STRINGSTRING
arpc4 arpc4 ENSOMEP00000000402 ENSOMEP00000000402 fndc3a fndc3a PAK3 PAK3 YES1 YES1 was was LOC112158419 LOC112158419 CDC42 CDC42 arpc2 arpc2 LOC112150448 LOC112150448 grin2b grin2b ENSOMEP00000025561 ENSOMEP00000025561 LOC112162615 LOC112162615 LOC112155750 LOC112155750 LOC112158338 LOC112158338 ENSOMEP00000022476 ENSOMEP00000022476 LOC112144774 LOC112144774 actr2 actr2 LOC112147554 LOC112147554 LOC112162269 LOC112162269 cfl2 cfl2 FMN1 FMN1 hras hras LOC112155310 LOC112155310 cfl1 cfl1 LOC112138020 LOC112138020 LOC112144201 LOC112144201 rasa1 rasa1 rock1 rock1 ENSOMEP00000008609 ENSOMEP00000008609 ENSOMEP00000009022 ENSOMEP00000009022 ENSOMEP00000009907 ENSOMEP00000009907 ACTR3 ACTR3 LOC112143725 LOC112143725 src src LOC112146402 LOC112146402 efnb1 efnb1 LOC112144920 LOC112144920 LOC112138175 LOC112138175 LOC112138173 LOC112138173 LOC112142610 LOC112142610 LOC112163519 LOC112163519 ENSOMEP00000013530 ENSOMEP00000013530 LOC112158705 LOC112158705 LOC112137131 LOC112137131 ENSOMEP00000014715 ENSOMEP00000014715 ENSOMEP00000014363 ENSOMEP00000014363 ENSOMEP00000014358 ENSOMEP00000014358 pak1 pak1 LOC112139281 LOC112139281 LOC112152891 LOC112152891 arpc3 arpc3 LOC112137612 LOC112137612 arpc1a arpc1a LOC112137204 LOC112137204 ENSOMEP00000033157 ENSOMEP00000033157 LOC112160940 LOC112160940 LOC112156140 LOC112156140 ENSOMEP00000031576 ENSOMEP00000031576 ENSOMEP00000031327 ENSOMEP00000031327 LOC112148930 LOC112148930 actb actb arpc5 arpc5 ENSOMEP00000029915 ENSOMEP00000029915 LOC112147393 LOC112147393 ENSOMEP00000028145 ENSOMEP00000028145
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
arpc4Actin related protein 2/3 complex, subunit 4. (213 aa)
ENSOMEP00000000402Uncharacterized protein; Belongs to the actin family. (425 aa)
fndc3aFibronectin type III domain containing 3A. (1238 aa)
PAK3Non-specific serine/threonine protein kinase. (576 aa)
YES1Tyrosine-protein kinase. (552 aa)
wasUncharacterized protein. (528 aa)
LOC112158419Tyrosine-protein kinase. (528 aa)
CDC42Cell division cycle 42. (191 aa)
arpc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (299 aa)
LOC112150448Uncharacterized protein. (1027 aa)
grin2bUncharacterized protein. (1700 aa)
ENSOMEP00000025561Uncharacterized protein. (462 aa)
LOC112162615Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (209 aa)
LOC112155750Ephrin-B3a; Belongs to the ephrin family. (340 aa)
LOC112158338Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (362 aa)
ENSOMEP00000022476T cell lymphoma invasion and metastasis 1b. (1574 aa)
LOC112144774Cell division cycle 42. (191 aa)
actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
LOC112147554EPH receptor B1. (1007 aa)
LOC112162269ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (159 aa)
cfl2Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (217 aa)
FMN1Formin 1. (1117 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC112155310Ephrin-B2a; Belongs to the ephrin family. (334 aa)
cfl1Cofilin 1; Belongs to the actin-binding proteins ADF family. (167 aa)
LOC112138020Uncharacterized protein; Belongs to the actin family. (422 aa)
LOC112144201Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (150 aa)
rasa1RAS p21 protein activator (GTPase activating protein) 1a. (1053 aa)
rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1380 aa)
ENSOMEP00000008609FH2 domain-containing protein. (351 aa)
ENSOMEP00000009022Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
ENSOMEP00000009907Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (157 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
LOC112143725Uncharacterized protein. (191 aa)
srcTyrosine-protein kinase. (550 aa)
LOC112146402Tyrosine-protein kinase. (537 aa)
efnb1Ephrin-B1; Belongs to the ephrin family. (331 aa)
LOC112144920Eph receptor B2b. (1058 aa)
LOC112138175Uncharacterized protein. (375 aa)
LOC112138173Uncharacterized protein. (377 aa)
LOC112142610T cell lymphoma invasion and metastasis 1a. (1634 aa)
LOC112163519Glutamate receptor, ionotropic, N-methyl D-aspartate 1a. (964 aa)
ENSOMEP00000013530LITAF domain-containing protein. (127 aa)
LOC112158705Tyrosine-protein kinase. (551 aa)
LOC112137131Uncharacterized protein. (191 aa)
ENSOMEP00000014715Intersectin 1 (SH3 domain protein). (1093 aa)
ENSOMEP00000014363Protein kinase domain-containing protein. (107 aa)
ENSOMEP00000014358SAM domain-containing protein. (167 aa)
pak1Non-specific serine/threonine protein kinase. (568 aa)
LOC112139281Uncharacterized protein. (176 aa)
LOC112152891ADF-H domain-containing protein. (155 aa)
arpc3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
LOC112137612Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (381 aa)
arpc1aActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
LOC112137204Actin, beta 1. (375 aa)
ENSOMEP00000033157Uncharacterized protein. (87 aa)
LOC112160940Ephrin RBD domain-containing protein; Belongs to the ephrin family. (329 aa)
LOC112156140Zgc:101810; Belongs to the actin family. (394 aa)
ENSOMEP00000031576Fibronectin type III domain containing 3Ba. (1233 aa)
ENSOMEP00000031327Glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b. (1579 aa)
LOC112148930Uncharacterized protein. (939 aa)
actbActin beta. (375 aa)
arpc5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (150 aa)
ENSOMEP00000029915FH2 domain-containing protein. (375 aa)
LOC112147393Tyrosine-protein kinase. (547 aa)
ENSOMEP00000028145WH1 domain-containing protein. (188 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.