106 items (Oryzias melastigma) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC112153304	CD40 ligand; Belongs to the tumor necrosis factor family. (237 aa)
	LOC112159050	Extracellular sulfatase. (869 aa)
	LOC112144907	Transforming growth factor, alpha. (237 aa)
	wnt2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	fzd6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (680 aa)
	ENSOMEP00000024195	Uncharacterized protein. (484 aa)
	LOC112145552	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (199 aa)
	LOC112145370	Uncharacterized protein. (224 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (525 aa)
	cpm	Carboxypeptidase M. (456 aa)
	ENSOMEP00000008735	Ig-like domain-containing protein. (341 aa)
	ENSOMEP00000008947	Ig-like domain-containing protein. (267 aa)
	ENSOMEP00000009191	Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (215 aa)
	LOC112145219	Uncharacterized protein. (328 aa)
	LOC112149240	Purinergic receptor P2Y12. (355 aa)
	ENSOMEP00000010491	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (679 aa)
	LOC112143254	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (259 aa)
	LOC112143691	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
	ENSOMEP00000031391	Fibroblast growth factor 10b; Belongs to the heparin-binding growth factors family. (70 aa)
	ENSOMEP00000031253	Reverse transcriptase domain-containing protein. (1094 aa)
	cd59	UPAR/Ly6 domain-containing protein. (117 aa)
	ENSOMEP00000026367	Uncharacterized protein. (312 aa)
	fgf22	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	LOC112155093	Ig-like domain-containing protein. (307 aa)
	ENSOMEP00000026783	MPL proto-oncogene, thrombopoietin receptor. (646 aa)
	LOC112159951	Ig-like domain-containing protein. (282 aa)
	ENSOMEP00000000089	Sulfatase 2a. (855 aa)
	LOC112144659	Zgc:92107. (1127 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (405 aa)
	TMX3	Thioredoxin related transmembrane protein 3. (481 aa)
	LOC112148434	Uncharacterized protein. (359 aa)
	ENSOMEP00000000731	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
	LOC112141019	Leucine rich repeat containing 32. (677 aa)
	LOC112144329	Thioredoxin domain-containing protein. (427 aa)
	LOC112149905	Folate receptor. (242 aa)
	LOC112144176	Teratocarcinoma-derived growth factor 1. (198 aa)
	LOC112157702	ADAM metallopeptidase domain 17b. (838 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1330 aa)
	ENSOMEP00000003842	Reverse transcriptase domain-containing protein. (173 aa)
	LOC112146315	Lysophosphatidic acid receptor 2a. (368 aa)
	ENSOMEP00000005032	Semaphorin 7A; Belongs to the semaphorin family. (350 aa)
	ENSOMEP00000005920	Ig-like domain-containing protein. (246 aa)
	LOC112155560	Ig-like domain-containing protein. (880 aa)
	ENSOMEP00000006463	Reverse transcriptase domain-containing protein. (938 aa)
	ackr3	Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family. (379 aa)
	LOC112149788	ADAM metallopeptidase domain 17a. (863 aa)
	LOC112153650	Uncharacterized protein. (653 aa)
	LOC112146967	Zgc:109949. (275 aa)
	ENSOMEP00000008125	Ig-like domain-containing protein. (216 aa)
	sulf1	Sulfatase 1. (1141 aa)
	LOC112152992	Heparin-binding EGF-like growth factor a. (236 aa)
	ccr6	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	cd226	CD226 molecule. (315 aa)
	FZD3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (760 aa)
	rtn4r	Reticulon 4 receptor. (467 aa)
	ENSOMEP00000028760	Reverse transcriptase domain-containing protein. (557 aa)
	LOC112153744	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (336 aa)
	LOC112153646	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
	ENSOMEP00000029878	Reverse transcriptase domain-containing protein. (496 aa)
	LOC112143674	Ig-like domain-containing protein. (484 aa)
	ENSOMEP00000013121	Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	srpx2	Sushi-repeat containing protein X-linked 2. (455 aa)
	ENSOMEP00000013910	Uncharacterized protein. (369 aa)
	igsf21	Immunoglobin superfamily, member 21a. (492 aa)
	LOC112159194	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
	intu	Inturned planar cell polarity protein. (957 aa)
	LOC112138061	Ig-like domain-containing protein. (238 aa)
	nrros	Negative regulator of reactive oxygen species. (682 aa)
	hpn	Hepsin; Belongs to the peptidase S1 family. (427 aa)
	LOC112137135	Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (210 aa)
	LOC112137124	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (367 aa)
	LOC112136554	Si:ch211-113g11.6; Belongs to the semaphorin family. (638 aa)
	ENSOMEP00000016487	Ig-like domain-containing protein. (137 aa)
	ENSOMEP00000016511	Ig-like domain-containing protein. (142 aa)
	LOC112141087	Leukotriene B4 receptor 2a. (369 aa)
	ENSOMEP00000017566	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (440 aa)
