(29 nodes) ABC transporter type 1, transmembrane domain network (Oryzias melastigma)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC112159972	ATP-binding cassette, sub-family B (MDR/TAP), member 11b. (1364 aa)
	abcb11	ATP-binding cassette, sub-family B (MDR/TAP), member 11a. (1306 aa)
	abcd3	ATP-binding cassette, sub-family D (ALD), member 3a. (711 aa)
	LOC112153271	ATP-binding cassette, sub-family C (CFTR/MRP), member 9. (1568 aa)
	abcc8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8. (1587 aa)
	abcd4	ATP-binding cassette, sub-family D (ALD), member 4. (616 aa)
	tap1	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). (732 aa)
	LOC112160922	ATP-binding cassette, sub-family C (CFTR/MRP), member 12. (1368 aa)
	abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5. (1385 aa)
	abcd2	ATP-binding cassette, sub-family D (ALD), member 2. (734 aa)
	abcc10	ATP-binding cassette, sub-family C (CFTR/MRP), member 10. (1535 aa)
	LOC112146142	ATP-binding cassette, sub-family C (CFTR/MRP), member 1. (1529 aa)
	cftr	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1502 aa)
	ENSOMEP00000021385	ABC transmembrane type-1 domain-containing protein. (357 aa)
	LOC112158905	ATP-binding cassette, sub-family D (ALD), member 1. (749 aa)
	LOC112159448	Transporter associated with antigen processing, subunit type a. (717 aa)
	abcc3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3. (1543 aa)
	LOC112153501	Si:ch211-221f10.2. (1384 aa)
	ABCC4	ATP binding cassette subfamily C member 4. (1224 aa)
	abcb6	ATP-binding cassette, sub-family B (MDR/TAP), member 6a. (851 aa)
	LOC112143958	ATP-binding cassette, sub-family B (MDR/TAP), member 4. (1290 aa)
	abcb9	ATP-binding cassette, sub-family B (MDR/TAP), member 9. (806 aa)
	abcb7	Mitochondrial ATP-binding cassette sub-family B member 7. (746 aa)
	LOC112137504	ATP-binding cassette, sub-family C (CFTR/MRP), member 6a. (1510 aa)
	abcb10	ATP-binding cassette, sub-family B (MDR/TAP), member 10. (709 aa)
	LOC112154648	Transporter associated with antigen processing, subunit type t, teleost specific. (713 aa)
	LOC112159977	Uncharacterized protein. (1340 aa)
	LOC112161545	Uncharacterized protein. (1567 aa)
	ENSOMEP00000023062	Uncharacterized protein. (1533 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC4	LOC112143958	ENSOMEP00000005287	ENSOMEP00000024779	ATP binding cassette subfamily C member 4.	ATP-binding cassette, sub-family B (MDR/TAP), member 4.	0.473
ABCC4	LOC112159972	ENSOMEP00000005287	ENSOMEP00000022901	ATP binding cassette subfamily C member 4.	ATP-binding cassette, sub-family B (MDR/TAP), member 11b.	0.473
ABCC4	LOC112159977	ENSOMEP00000005287	ENSOMEP00000023109	ATP binding cassette subfamily C member 4.	Uncharacterized protein.	0.870
ABCC4	abcb11	ENSOMEP00000005287	ENSOMEP00000022984	ATP binding cassette subfamily C member 4.	ATP-binding cassette, sub-family B (MDR/TAP), member 11a.	0.489
ABCC4	abcb6	ENSOMEP00000005287	ENSOMEP00000006295	ATP binding cassette subfamily C member 4.	ATP-binding cassette, sub-family B (MDR/TAP), member 6a.	0.515
ABCC4	abcb7	ENSOMEP00000005287	ENSOMEP00000006389	ATP binding cassette subfamily C member 4.	Mitochondrial ATP-binding cassette sub-family B member 7.	0.517
ENSOMEP00000021385	LOC112143958	ENSOMEP00000021385	ENSOMEP00000024779	ABC transmembrane type-1 domain-containing protein.	ATP-binding cassette, sub-family B (MDR/TAP), member 4.	0.485
ENSOMEP00000021385	LOC112159972	ENSOMEP00000021385	ENSOMEP00000022901	ABC transmembrane type-1 domain-containing protein.	ATP-binding cassette, sub-family B (MDR/TAP), member 11b.	0.485
ENSOMEP00000021385	abcb11	ENSOMEP00000021385	ENSOMEP00000022984	ABC transmembrane type-1 domain-containing protein.	ATP-binding cassette, sub-family B (MDR/TAP), member 11a.	0.485
ENSOMEP00000021385	abcb6	ENSOMEP00000021385	ENSOMEP00000006295	ABC transmembrane type-1 domain-containing protein.	ATP-binding cassette, sub-family B (MDR/TAP), member 6a.	0.515
ENSOMEP00000021385	abcb7	ENSOMEP00000021385	ENSOMEP00000006389	ABC transmembrane type-1 domain-containing protein.	Mitochondrial ATP-binding cassette sub-family B member 7.	0.691
ENSOMEP00000023062	LOC112143958	ENSOMEP00000023062	ENSOMEP00000024779	Uncharacterized protein.	ATP-binding cassette, sub-family B (MDR/TAP), member 4.	0.473
ENSOMEP00000023062	LOC112159972	ENSOMEP00000023062	ENSOMEP00000022901	Uncharacterized protein.	ATP-binding cassette, sub-family B (MDR/TAP), member 11b.	0.473
ENSOMEP00000023062	abcb11	ENSOMEP00000023062	ENSOMEP00000022984	Uncharacterized protein.	ATP-binding cassette, sub-family B (MDR/TAP), member 11a.	0.473
ENSOMEP00000023062	abcb6	ENSOMEP00000023062	ENSOMEP00000006295	Uncharacterized protein.	ATP-binding cassette, sub-family B (MDR/TAP), member 6a.	0.515
ENSOMEP00000023062	abcb7	ENSOMEP00000023062	ENSOMEP00000006389	Uncharacterized protein.	Mitochondrial ATP-binding cassette sub-family B member 7.	0.517
LOC112137504	LOC112143958	ENSOMEP00000008722	ENSOMEP00000024779	ATP-binding cassette, sub-family C (CFTR/MRP), member 6a.	ATP-binding cassette, sub-family B (MDR/TAP), member 4.	0.481
LOC112137504	LOC112146142	ENSOMEP00000008722	ENSOMEP00000029491	ATP-binding cassette, sub-family C (CFTR/MRP), member 6a.	ATP-binding cassette, sub-family C (CFTR/MRP), member 1.	0.892
LOC112137504	LOC112159972	ENSOMEP00000008722	ENSOMEP00000022901	ATP-binding cassette, sub-family C (CFTR/MRP), member 6a.	ATP-binding cassette, sub-family B (MDR/TAP), member 11b.	0.481
LOC112137504	abcb11	ENSOMEP00000008722	ENSOMEP00000022984	ATP-binding cassette, sub-family C (CFTR/MRP), member 6a.	ATP-binding cassette, sub-family B (MDR/TAP), member 11a.	0.481