(53 nodes) PSI domain network (Oryzias melastigma)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSOMEP00000012136	Plexin b1a. (1941 aa)
	LOC112145639	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (789 aa)
	LOC112159532	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga; Belongs to the semaphorin family. (742 aa)
	LOC112154448	Integrin beta; Belongs to the integrin beta chain family. (825 aa)
	SEMA4G	Semaphorin 4G; Belongs to the semaphorin family. (886 aa)
	atrn	Attractin. (1364 aa)
	ENSOMEP00000004501	Uncharacterized protein; Belongs to the semaphorin family. (782 aa)
	sema3b	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family. (803 aa)
	met	MET proto-oncogene, receptor tyrosine kinase. (1398 aa)
	LOC112152372	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (796 aa)
	LOC112159662	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3H; Belongs to the semaphorin family. (762 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (904 aa)
	LOC112152343	Plexin b2b. (1848 aa)
	PLXND1	Plexin D1. (1899 aa)
	PLXNA2	Plexin A2. (1911 aa)
	ENSOMEP00000010098	Sema domain-containing protein. (647 aa)
	LOC112150975	Sema domain-containing protein. (1078 aa)
	LOC112160832	Sema domain-containing protein; Belongs to the semaphorin family. (837 aa)
	ENSOMEP00000012427	Plexin A1a. (1851 aa)
	itgb8	Integrin beta; Belongs to the integrin beta chain family. (742 aa)
	sema5b	Sema domain-containing protein. (1120 aa)
	LOC112144749	Sema domain-containing protein. (1895 aa)
	LOC112136554	Si:ch211-113g11.6; Belongs to the semaphorin family. (638 aa)
	sema4c	Uncharacterized protein; Belongs to the semaphorin family. (864 aa)
	LOC112147599	Semaphorin 4e; Belongs to the semaphorin family. (768 aa)
	LOC112159039	Plexin A2. (1977 aa)
	itgb5	Integrin beta; Belongs to the integrin beta chain family. (800 aa)
	LOC112152745	Semaphorin 7A; Belongs to the semaphorin family. (648 aa)
	LOC112146702	Integrin beta; Belongs to the integrin beta chain family. (783 aa)
	LOC112145377	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (796 aa)
	ENSOMEP00000021604	Macrophage stimulating 1 receptor b. (1374 aa)
	LOC112145119	Plexin b1b. (2118 aa)
	LOC112145561	Macrophage stimulating 1 receptor a. (1366 aa)
	LOC112150085	Si:ch211-129c21.1; Belongs to the semaphorin family. (808 aa)
	LOC112145792	Si:dkey-49n23.1; Belongs to the semaphorin family. (804 aa)
	sema3c	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (764 aa)
	LOC112154644	Uncharacterized protein; Belongs to the semaphorin family. (887 aa)
	LOC112154247	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (845 aa)
	LOC112136788	Sema domain-containing protein. (1085 aa)
	sema3g	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family. (775 aa)
	sema3d	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (795 aa)
	sema3e	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; Belongs to the semaphorin family. (783 aa)
	plxna4	Plexin A4. (1916 aa)
	LOC112162085	Sema domain-containing protein; Belongs to the semaphorin family. (817 aa)
	ENSOMEP00000028435	Si:ch211-106h4.6. (545 aa)
	ENSOMEP00000030424	Integrin beta; Belongs to the integrin beta chain family. (754 aa)
	ENSOMEP00000031492	Multiple EGF-like-domains 8. (2827 aa)
	ENSOMEP00000032111	Attractin-like 1a. (1334 aa)
	ENSOMEP00000032223	Integrin beta. (786 aa)
	LOC112161149	Uncharacterized protein; Belongs to the semaphorin family. (622 aa)
