70 items (Oryzias melastigma) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC112144774	Cell division cycle 42. (191 aa)
	LOC112139281	Uncharacterized protein. (176 aa)
	ENSOMEP00000035853	SH3 domain-containing protein. (115 aa)
	LOC112160674	SH3-domain GRB2-like 3a. (383 aa)
	ENSOMEP00000035400	Ubiquitin-like domain-containing protein. (137 aa)
	ptprk	Protein tyrosine phosphatase receptor type K. (1473 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	LOC112149585	Crystallin, beta B1, like 3; Belongs to the beta/gamma-crystallin family. (209 aa)
	LOC112143591	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (560 aa)
	LOC112146394	Zgc:55558. (186 aa)
	ENSOMEP00000031576	Fibronectin type III domain containing 3Ba. (1233 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (942 aa)
	LOC112148660	EGF-like domain-containing protein. (162 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (869 aa)
	LOC112152938	Tyrosine-protein kinase. (447 aa)
	cd2ap	CD2-associated protein. (656 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
	arhgef7	Rho guanine nucleotide exchange factor (GEF) 7a. (800 aa)
	ENSOMEP00000028606	SH3 domain-containing protein. (102 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	lrig2	Leucine-rich repeats and immunoglobulin-like domains 2. (1064 aa)
	lrig1	Leucine-rich repeats and immunoglobulin-like domains 1. (1034 aa)
	aamp	Angio-associated, migratory cell protein. (416 aa)
	LOC112139945	BAR domain-containing protein. (364 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)
	ENSOMEP00000026323	Epidermal growth factor receptor pathway substrate 15-like 1a. (955 aa)
	hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (768 aa)
	LOC112144907	Transforming growth factor, alpha. (237 aa)
	LOC112147412	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	ENSOMEP00000024842	SH3-domain GRB2-like 1b. (457 aa)
	spry2	Sprouty RTK signaling antagonist 2. (417 aa)
	ptpn3	Protein tyrosine phosphatase non-receptor type 3. (871 aa)
	ENSOMEP00000022558	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (524 aa)
	ENSOMEP00000000147	SH3-domain kinase binding protein 1. (534 aa)
	LOC112155731	PH domain-containing protein. (737 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1238 aa)
	LOC112142874	Uncharacterized protein. (856 aa)
	ENSOMEP00000002833	Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
	gab1	GRB2-associated binding protein 1. (762 aa)
	CDC42	Cell division cycle 42. (191 aa)
	ENSOMEP00000004242	Uncharacterized protein. (233 aa)
	LOC112157004	SH3 domain containing GRB2 like 2a, endophilin A1. (363 aa)
	LOC112162798	Betacellulin, epidermal growth factor family member. (185 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (588 aa)
	rnf222	RING-type domain-containing protein. (212 aa)
	LOC112150209	Leupaxin. (389 aa)
	ENSOMEP00000006934	Epidermal growth factor. (921 aa)
	LOC112138373	Rho guanine nucleotide exchange factor (GEF) 7b. (843 aa)
	SHC4	SHC adaptor protein 4. (494 aa)
	eps15	Epidermal growth factor receptor pathway substrate 15. (1105 aa)
	KRAS	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	stam	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1. (515 aa)
	LOC112147568	Uncharacterized protein. (860 aa)
	pag1	Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (440 aa)
	LOC112143725	Uncharacterized protein. (191 aa)
	src	Tyrosine-protein kinase. (550 aa)
	PTPRM	Protein tyrosine phosphatase receptor type M. (892 aa)
	LOC112148513	EGF-like domain-containing protein. (154 aa)
	LOC112137131	Uncharacterized protein. (191 aa)
	LOC112158705	Tyrosine-protein kinase. (551 aa)
	stam2	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2. (505 aa)
	LOC112148168	Uncharacterized protein. (621 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	ENSOMEP00000017345	SH3 domain containing 21. (455 aa)
	LOC112147606	SH3-domain GRB2-like 1a. (366 aa)
	ENSOMEP00000019328	Uncharacterized protein. (233 aa)
	TGFB1I1	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (479 aa)
	ENSOMEP00000020966	Ribosomal protein S27a. (183 aa)
	lrig3	Leucine-rich repeats and immunoglobulin-like domains 3. (1095 aa)
	ptprt	Protein tyrosine phosphatase receptor type T. (1509 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	CSDE1	ENSOMEP00000003168	ENSOMEP00000031024	Cell division cycle 42.	Cold shock domain containing E1, RNA-binding.	0.610
CDC42	CSK	ENSOMEP00000003168	ENSOMEP00000032085	Cell division cycle 42.	Tyrosine-protein kinase.	0.487
CDC42	ENSOMEP00000000147	ENSOMEP00000003168	ENSOMEP00000000147	Cell division cycle 42.	SH3-domain kinase binding protein 1.	0.630
CDC42	ENSOMEP00000002833	ENSOMEP00000003168	ENSOMEP00000002833	Cell division cycle 42.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.706
CDC42	ENSOMEP00000006934	ENSOMEP00000003168	ENSOMEP00000006934	Cell division cycle 42.	Epidermal growth factor.	0.726
CDC42	ENSOMEP00000017345	ENSOMEP00000003168	ENSOMEP00000017345	Cell division cycle 42.	SH3 domain containing 21.	0.630
CDC42	ENSOMEP00000020966	ENSOMEP00000003168	ENSOMEP00000020966	Cell division cycle 42.	Ribosomal protein S27a.	0.715
CDC42	ENSOMEP00000022558	ENSOMEP00000003168	ENSOMEP00000022558	Cell division cycle 42.	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.	0.599
CDC42	ENSOMEP00000028606	ENSOMEP00000003168	ENSOMEP00000028606	Cell division cycle 42.	SH3 domain-containing protein.	0.569
CDC42	ENSOMEP00000035400	ENSOMEP00000003168	ENSOMEP00000035400	Cell division cycle 42.	Ubiquitin-like domain-containing protein.	0.732
CDC42	ENSOMEP00000035853	ENSOMEP00000003168	ENSOMEP00000035853	Cell division cycle 42.	SH3 domain-containing protein.	0.549
CDC42	KRAS	ENSOMEP00000003168	ENSOMEP00000010002	Cell division cycle 42.	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	0.610
CDC42	LOC112137131	ENSOMEP00000003168	ENSOMEP00000014906	Cell division cycle 42.	Uncharacterized protein.	0.628
CDC42	LOC112138373	ENSOMEP00000003168	ENSOMEP00000008408	Cell division cycle 42.	Rho guanine nucleotide exchange factor (GEF) 7b.	0.821
CDC42	LOC112139281	ENSOMEP00000003168	ENSOMEP00000036040	Cell division cycle 42.	Uncharacterized protein.	0.628
CDC42	LOC112142874	ENSOMEP00000003168	ENSOMEP00000001613	Cell division cycle 42.	Uncharacterized protein.	0.676
CDC42	LOC112143591	ENSOMEP00000003168	ENSOMEP00000031882	Cell division cycle 42.	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	0.676
CDC42	LOC112143725	ENSOMEP00000003168	ENSOMEP00000012109	Cell division cycle 42.	Uncharacterized protein.	0.860
CDC42	LOC112144907	ENSOMEP00000003168	ENSOMEP00000025448	Cell division cycle 42.	Transforming growth factor, alpha.	0.634
CDC42	LOC112146394	ENSOMEP00000003168	ENSOMEP00000031698	Cell division cycle 42.	Zgc:55558.	0.610