STRINGSTRING
LOC112145521 LOC112145521 ENSOMEP00000015093 ENSOMEP00000015093 LOC112152993 LOC112152993 TGFB3 TGFB3 LOC112146278 LOC112146278 LOC112149681 LOC112149681 SMAD3-2 SMAD3-2 PARD3 PARD3 fkbp1b fkbp1b e2f4 e2f4 mkx mkx smad2 smad2 tgfb3 tgfb3 ENSOMEP00000019026 ENSOMEP00000019026 bambi bambi itgb5 itgb5 zfyve9 zfyve9 LOC112145252 LOC112145252 LOC112146702 LOC112146702 LOC112149754 LOC112149754 ENSOMEP00000020966 ENSOMEP00000020966 ENSOMEP00000021375 ENSOMEP00000021375 LOC112148176 LOC112148176 LOC112145260 LOC112145260 LTBP3 LTBP3 ENSOMEP00000023058 ENSOMEP00000023058 LOC112136593 LOC112136593 LOC112151615 LOC112151615 smurf1 smurf1 men1 men1 ENSOMEP00000014669 ENSOMEP00000014669 LOC112147514 LOC112147514 TGFBR2 TGFBR2 LOC112159397 LOC112159397 SMURF2 SMURF2 ENSOMEP00000029602 ENSOMEP00000029602 irx1 irx1 kxd1 kxd1 ENSOMEP00000027927 ENSOMEP00000027927 ENSOMEP00000028050 ENSOMEP00000028050 cdk19 cdk19 furin furin ENSOMEP00000029184 ENSOMEP00000029184 ENSOMEP00000029314 ENSOMEP00000029314 ENSOMEP00000029448 ENSOMEP00000029448 mapk1 mapk1 SMAD3 SMAD3 ENSOMEP00000007753 ENSOMEP00000007753 LOC112146480 LOC112146480 smad7 smad7 ENSOMEP00000006747 ENSOMEP00000006747 ENSOMEP00000006733 ENSOMEP00000006733 LOC112160024 LOC112160024 cdk8 cdk8 nedd4l nedd4l ENSOMEP00000005837 ENSOMEP00000005837 ldlrad4 ldlrad4 LOC112155588 LOC112155588 ENSOMEP00000003820 ENSOMEP00000003820 LOC112154448 LOC112154448 ENSOMEP00000003060 ENSOMEP00000003060 ENSOMEP00000002833 ENSOMEP00000002833 LOC112159231 LOC112159231 pard3 pard3 LOC112161061 LOC112161061 ENSOMEP00000001682 ENSOMEP00000001682 LOC112142874 LOC112142874 ENSOMEP00000001119 ENSOMEP00000001119 meis2 meis2 strap strap ENSOMEP00000030424 ENSOMEP00000030424 ENSOMEP00000030515 ENSOMEP00000030515 atp1b4 atp1b4 LOC112155766 LOC112155766 cbl cbl irx3 irx3 ENSOMEP00000031494 ENSOMEP00000031494 LOC112143591 LOC112143591 LOC112145685 LOC112145685 ENSOMEP00000032207 ENSOMEP00000032207 LOC112159500 LOC112159500 LOC112149944 LOC112149944 ENSOMEP00000032745 ENSOMEP00000032745 ccnc ccnc ENSOMEP00000033103 ENSOMEP00000033103 ltbp1 ltbp1 ltbp2 ltbp2 LOC112152883 LOC112152883 snw1 snw1 LOC112148478 LOC112148478 ENSOMEP00000034858 ENSOMEP00000034858 ENSOMEP00000035400 ENSOMEP00000035400 ENSOMEP00000014289 ENSOMEP00000014289 irx6 irx6 itgb8 itgb8 ENSOMEP00000013532 ENSOMEP00000013532 ENSOMEP00000013440 ENSOMEP00000013440 ENSOMEP00000013193 ENSOMEP00000013193 LOC112143132 LOC112143132 irx2 irx2 LOC112143180 LOC112143180 ENSOMEP00000012190 ENSOMEP00000012190 ENSOMEP00000011622 ENSOMEP00000011622 ENSOMEP00000011614 ENSOMEP00000011614 ENSOMEP00000011604 ENSOMEP00000011604 ENSOMEP00000011579 ENSOMEP00000011579 arhgef18 arhgef18 skil skil LOC112157656 LOC112157656 ccnt2 ccnt2 LOC112147850 LOC112147850 ENSOMEP00000010197 ENSOMEP00000010197 ENSOMEP00000010096 ENSOMEP00000010096 junb junb LOC112139043 LOC112139043 FBN1 FBN1 tfdp1 tfdp1 ENSOMEP00000009385 ENSOMEP00000009385 stub1 stub1 trim33 trim33
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC112145521JunB proto-oncogene, AP-1 transcription factor subunit a. (331 aa)
ENSOMEP00000015093Par-3 family cell polarity regulator beta b. (1165 aa)
LOC112152993Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
LOC112146278Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (389 aa)
