kinase family member 3. (419 aa)
	faim	Fas apoptotic inhibitory molecule a. (197 aa)
	LOC112148302	Interleukin-1. (244 aa)
	ENSOMEP00000009575	Si:dkeyp-80c12.4. (631 aa)
	ENSOMEP00000010146	Tumor necrosis factor, alpha-induced protein 3. (856 aa)
	src	Tyrosine-protein kinase. (550 aa)
	LOC112153467	Uncharacterized protein. (678 aa)
	LOC112158705	Tyrosine-protein kinase. (551 aa)
	LOC112156830	Fas apoptotic inhibitory molecule b. (181 aa)
	zmynd11	Zinc finger, MYND-type containing 11. (648 aa)
	ENSOMEP00000017455	Uncharacterized protein. (575 aa)
	ENSOMEP00000017766	Galectin. (274 aa)
	ENSOMEP00000018249	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (92 aa)
	LOC112141640	Zinc finger, C3HC-type containing 1. (496 aa)
	ENSOMEP00000020141	Uncharacterized protein. (424 aa)
	unc5b	Unc-5 netrin receptor B. (945 aa)
	LOC112147081	Secretogranin II (chromogranin C), b. (597 aa)
	LOC112148464	Galectin. (371 aa)
	zc3hc1	Zinc finger, C3HC-type containing 1. (496 aa)
	map2k5	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (436 aa)
	gclm	Glutamate-cysteine ligase, modifier subunit. (271 aa)
	ENSOMEP00000029380	Ring finger protein 34a. (394 aa)
	ENSOMEP00000029865	Growth arrest-specific 1a. (264 aa)
	ENSOMEP00000030642	Growth arrest-specific 1b. (242 aa)
	ENSOMEP00000032318	Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase. (428 aa)
	ENSOMEP00000033245	Proliferation and apoptosis adaptor protein 15. (138 aa)
	ENSOMEP00000033614	UBIQUITIN_CONJUGAT_2 domain-containing protein. (176 aa)
	LOC112145350	Galectin. (292 aa)
	fgb	Fibrinogen beta chain. (498 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000000292	ENSOMEP00000003330	ENSOMEP00000000292	ENSOMEP00000003330	Baculoviral IAP repeat containing 6.	RING-type domain-containing protein.	0.582
ENSOMEP00000000292	ENSOMEP00000010146	ENSOMEP00000000292	ENSOMEP00000010146	Baculoviral IAP repeat containing 6.	Tumor necrosis factor, alpha-induced protein 3.	0.532
ENSOMEP00000000292	ENSOMEP00000018249	ENSOMEP00000000292	ENSOMEP00000018249	Baculoviral IAP repeat containing 6.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.791
ENSOMEP00000000292	ENSOMEP00000033245	ENSOMEP00000000292	ENSOMEP00000033245	Baculoviral IAP repeat containing 6.	Proliferation and apoptosis adaptor protein 15.	0.808
ENSOMEP00000000292	ENSOMEP00000033614	ENSOMEP00000000292	ENSOMEP00000033614	Baculoviral IAP repeat containing 6.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.989
ENSOMEP00000000292	LOC112139461	ENSOMEP00000000292	ENSOMEP00000006947	Baculoviral IAP repeat containing 6.	Tumor necrosis factor a (TNF superfamily, member 2).	0.791
ENSOMEP00000000292	LOC112158705	ENSOMEP00000000292	ENSOMEP00000015391	Baculoviral IAP repeat containing 6.	Tyrosine-protein kinase.	0.626
ENSOMEP00000000292	cflar	ENSOMEP00000000292	ENSOMEP00000000784	Baculoviral IAP repeat containing 6.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.831
ENSOMEP00000000292	psme3	ENSOMEP00000000292	ENSOMEP00000003438	Baculoviral IAP repeat containing 6.	Proteasome activator subunit 3.	0.680
ENSOMEP00000000292	src	ENSOMEP00000000292	ENSOMEP00000012169	Baculoviral IAP repeat containing 6.	Tyrosine-protein kinase.	0.626
ENSOMEP00000002155	fgb	ENSOMEP00000002155	ENSOMEP00000035392	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	Fibrinogen beta chain.	0.623
ENSOMEP00000003330	ENSOMEP00000000292	ENSOMEP00000003330	ENSOMEP00000000292	RING-type domain-containing protein.	Baculoviral IAP repeat containing 6.	0.582
ENSOMEP00000003330	ENSOMEP00000033614	ENSOMEP00000003330	ENSOMEP00000033614	RING-type domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.582
ENSOMEP00000003330	LOC112139901	ENSOMEP00000003330	ENSOMEP00000004685	RING-type domain-containing protein.	Androgen receptor.	0.589
ENSOMEP00000003330	LOC112153467	ENSOMEP00000003330	ENSOMEP00000012388	RING-type domain-containing protein.	Uncharacterized protein.	0.672
ENSOMEP00000007480	ENSOMEP00000007491	ENSOMEP00000007480	ENSOMEP00000007491	PX domain-containing protein.	Serum/glucocorticoid regulated kinase family member 3.	0.709
ENSOMEP00000007480	LOC112158705	ENSOMEP00000007480	ENSOMEP00000015391	PX domain-containing protein.	Tyrosine-protein kinase.	0.512
ENSOMEP00000007480	src	ENSOMEP00000007480	ENSOMEP00000012169	PX domain-containing protein.	Tyrosine-protein kinase.	0.512
ENSOMEP00000007491	ENSOMEP00000007480	ENSOMEP00000007491	ENSOMEP00000007480	Serum/glucocorticoid regulated kinase family member 3.	PX domain-containing protein.	0.709
ENSOMEP00000007491	LOC112158705	ENSOMEP00000007491	ENSOMEP00000015391	Serum/glucocorticoid regulated kinase family member 3.	Tyrosine-protein kinase.	0.512