76 items (Oryzias melastigma) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	psme2	Proteasome activator subunit 2. (243 aa)
	ENSOMEP00000002833	Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
	ENSOMEP00000035400	Ubiquitin-like domain-containing protein. (137 aa)
	cdk2	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
	ENSOMEP00000034008	Proteasome subunit beta 9a. (114 aa)
	LOC112140154	Proteasome subunit beta 12. (217 aa)
	psma3	Proteasome subunit alpha type. (255 aa)
	psmd2	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)
	skp1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	psma1	Proteasome subunit alpha type. (267 aa)
	ccna2	Cyclin A2; Belongs to the cyclin family. (431 aa)
	psmd9	Proteasome 26S subunit, non-ATPase 9. (212 aa)
	psmd8	Proteasome 26S subunit, non-ATPase 8. (265 aa)
	psmd11	Proteasome 26S subunit, non-ATPase 11b. (422 aa)
	psmb3	Proteasome subunit beta. (206 aa)
	skp2	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (428 aa)
	LOC112150025	Proteasome subunit alpha type. (246 aa)
	LOC112137399	Proteasome subunit beta. (272 aa)
	LOC112137393	Proteasome subunit beta. (275 aa)
	LOC112137408	Proteasome subunit beta 12. (217 aa)
	psme1	Proteasome activator subunit 1. (261 aa)
	ENSOMEP00000030940	Tyrosine-protein kinase. (496 aa)
	LOC112144588	Cyclin-dependent kinase inhibitor 1A. (164 aa)
	psmd10	Proteasome 26S subunit, non-ATPase 10. (226 aa)
	psmc2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
	ENSOMEP00000028219	Proteasome endopeptidase complex. (228 aa)
	ENSOMEP00000027927	Ubiquitin-like domain-containing protein. (77 aa)
	ENSOMEP00000027783	Proteasome subunit beta; Belongs to the peptidase T1B family. (225 aa)
	kxd1	KxDL motif containing 1. (195 aa)
	psmd7	Proteasome 26S subunit, non-ATPase 7. (324 aa)
	ENSOMEP00000026888	Proteasome 26S subunit, non-ATPase 5. (475 aa)
	psmd12	Proteasome 26S subunit, non-ATPase 12. (456 aa)
	LOC112150937	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (108 aa)
	ENSOMEP00000026336	PROTEASOME_ALPHA_1 domain-containing protein. (50 aa)
	psma4	Proteasome subunit alpha type. (261 aa)
	ENSOMEP00000025203	Proteasome 26S subunit, non-ATPase 4b. (367 aa)
	psmb2	Proteasome subunit beta. (199 aa)
	cul1	Cullin 1b; Belongs to the cullin family. (777 aa)
	psmc4	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
	ENSOMEP00000024089	Uncharacterized protein. (154 aa)
	ENSOMEP00000020966	Ribosomal protein S27a. (183 aa)
	psmc5	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
	cdk4	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (320 aa)
	psmd1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
	ccne2	Cyclin E2; Belongs to the cyclin family. (395 aa)
	ccne1	Cyclin E1; Belongs to the cyclin family. (423 aa)
	ENSOMEP00000019316	Proteasome 26S subunit, non-ATPase 3. (567 aa)
	LOC112140152	Proteasome subunit beta. (275 aa)
	LOC112140153	Proteasome subunit beta. (275 aa)
	psmb7	Proteasome subunit beta. (307 aa)
	ENSOMEP00000015819	Protein kinase domain-containing protein. (358 aa)
	psma2	Proteasome subunit alpha type. (234 aa)
	LOC112136178	Proteasome subunit beta. (216 aa)
	psmd14	Proteasome 26S subunit, non-ATPase 14. (310 aa)
	ENSOMEP00000012955	Uncharacterized protein. (171 aa)
	LOC112158072	Cyclin-dependent kinase inhibitor 1D. (177 aa)
	ENSOMEP00000012830	Proteasome subunit alpha type. (292 aa)
	psmc1	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
	LOC112147624	Proteasome subunit beta. (271 aa)
	psmf1	Proteasome inhibitor subunit 1. (313 aa)
	ENSOMEP00000011443	Cyclin D1; Belongs to the cyclin family. (290 aa)
	ccna1	Cyclin A1; Belongs to the cyclin family. (457 aa)
	psmc6	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
	psmd13	Proteasome 26S subunit, non-ATPase 13. (378 aa)
	psmd6	Proteasome 26S subunit, non-ATPase 6. (389 aa)
	ENSOMEP00000007070	VWFA domain-containing protein. (229 aa)
	cdkn1b	Cyclin-dependent kinase inhibitor 1Bb. (180 aa)