LOC112149681Uncharacterized protein. (1677 aa)
SMAD3-2Mothers against decapentaplegic homolog. (429 aa)
PARD3Par-3 family cell polarity regulator. (1371 aa)
fkbp1bPeptidylprolyl isomerase. (113 aa)
e2f4E2F transcription factor 4. (386 aa)
mkxMohawk homeobox a. (358 aa)
smad2Mothers against decapentaplegic homolog. (473 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (406 aa)
ENSOMEP00000019026Cyclin K; Belongs to the cyclin family. (454 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
itgb5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
zfyve9Zinc finger, FYVE domain containing 9a. (1164 aa)
LOC112145252V-ski avian sarcoma viral oncogene homolog b. (683 aa)
LOC112146702Integrin beta; Belongs to the integrin beta chain family. (783 aa)
LOC112149754Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
ENSOMEP00000020966Ribosomal protein S27a. (183 aa)
ENSOMEP00000021375Uncharacterized protein. (79 aa)
LOC112148176Mothers against decapentaplegic homolog. (510 aa)
LOC112145260Uncharacterized protein. (324 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1242 aa)
ENSOMEP00000023058Mothers against decapentaplegic homolog. (493 aa)
LOC112136593Mothers against decapentaplegic homolog. (536 aa)
LOC112151615TGFB-induced factor homeobox 1. (301 aa)
smurf1E3 ubiquitin-protein ligase. (731 aa)
men1Multiple endocrine neoplasia I. (625 aa)
ENSOMEP00000014669Nuclear receptor corepressor 2. (2130 aa)
LOC112147514Mohawk homeobox b. (387 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LOC112159397Peptidylprolyl isomerase. (108 aa)
SMURF2E3 ubiquitin-protein ligase. (775 aa)
ENSOMEP00000029602Iroquois homeobox 4b. (365 aa)
irx1Iroquois homeobox 1b. (431 aa)
kxd1KxDL motif containing 1. (195 aa)
ENSOMEP00000027927Ubiquitin-like domain-containing protein. (77 aa)
ENSOMEP00000028050Cyclin Q. (160 aa)
cdk19Cyclin-dependent kinase 19; Belongs to the protein kinase superfamily. (487 aa)
furinFurin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (835 aa)
ENSOMEP00000029184V-ski avian sarcoma viral oncogene homolog a. (486 aa)
ENSOMEP00000029314Uncharacterized protein. (271 aa)
ENSOMEP00000029448NEDD8 ubiquitin like modifier. (94 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ENSOMEP00000007753Uncharacterized protein. (57 aa)
LOC112146480E3 ubiquitin-protein ligase. (770 aa)
smad7Mothers against decapentaplegic homolog. (375 aa)
ENSOMEP00000006747Poly [ADP-ribose] polymerase. (395 aa)
ENSOMEP00000006733PARP-type domain-containing protein. (104 aa)
LOC112160024Uncharacterized protein. (1188 aa)
cdk8Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (463 aa)
nedd4lNEDD4 like E3 ubiquitin protein ligase. (1220 aa)
ENSOMEP00000005837Uncharacterized protein. (261 aa)
ldlrad4Low density lipoprotein receptor class A domain containing 4b. (296 aa)
LOC112155588TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (574 aa)
ENSOMEP00000003820Cyclin-dependent kinase 9 (CDC2-related kinase). (343 aa)
LOC112154448Integrin beta; Belongs to the integrin beta chain family. (825 aa)
ENSOMEP00000003060Cyclin T2b; Belongs to the cyclin family. (551 aa)
ENSOMEP00000002833Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
LOC112159231Peptidylprolyl isomerase. (109 aa)
pard3Par-3 family cell polarity regulator alpha, b. (1420 aa)
