(12 nodes) Thiolase-like network (Oryzias melastigma)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	scp2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (540 aa)
	LOC112151519	Si:dkey-61p9.11. (2097 aa)
	acat2	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
	ENSOMEP00000012439	Coiled-coil domain containing 57. (2510 aa)
	ENSOMEP00000016606	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (543 aa)
	oxsm	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (453 aa)
	ENSOMEP00000021901	Carrier domain-containing protein. (1992 aa)
	hadhb	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (470 aa)
	LOC112151122	Carrier domain-containing protein. (2084 aa)
	acat1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (418 aa)
	ENSOMEP00000027260	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (383 aa)
	ENSOMEP00000032273	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (357 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000012439	ENSOMEP00000016606	ENSOMEP00000012439	ENSOMEP00000016606	Coiled-coil domain containing 57.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.514
ENSOMEP00000012439	ENSOMEP00000027260	ENSOMEP00000012439	ENSOMEP00000027260	Coiled-coil domain containing 57.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.537
ENSOMEP00000012439	ENSOMEP00000032273	ENSOMEP00000012439	ENSOMEP00000032273	Coiled-coil domain containing 57.	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.536
ENSOMEP00000012439	acat1	ENSOMEP00000012439	ENSOMEP00000022203	Coiled-coil domain containing 57.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.490
ENSOMEP00000012439	acat2	ENSOMEP00000012439	ENSOMEP00000005846	Coiled-coil domain containing 57.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.490
ENSOMEP00000012439	hadhb	ENSOMEP00000012439	ENSOMEP00000035933	Coiled-coil domain containing 57.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.	0.536
ENSOMEP00000012439	oxsm	ENSOMEP00000012439	ENSOMEP00000019392	Coiled-coil domain containing 57.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.937
ENSOMEP00000012439	scp2	ENSOMEP00000012439	ENSOMEP00000027268	Coiled-coil domain containing 57.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.562
ENSOMEP00000016606	ENSOMEP00000012439	ENSOMEP00000016606	ENSOMEP00000012439	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Coiled-coil domain containing 57.	0.514
ENSOMEP00000016606	ENSOMEP00000021901	ENSOMEP00000016606	ENSOMEP00000021901	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Carrier domain-containing protein.	0.514
ENSOMEP00000016606	ENSOMEP00000027260	ENSOMEP00000016606	ENSOMEP00000027260	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.989
ENSOMEP00000016606	ENSOMEP00000032273	ENSOMEP00000016606	ENSOMEP00000032273	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.996
ENSOMEP00000016606	LOC112151122	ENSOMEP00000016606	ENSOMEP00000022007	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Carrier domain-containing protein.	0.514
ENSOMEP00000016606	LOC112151519	ENSOMEP00000016606	ENSOMEP00000000266	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Si:dkey-61p9.11.	0.514
ENSOMEP00000016606	acat1	ENSOMEP00000016606	ENSOMEP00000022203	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.996
ENSOMEP00000016606	acat2	ENSOMEP00000016606	ENSOMEP00000005846	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.998
ENSOMEP00000016606	hadhb	ENSOMEP00000016606	ENSOMEP00000035933	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.	0.996
ENSOMEP00000016606	oxsm	ENSOMEP00000016606	ENSOMEP00000019392	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.932
ENSOMEP00000016606	scp2	ENSOMEP00000016606	ENSOMEP00000027268	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.924
ENSOMEP00000021901	ENSOMEP00000016606	ENSOMEP00000021901	ENSOMEP00000016606	Carrier domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.514