	psmb6	Proteasome subunit beta. (232 aa)
	LOC112162651	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (129 aa)
	PSMD4	Proteasome 26S subunit, non-ATPase 4a. (372 aa)
	cdkn1c	Uncharacterized protein. (207 aa)
	psmb1	Proteasome subunit beta. (237 aa)
	psmc3	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
	psma5	Proteasome subunit alpha type. (241 aa)
	LOC112144185	Proteasome subunit beta. (278 aa)
	psme3	Proteasome activator subunit 3. (256 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000002833	ENSOMEP00000007070	ENSOMEP00000002833	ENSOMEP00000007070	Ubiquitin A-52 residue ribosomal protein fusion product 1.	VWFA domain-containing protein.	0.959
ENSOMEP00000002833	ENSOMEP00000012830	ENSOMEP00000002833	ENSOMEP00000012830	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Proteasome subunit alpha type.	0.951
ENSOMEP00000002833	ENSOMEP00000012955	ENSOMEP00000002833	ENSOMEP00000012955	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Uncharacterized protein.	0.813
ENSOMEP00000002833	ENSOMEP00000015819	ENSOMEP00000002833	ENSOMEP00000015819	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Protein kinase domain-containing protein.	0.772
ENSOMEP00000002833	ENSOMEP00000019316	ENSOMEP00000002833	ENSOMEP00000019316	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Proteasome 26S subunit, non-ATPase 3.	0.970
ENSOMEP00000002833	ENSOMEP00000020966	ENSOMEP00000002833	ENSOMEP00000020966	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Ribosomal protein S27a.	0.999
ENSOMEP00000002833	ENSOMEP00000024089	ENSOMEP00000002833	ENSOMEP00000024089	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Uncharacterized protein.	0.806
ENSOMEP00000002833	ENSOMEP00000025203	ENSOMEP00000002833	ENSOMEP00000025203	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Proteasome 26S subunit, non-ATPase 4b.	0.959
ENSOMEP00000002833	ENSOMEP00000026336	ENSOMEP00000002833	ENSOMEP00000026336	Ubiquitin A-52 residue ribosomal protein fusion product 1.	PROTEASOME_ALPHA_1 domain-containing protein.	0.933
ENSOMEP00000002833	ENSOMEP00000026888	ENSOMEP00000002833	ENSOMEP00000026888	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Proteasome 26S subunit, non-ATPase 5.	0.678
ENSOMEP00000002833	ENSOMEP00000027783	ENSOMEP00000002833	ENSOMEP00000027783	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Proteasome subunit beta; Belongs to the peptidase T1B family.	0.974
ENSOMEP00000002833	ENSOMEP00000027927	ENSOMEP00000002833	ENSOMEP00000027927	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Ubiquitin-like domain-containing protein.	0.989
ENSOMEP00000002833	ENSOMEP00000028219	ENSOMEP00000002833	ENSOMEP00000028219	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Proteasome endopeptidase complex.	0.951
ENSOMEP00000002833	ENSOMEP00000030940	ENSOMEP00000002833	ENSOMEP00000030940	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Tyrosine-protein kinase.	0.583
ENSOMEP00000002833	ENSOMEP00000034008	ENSOMEP00000002833	ENSOMEP00000034008	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Proteasome subunit beta 9a.	0.889
ENSOMEP00000002833	ENSOMEP00000035400	ENSOMEP00000002833	ENSOMEP00000035400	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Ubiquitin-like domain-containing protein.	0.999
ENSOMEP00000002833	LOC112136178	ENSOMEP00000002833	ENSOMEP00000015483	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Proteasome subunit beta.	0.889
ENSOMEP00000002833	LOC112137393	ENSOMEP00000002833	ENSOMEP00000031971	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Proteasome subunit beta.	0.914
ENSOMEP00000002833	LOC112137399	ENSOMEP00000002833	ENSOMEP00000031974	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Proteasome subunit beta.	0.931
ENSOMEP00000002833	LOC112137408	ENSOMEP00000002833	ENSOMEP00000031958	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Proteasome subunit beta 12.	0.889