LOC112161061Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (810 aa)
ENSOMEP00000001682F11 receptor, tandem duplicate 1. (282 aa)
LOC112142874Uncharacterized protein. (856 aa)
ENSOMEP00000001119Ring finger protein 111. (981 aa)
meis2Meis homeobox 2a. (471 aa)
strapSerine/threonine kinase receptor associated protein. (329 aa)
ENSOMEP00000030424Integrin beta; Belongs to the integrin beta chain family. (754 aa)
ENSOMEP00000030515Uncharacterized protein. (309 aa)
atp1b4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (342 aa)
LOC112155766NEDD8 ubiquitin like modifier. (80 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (942 aa)
irx3Iroquois homeobox 3a. (421 aa)
ENSOMEP00000031494Homeobox domain-containing protein. (307 aa)
LOC112143591Cbl proto-oncogene C, E3 ubiquitin protein ligase. (560 aa)
LOC112145685Homeobox domain-containing protein. (496 aa)
ENSOMEP00000032207Retinoblastoma-like 1 (p107). (1040 aa)
LOC112159500Homeobox domain-containing protein. (302 aa)
LOC112149944Myeloid ecotropic viral integration site 3. (420 aa)
ENSOMEP00000032745MH1 domain-containing protein. (63 aa)
ccncCyclin C; Belongs to the cyclin family. (287 aa)
ENSOMEP00000033103Uncharacterized protein. (597 aa)
ltbp1Latent transforming growth factor beta binding protein 1. (1398 aa)
ltbp2Uncharacterized protein. (1979 aa)
LOC112152883Par-6 family cell polarity regulator alpha. (389 aa)
snw1SNW domain containing 1. (564 aa)
LOC112148478Mothers against decapentaplegic homolog. (467 aa)
ENSOMEP00000034858Integrin beta; Belongs to the integrin beta chain family. (395 aa)
ENSOMEP00000035400Ubiquitin-like domain-containing protein. (137 aa)
ENSOMEP00000014289Iroquois homeobox 5a. (453 aa)
irx6Iroquois homeobox 6a. (467 aa)
itgb8Integrin beta; Belongs to the integrin beta chain family. (742 aa)
ENSOMEP00000013532Uncharacterized protein. (98 aa)
ENSOMEP00000013440Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2326 aa)
ENSOMEP00000013193Cyclin T1; Belongs to the cyclin family. (681 aa)
LOC112143132Iroquois homeobox 1a. (498 aa)
irx2Iroquois homeobox 2a. (504 aa)
LOC112143180Iroquois homeobox 4a. (468 aa)
ENSOMEP00000012190Uncharacterized protein. (157 aa)
ENSOMEP00000011622Uncharacterized protein. (595 aa)
ENSOMEP00000011614EGF-like domain-containing protein. (46 aa)
ENSOMEP00000011604EGF-like domain-containing protein. (85 aa)
ENSOMEP00000011579Uncharacterized protein. (247 aa)
arhgef18Rho/rac guanine nucleotide exchange factor (GEF) 18b. (1603 aa)
skilSKI-like proto-oncogene a. (751 aa)
LOC112157656Meis homeobox 2b. (397 aa)
ccnt2Cyclin T2; Belongs to the cyclin family. (685 aa)
LOC112147850E2F transcription factor 5. (362 aa)
ENSOMEP00000010197Protein kinase C, zeta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (637 aa)
ENSOMEP00000010096c-SKI_SMAD_bind domain-containing protein. (260 aa)
junbJunB proto-oncogene, AP-1 transcription factor subunit b. (327 aa)
LOC112139043Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
FBN1Fibrillin 1. (2877 aa)
tfdp1Transcription factor. (413 aa)
ENSOMEP00000009385Nuclear receptor corepressor 1. (2228 aa)
stub1STIP1 homology and U-Box containing protein 1. (284 aa)
trim33Tripartite motif containing 33. (1177 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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