	atrnl1	Attractin-like 1b. (1372 aa)
	LOC112152913	Sema domain-containing protein; Belongs to the semaphorin family. (834 aa)
	ENSOMEP00000036101	Sema domain-containing protein. (493 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000004501	ENSOMEP00000010098	ENSOMEP00000004501	ENSOMEP00000010098	Uncharacterized protein; Belongs to the semaphorin family.	Sema domain-containing protein.	0.629
ENSOMEP00000004501	ENSOMEP00000012136	ENSOMEP00000004501	ENSOMEP00000012136	Uncharacterized protein; Belongs to the semaphorin family.	Plexin b1a.	0.629
ENSOMEP00000004501	ENSOMEP00000012427	ENSOMEP00000004501	ENSOMEP00000012427	Uncharacterized protein; Belongs to the semaphorin family.	Plexin A1a.	0.616
ENSOMEP00000004501	ENSOMEP00000021604	ENSOMEP00000004501	ENSOMEP00000021604	Uncharacterized protein; Belongs to the semaphorin family.	Macrophage stimulating 1 receptor b.	0.756
ENSOMEP00000004501	ENSOMEP00000036101	ENSOMEP00000004501	ENSOMEP00000036101	Uncharacterized protein; Belongs to the semaphorin family.	Sema domain-containing protein.	0.490
ENSOMEP00000004501	LOC112144749	ENSOMEP00000004501	ENSOMEP00000015177	Uncharacterized protein; Belongs to the semaphorin family.	Sema domain-containing protein.	0.616
ENSOMEP00000004501	LOC112145119	ENSOMEP00000004501	ENSOMEP00000022199	Uncharacterized protein; Belongs to the semaphorin family.	Plexin b1b.	0.629
ENSOMEP00000004501	LOC112145561	ENSOMEP00000004501	ENSOMEP00000022523	Uncharacterized protein; Belongs to the semaphorin family.	Macrophage stimulating 1 receptor a.	0.756
ENSOMEP00000004501	LOC112147599	ENSOMEP00000004501	ENSOMEP00000018277	Uncharacterized protein; Belongs to the semaphorin family.	Semaphorin 4e; Belongs to the semaphorin family.	0.552
ENSOMEP00000004501	LOC112152343	ENSOMEP00000004501	ENSOMEP00000007743	Uncharacterized protein; Belongs to the semaphorin family.	Plexin b2b.	0.629
ENSOMEP00000004501	LOC112159039	ENSOMEP00000004501	ENSOMEP00000018829	Uncharacterized protein; Belongs to the semaphorin family.	Plexin A2.	0.616
ENSOMEP00000004501	PLXNA2	ENSOMEP00000004501	ENSOMEP00000009738	Uncharacterized protein; Belongs to the semaphorin family.	Plexin A2.	0.616
ENSOMEP00000004501	PLXND1	ENSOMEP00000004501	ENSOMEP00000007948	Uncharacterized protein; Belongs to the semaphorin family.	Plexin D1.	0.616
ENSOMEP00000004501	met	ENSOMEP00000004501	ENSOMEP00000006177	Uncharacterized protein; Belongs to the semaphorin family.	MET proto-oncogene, receptor tyrosine kinase.	0.756
ENSOMEP00000004501	plxna4	ENSOMEP00000004501	ENSOMEP00000026517	Uncharacterized protein; Belongs to the semaphorin family.	Plexin A4.	0.616
ENSOMEP00000010098	ENSOMEP00000004501	ENSOMEP00000010098	ENSOMEP00000004501	Sema domain-containing protein.	Uncharacterized protein; Belongs to the semaphorin family.	0.629
ENSOMEP00000010098	ENSOMEP00000021604	ENSOMEP00000010098	ENSOMEP00000021604	Sema domain-containing protein.	Macrophage stimulating 1 receptor b.	0.655
ENSOMEP00000010098	LOC112136554	ENSOMEP00000010098	ENSOMEP00000016185	Sema domain-containing protein.	Si:ch211-113g11.6; Belongs to the semaphorin family.	0.628
ENSOMEP00000010098	LOC112136788	ENSOMEP00000010098	ENSOMEP00000025639	Sema domain-containing protein.	Sema domain-containing protein.	0.724
ENSOMEP00000010098	LOC112145377	ENSOMEP00000010098	ENSOMEP00000021547	Sema domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family.	0.513