51 items (Oryzias melastigma) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC112162798	Betacellulin, epidermal growth factor family member. (185 aa)
	ENSOMEP00000029504	Receptor protein-tyrosine kinase. (1346 aa)
	LOC112162336	Signal transducer and activator of transcription. (786 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	ENSOMEP00000027472	Estrogen receptor 1. (522 aa)
	erbb3	Protein kinase domain-containing protein. (1411 aa)
	wwox	WW domain containing oxidoreductase. (412 aa)
	ENSOMEP00000026842	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (410 aa)
	ADAP1	ArfGAP with dual PH domains 1. (366 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)
	ENSOMEP00000025528	MAX dimerization protein 4. (214 aa)
	LOC112147412	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	yap1	Yes-associated protein 1. (458 aa)
	ENSOMEP00000022058	Receptor protein-tyrosine kinase. (1207 aa)
	LOC112146942	Signal transducer and activator of transcription. (786 aa)
	NCSTN	Nicastrin. (697 aa)
	ENSOMEP00000021152	EGF-like domain-containing protein. (117 aa)
	ENSOMEP00000020966	Ribosomal protein S27a. (183 aa)
	LOC112138811	Neuregulin 2a. (709 aa)
	aph1a	APH1B gamma secretase subunit. (258 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	psenen	Presenilin enhancer, gamma-secretase subunit. (101 aa)
	ENSOMEP00000016094	EGF-like domain-containing protein. (474 aa)
	LOC112156941	Uncharacterized protein. (380 aa)
	LOC112159600	Erb-b2 receptor tyrosine kinase 3b. (1431 aa)
	LOC112158705	Tyrosine-protein kinase. (551 aa)
	LOC112144968	E3 ubiquitin-protein ligase. (862 aa)
	LOC112153097	Neuregulin 2b. (711 aa)
	LOC112140352	EGF-like domain-containing protein. (596 aa)
	LOC112148513	EGF-like domain-containing protein. (154 aa)
	LOC112145886	ArfGAP with dual PH domains 2. (378 aa)
	ENSOMEP00000012874	E3 ubiquitin-protein ligase. (776 aa)
	src	Tyrosine-protein kinase. (550 aa)
	KRAS	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	SHC4	SHC adaptor protein 4. (494 aa)
	LOC112146549	Uncharacterized protein. (377 aa)
	ENSOMEP00000006934	Epidermal growth factor. (921 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (588 aa)
	ENSOMEP00000002833	Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
	ENSOMEP00000001362	E3 ubiquitin-protein ligase. (903 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1238 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (869 aa)
	LOC112137157	Uncharacterized protein. (377 aa)
	ENSOMEP00000031576	Fibronectin type III domain containing 3Ba. (1233 aa)
	LOC112146394	Zgc:55558. (186 aa)
	LOC112149585	Crystallin, beta B1, like 3; Belongs to the beta/gamma-crystallin family. (209 aa)
	wwp1	WW domain containing E3 ubiquitin protein ligase 1. (963 aa)
	stmn1	Stathmin; Belongs to the stathmin family. (152 aa)
	LOC112148748	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (473 aa)
	ENSOMEP00000035400	Ubiquitin-like domain-containing protein. (137 aa)
	LOC112154686	Neuregulin 3b. (752 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	ENSOMEP00000002833	ENSOMEP00000031024	ENSOMEP00000002833	Cold shock domain containing E1, RNA-binding.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.687
CSDE1	ENSOMEP00000006934	ENSOMEP00000031024	ENSOMEP00000006934	Cold shock domain containing E1, RNA-binding.	Epidermal growth factor.	0.627
CSDE1	ENSOMEP00000020966	ENSOMEP00000031024	ENSOMEP00000020966	Cold shock domain containing E1, RNA-binding.	Ribosomal protein S27a.	0.679
CSDE1	ENSOMEP00000022058	ENSOMEP00000031024	ENSOMEP00000022058	Cold shock domain containing E1, RNA-binding.	Receptor protein-tyrosine kinase.	0.687
CSDE1	ENSOMEP00000029504	ENSOMEP00000031024	ENSOMEP00000029504	Cold shock domain containing E1, RNA-binding.	Receptor protein-tyrosine kinase.	0.687
CSDE1	ENSOMEP00000035400	ENSOMEP00000031024	ENSOMEP00000035400	Cold shock domain containing E1, RNA-binding.	Ubiquitin-like domain-containing protein.	0.686
CSDE1	LOC112138811	ENSOMEP00000031024	ENSOMEP00000018482	Cold shock domain containing E1, RNA-binding.	Neuregulin 2a.	0.534
CSDE1	LOC112140352	ENSOMEP00000031024	ENSOMEP00000014294	Cold shock domain containing E1, RNA-binding.	EGF-like domain-containing protein.	0.534
CSDE1	LOC112147412	ENSOMEP00000031024	ENSOMEP00000025220	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.733
CSDE1	LOC112148513	ENSOMEP00000031024	ENSOMEP00000014202	Cold shock domain containing E1, RNA-binding.	EGF-like domain-containing protein.	0.580
CSDE1	LOC112153097	ENSOMEP00000031024	ENSOMEP00000014670	Cold shock domain containing E1, RNA-binding.	Neuregulin 2b.	0.534
CSDE1	LOC112158705	ENSOMEP00000031024	ENSOMEP00000015391	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.634
CSDE1	LOC112159600	ENSOMEP00000031024	ENSOMEP00000015474	Cold shock domain containing E1, RNA-binding.	Erb-b2 receptor tyrosine kinase 3b.	0.687
CSDE1	LOC112162798	ENSOMEP00000031024	ENSOMEP00000004398	Cold shock domain containing E1, RNA-binding.	Betacellulin, epidermal growth factor family member.	0.591
CSDE1	PIK3CA	ENSOMEP00000031024	ENSOMEP00000028331	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.733
CSDE1	SHC4	ENSOMEP00000031024	ENSOMEP00000008409	Cold shock domain containing E1, RNA-binding.	SHC adaptor protein 4.	0.511
CSDE1	erbb3	ENSOMEP00000031024	ENSOMEP00000027271	Cold shock domain containing E1, RNA-binding.	Protein kinase domain-containing protein.	0.687
CSDE1	grb2	ENSOMEP00000031024	ENSOMEP00000026652	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2b.	0.808
CSDE1	shc1	ENSOMEP00000031024	ENSOMEP00000006033	Cold shock domain containing E1, RNA-binding.	SHC (Src homology 2 domain containing) transforming protein 1.	0.511
CSDE1	src	ENSOMEP00000031024	ENSOMEP00000012169	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.634