STRINGSTRING
TGFBR2 TGFBR2 LOC112159397 LOC112159397 kxd1 kxd1 ENSOMEP00000027927 ENSOMEP00000027927 furin furin ENSOMEP00000029314 ENSOMEP00000029314 ENSOMEP00000029448 ENSOMEP00000029448 strap strap ENSOMEP00000030424 ENSOMEP00000030424 LOC112155766 LOC112155766 cbl cbl LOC112143591 LOC112143591 ENSOMEP00000032745 ENSOMEP00000032745 ltbp1 ltbp1 ltbp2 ltbp2 LOC112148478 LOC112148478 SMAD3-2 SMAD3-2 LOC112149681 LOC112149681 TGFB3 TGFB3 LOC112152993 LOC112152993 stub1 stub1 itgb8 itgb8 ENSOMEP00000011622 ENSOMEP00000011622 ENSOMEP00000011614 ENSOMEP00000011614 ENSOMEP00000011604 ENSOMEP00000011604 ENSOMEP00000011579 ENSOMEP00000011579 FBN1 FBN1 LOC112139043 LOC112139043 SMAD3 SMAD3 smad7 smad7 ENSOMEP00000005837 ENSOMEP00000005837 ENSOMEP00000034858 ENSOMEP00000034858 ENSOMEP00000035400 ENSOMEP00000035400 ldlrad4 ldlrad4 LOC112155588 LOC112155588 LOC112154448 LOC112154448 ENSOMEP00000002833 ENSOMEP00000002833 LOC112159231 LOC112159231 LOC112161061 LOC112161061 LOC112142874 LOC112142874 fkbp1b fkbp1b smad2 smad2 tgfb3 tgfb3 bambi bambi itgb5 itgb5 zfyve9 zfyve9 LOC112146702 LOC112146702 LOC112149754 LOC112149754 ENSOMEP00000020966 ENSOMEP00000020966 LOC112148176 LOC112148176 LOC112145260 LOC112145260 LTBP3 LTBP3 ENSOMEP00000023058 ENSOMEP00000023058 LOC112136593 LOC112136593
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LOC112159397Peptidylprolyl isomerase. (108 aa)
kxd1KxDL motif containing 1. (195 aa)
ENSOMEP00000027927Ubiquitin-like domain-containing protein. (77 aa)
furinFurin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (835 aa)
ENSOMEP00000029314Uncharacterized protein. (271 aa)
ENSOMEP00000029448NEDD8 ubiquitin like modifier. (94 aa)
strapSerine/threonine kinase receptor associated protein. (329 aa)
ENSOMEP00000030424Integrin beta; Belongs to the integrin beta chain family. (754 aa)
LOC112155766NEDD8 ubiquitin like modifier. (80 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (942 aa)
LOC112143591Cbl proto-oncogene C, E3 ubiquitin protein ligase. (560 aa)
ENSOMEP00000032745MH1 domain-containing protein. (63 aa)
ltbp1Latent transforming growth factor beta binding protein 1. (1398 aa)
ltbp2Uncharacterized protein. (1979 aa)
LOC112148478Mothers against decapentaplegic homolog. (467 aa)
SMAD3-2Mothers against decapentaplegic homolog. (429 aa)
LOC112149681Uncharacterized protein. (1677 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
LOC112152993Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
stub1STIP1 homology and U-Box containing protein 1. (284 aa)
itgb8Integrin beta; Belongs to the integrin beta chain family. (742 aa)
ENSOMEP00000011622Uncharacterized protein. (595 aa)
ENSOMEP00000011614EGF-like domain-containing protein. (46 aa)
ENSOMEP00000011604EGF-like domain-containing protein. (85 aa)
ENSOMEP00000011579Uncharacterized protein. (247 aa)
FBN1Fibrillin 1. (2877 aa)
LOC112139043Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
smad7Mothers against decapentaplegic homolog. (375 aa)
ENSOMEP00000005837Uncharacterized protein. (261 aa)
ENSOMEP00000034858Integrin beta; Belongs to the integrin beta chain family. (395 aa)
ENSOMEP00000035400Ubiquitin-like domain-containing protein. (137 aa)
ldlrad4Low density lipoprotein receptor class A domain containing 4b. (296 aa)
LOC112155588TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (574 aa)
LOC112154448Integrin beta; Belongs to the integrin beta chain family. (825 aa)
ENSOMEP00000002833Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
LOC112159231Peptidylprolyl isomerase. (109 aa)
LOC112161061Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (810 aa)
LOC112142874Uncharacterized protein. (856 aa)
fkbp1bPeptidylprolyl isomerase. (113 aa)
smad2Mothers against decapentaplegic homolog. (473 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (406 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
itgb5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
zfyve9Zinc finger, FYVE domain containing 9a. (1164 aa)
LOC112146702Integrin beta; Belongs to the integrin beta chain family. (783 aa)
LOC112149754Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
ENSOMEP00000020966Ribosomal protein S27a. (183 aa)
LOC112148176Mothers against decapentaplegic homolog. (510 aa)
LOC112145260Uncharacterized protein. (324 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1242 aa)
ENSOMEP00000023058Mothers against decapentaplegic homolog. (493 aa)
LOC112136593Mothers against decapentaplegic homolog. (536 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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