	LOC112138619	Chemokine (C-C motif) receptor 6b; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	lpar1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (390 aa)
	EFNA5	Ephrin A5; Belongs to the ephrin family. (229 aa)
	ENSOMEP00000030148	G_PROTEIN_RECEP_F1_2 domain-containing protein. (190 aa)
	ENSOMEP00000030236	Ig-like domain-containing protein. (193 aa)
	ENSOMEP00000030292	Uncharacterized protein. (4302 aa)
	ENSOMEP00000030337	Uncharacterized protein. (262 aa)
	fzd3	Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family. (695 aa)
	ENSOMEP00000030911	Uncharacterized protein. (542 aa)
	ca6	Carbonic anhydrase VI; Belongs to the alpha-carbonic anhydrase family. (607 aa)
	ENSOMEP00000019885	Immunoglobin superfamily, member 21b. (462 aa)
	LOC112152745	Semaphorin 7A; Belongs to the semaphorin family. (648 aa)
	ENSOMEP00000020475	Signal peptide, CUB domain, EGF-like 2. (979 aa)
	ENSOMEP00000020492	FZ domain-containing protein. (95 aa)
	ENSOMEP00000020507	FZ domain-containing protein. (110 aa)
	ENSOMEP00000021008	Leukotriene B4 receptor 2b. (370 aa)
	ENSOMEP00000036009	ZP domain-containing protein. (479 aa)
	ENSOMEP00000035571	Uncharacterized protein. (95 aa)
	ENSOMEP00000035226	FZ domain-containing protein. (93 aa)
	nccrp1	Non-specific cytotoxic cell receptor protein 1. (233 aa)
	mif	Macrophage migration inhibitory factor. (115 aa)
	LOC112159623	Uncharacterized protein. (301 aa)
	ENSOMEP00000033964	G_PROTEIN_RECEP_F1_2 domain-containing protein. (137 aa)
	ENSOMEP00000033429	Uncharacterized protein. (96 aa)
	LOC112161149	Uncharacterized protein; Belongs to the semaphorin family. (622 aa)
	LOC112141076	Leukotriene B4 receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	LOC112136134	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (229 aa)
	LOC112144558	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
	sigirr	Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain. (520 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000000731	LOC112143254	ENSOMEP00000000731	ENSOMEP00000010529	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.454
ENSOMEP00000000731	LOC112145552	ENSOMEP00000000731	ENSOMEP00000023458	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.454
ENSOMEP00000003842	ENSOMEP00000026367	ENSOMEP00000003842	ENSOMEP00000026367	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.855
ENSOMEP00000005920	LOC112155093	ENSOMEP00000005920	ENSOMEP00000026625	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.426
ENSOMEP00000006463	ENSOMEP00000026367	ENSOMEP00000006463	ENSOMEP00000026367	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.788
ENSOMEP00000008735	ENSOMEP00000024195	ENSOMEP00000008735	ENSOMEP00000024195	Ig-like domain-containing protein.	Uncharacterized protein.	0.437
ENSOMEP00000008947	LOC112143674	ENSOMEP00000008947	ENSOMEP00000012790	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.459
ENSOMEP00000008947	LOC112155093	ENSOMEP00000008947	ENSOMEP00000026625	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.976
ENSOMEP00000008947	ptprc	ENSOMEP00000008947	ENSOMEP00000003822	Ig-like domain-containing protein.	Protein tyrosine phosphatase receptor type C.	0.461
ENSOMEP00000009191	LOC112137135	ENSOMEP00000009191	ENSOMEP00000015862	Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family.	Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family.	0.893
ENSOMEP00000009191	LOC112144907	ENSOMEP00000009191	ENSOMEP00000025448	Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family.	Transforming growth factor, alpha.	0.773
ENSOMEP00000009191	vegfa	ENSOMEP00000009191	ENSOMEP00000032603	Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.775
ENSOMEP00000013121	LOC112148434	ENSOMEP00000013121	ENSOMEP00000000516	Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.620
ENSOMEP00000013910	hpn	ENSOMEP00000013910	ENSOMEP00000015566	Uncharacterized protein.	Hepsin; Belongs to the peptidase S1 family.	0.467
ENSOMEP00000016487	ENSOMEP00000026367	ENSOMEP00000016487	ENSOMEP00000026367	Ig-like domain-containing protein.	Uncharacterized protein.	0.425
ENSOMEP00000016487	LOC112145370	ENSOMEP00000016487	ENSOMEP00000022924	Ig-like domain-containing protein.	Uncharacterized protein.	0.520
ENSOMEP00000016511	ENSOMEP00000026367	ENSOMEP00000016511	ENSOMEP00000026367	Ig-like domain-containing protein.	Uncharacterized protein.	0.425
ENSOMEP00000016511	LOC112145370	ENSOMEP00000016511	ENSOMEP00000022924	Ig-like domain-containing protein.	Uncharacterized protein.	0.520
ENSOMEP00000020475	LOC112145552	ENSOMEP00000020475	ENSOMEP00000023458	Signal peptide, CUB domain, EGF-like 2.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.468
ENSOMEP00000020475	LOC112149788	ENSOMEP00000020475	ENSOMEP00000006792	Signal peptide, CUB domain, EGF-like 2.	ADAM metallopeptidase domain 17a.	0.466