STRINGSTRING
ENSOMEP00000020966 ENSOMEP00000020966 LOC112139315 LOC112139315 fnbp4 fnbp4 ENSOMEP00000021678 ENSOMEP00000021678 map3k7 map3k7 LOC112161471 LOC112161471 LOC112151810 LOC112151810 ppp2ca ppp2ca traf6 traf6 ripk2 ripk2 LOC112153234 LOC112153234 ENSOMEP00000025532 ENSOMEP00000025532 LOC112159710 LOC112159710 MAP2K6 MAP2K6 LOC112142814 LOC112142814 ENSOMEP00000026569 ENSOMEP00000026569 ENSOMEP00000026618 ENSOMEP00000026618 ppp2cb ppp2cb mapk8 mapk8 kxd1 kxd1 map2k7 map2k7 nod1 nod1 MAPKAPK3 MAPKAPK3 ENSOMEP00000027927 ENSOMEP00000027927 ube2n ube2n ENSOMEP00000028804 ENSOMEP00000028804 ENSOMEP00000029714 ENSOMEP00000029714 LOC112146279 LOC112146279 LOC112147448 LOC112147448 ENSOMEP00000033551 ENSOMEP00000033551 LOC112154201 LOC112154201 LOC112153869 LOC112153869 ENSOMEP00000035400 ENSOMEP00000035400 ppp4r4 ppp4r4 ENSOMEP00000035932 ENSOMEP00000035932 ENSOMEP00000036077 ENSOMEP00000036077 LOC112144491 LOC112144491 ENSOMEP00000000883 ENSOMEP00000000883 vrk3 vrk3 ENSOMEP00000001754 ENSOMEP00000001754 ENSOMEP00000002833 ENSOMEP00000002833 LOC112161131 LOC112161131 ENSOMEP00000003380 ENSOMEP00000003380 map3k20 map3k20 LOC112144196 LOC112144196 atf2 atf2 dusp6 dusp6 mapk1 mapk1 fosl2 fosl2 LOC112156701 LOC112156701 ikbkg ikbkg ENSOMEP00000009829 ENSOMEP00000009829 ENSOMEP00000009965 ENSOMEP00000009965 LOC112146697 LOC112146697 tab2 tab2 ENSOMEP00000010628 ENSOMEP00000010628 ppp4r1 ppp4r1 tab3 tab3 LOC112156702 LOC112156702 relch relch ENSOMEP00000013464 ENSOMEP00000013464 LOC112155243 LOC112155243 tab1 tab1 LOC112146278 LOC112146278 LOC112159861 LOC112159861 ENSOMEP00000017683 ENSOMEP00000017683 mapk7 mapk7 dusp7 dusp7 MAPKAPK2 MAPKAPK2 LOC112158855 LOC112158855 ENSOMEP00000018942 ENSOMEP00000018942 LOC112158236 LOC112158236 ENSOMEP00000019194 ENSOMEP00000019194
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSOMEP00000020966Ribosomal protein S27a. (183 aa)
LOC112139315Mitogen-activated protein kinase. (361 aa)
fnbp4Formin binding protein 4. (870 aa)
ENSOMEP00000021678Protein kinase domain-containing protein. (528 aa)
map3k7Mitogen-activated protein kinase kinase kinase 7. (595 aa)
LOC112161471Mitogen-activated protein kinase. (438 aa)
LOC112151810Uncharacterized protein. (316 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
ripk2Receptor-interacting serine-threonine kinase 2. (589 aa)
LOC112153234Mitogen-activated protein kinase. (420 aa)
ENSOMEP00000025532Mitogen-activated protein kinase. (402 aa)
LOC112159710Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (359 aa)
MAP2K6Mitogen-activated protein kinase kinase 6. (361 aa)
LOC112142814Ribosomal protein S6 kinase. (787 aa)
ENSOMEP00000026569Activating transcription factor 1. (253 aa)
ENSOMEP00000026618Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (474 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
mapk8Mitogen-activated protein kinase. (384 aa)
kxd1KxDL motif containing 1. (195 aa)
map2k7Mitogen-activated protein kinase kinase 7. (423 aa)
nod1Nucleotide-binding oligomerization domain containing 1. (1032 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (415 aa)
ENSOMEP00000027927Ubiquitin-like domain-containing protein. (77 aa)
ube2nUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
ENSOMEP00000028804ETS transcription factor ELK1. (487 aa)
ENSOMEP00000029714Protein kinase domain-containing protein. (102 aa)
LOC112146279Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (423 aa)
LOC112147448Protein kinase domain-containing protein. (667 aa)
ENSOMEP00000033551Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
LOC112154201Mitogen-activated protein kinase kinase 6. (358 aa)
LOC112153869Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (495 aa)
ENSOMEP00000035400Ubiquitin-like domain-containing protein. (137 aa)
ppp4r4Protein phosphatase 4, regulatory subunit 4. (901 aa)
ENSOMEP00000035932Mitogen-activated protein kinase. (351 aa)
ENSOMEP00000036077Ribosomal protein S6 kinase. (736 aa)
LOC112144491Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (397 aa)
ENSOMEP00000000883Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (294 aa)
vrk3VRK serine/threonine kinase 3. (513 aa)
ENSOMEP00000001754UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
ENSOMEP00000002833Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
LOC112161131Ribosomal protein S6 kinase. (746 aa)
ENSOMEP00000003380Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (192 aa)
map3k20Uncharacterized protein. (799 aa)
LOC112144196JunE proto-oncogene, AP-1 transcription factor subunit. (348 aa)
atf2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa)
dusp6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
fosl2Fos-like antigen 2. (345 aa)
LOC112156701UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
ikbkgInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (585 aa)
ENSOMEP00000009829Non-specific serine/threonine protein kinase. (592 aa)
ENSOMEP00000009965Protein kinase domain-containing protein. (546 aa)
LOC112146697Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (215 aa)
tab2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (733 aa)
ENSOMEP00000010628Mitogen-activated protein kinase 15. (529 aa)
ppp4r1WRNPLPNID domain-containing protein. (964 aa)
tab3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (601 aa)
LOC112156702cAMP responsive element binding protein 1. (340 aa)
relchRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1187 aa)
ENSOMEP00000013464Protein phosphatase 2, regulatory subunit A, beta b. (647 aa)
LOC112155243cAMP responsive element binding protein 1b. (328 aa)
tab1TGF-beta activated kinase 1/MAP3K7 binding protein 1. (504 aa)
LOC112146278Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (389 aa)
LOC112159861Uncharacterized protein. (525 aa)
ENSOMEP00000017683BZIP domain-containing protein. (135 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1061 aa)
dusp7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
MAPKAPK2MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (384 aa)
LOC112158855Mitogen-activated protein kinase. (360 aa)
ENSOMEP00000018942Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (485 aa)
LOC112158236V-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (458 aa)
ENSOMEP00000019194V-fos FBJ murine osteosarcoma viral oncogene homolog Aa. (416 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.