41 items (Oryzias melastigma) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC112143591	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (560 aa)
	pik3r1	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
	LOC112159720	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (942 aa)
	LOC112162969	Rap guanine nucleotide exchange factor (GEF) 1b. (1203 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC112147393	Tyrosine-protein kinase. (547 aa)
	LOC112138447	Uncharacterized protein. (716 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)
	jak1	Tyrosine-protein kinase. (1173 aa)
	ENSOMEP00000025667	Spleen tyrosine kinase. (341 aa)
	LOC112147412	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	ENSOMEP00000024195	Uncharacterized protein. (484 aa)
	LOC112163270	Tyrosine-protein kinase. (1131 aa)
	ENSOMEP00000020966	Ribosomal protein S27a. (183 aa)
	pik3cd	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa)
	LOC112150124	Tyrosine-protein kinase. (1112 aa)
	blk	Tyrosine-protein kinase. (487 aa)
	pik3r3	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (723 aa)
	LOC112146402	Tyrosine-protein kinase. (537 aa)
	ENSOMEP00000011997	Tyrosine-protein kinase. (1090 aa)
	ENSOMEP00000011943	Protein tyrosine phosphatase non-receptor type 6. (557 aa)
	LOC112147562	Uncharacterized protein. (466 aa)
	hck	Tyrosine-protein kinase. (504 aa)
	SHC4	SHC adaptor protein 4. (494 aa)
	ENSOMEP00000006129	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1078 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (588 aa)
	rapgef1	Uncharacterized protein. (884 aa)
	ENSOMEP00000002833	Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
	LOC112158419	Tyrosine-protein kinase. (528 aa)
	ENSOMEP00000002349	Uncharacterized protein. (585 aa)
	YES1	Tyrosine-protein kinase. (552 aa)
	LOC112142874	Uncharacterized protein. (856 aa)
	LOC112143053	Uncharacterized protein. (313 aa)
	gab2	GRB2-associated binding protein 2. (674 aa)
	LOC112142636	Inositol polyphosphate phosphatase-like 1b. (1221 aa)
	LOC112149634	CRK proto-oncogene, adaptor protein. (313 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (306 aa)
	LOC112146542	Uncharacterized protein. (685 aa)
	ENSOMEP00000035400	Ubiquitin-like domain-containing protein. (137 aa)
	ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000002349	ENSOMEP00000006129	ENSOMEP00000002349	ENSOMEP00000006129	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.975
ENSOMEP00000002349	ENSOMEP00000011943	ENSOMEP00000002349	ENSOMEP00000011943	Uncharacterized protein.	Protein tyrosine phosphatase non-receptor type 6.	0.732
ENSOMEP00000002349	ENSOMEP00000011997	ENSOMEP00000002349	ENSOMEP00000011997	Uncharacterized protein.	Tyrosine-protein kinase.	0.583
ENSOMEP00000002349	ENSOMEP00000024195	ENSOMEP00000002349	ENSOMEP00000024195	Uncharacterized protein.	Uncharacterized protein.	0.441
ENSOMEP00000002349	ENSOMEP00000025667	ENSOMEP00000002349	ENSOMEP00000025667	Uncharacterized protein.	Spleen tyrosine kinase.	0.675
ENSOMEP00000002349	LOC112138447	ENSOMEP00000002349	ENSOMEP00000027004	Uncharacterized protein.	Uncharacterized protein.	0.893
ENSOMEP00000002349	LOC112142636	ENSOMEP00000002349	ENSOMEP00000032145	Uncharacterized protein.	Inositol polyphosphate phosphatase-like 1b.	0.908
ENSOMEP00000002349	LOC112142874	ENSOMEP00000002349	ENSOMEP00000001613	Uncharacterized protein.	Uncharacterized protein.	0.760
ENSOMEP00000002349	LOC112143053	ENSOMEP00000002349	ENSOMEP00000001359	Uncharacterized protein.	Uncharacterized protein.	0.707
ENSOMEP00000002349	LOC112143591	ENSOMEP00000002349	ENSOMEP00000031882	Uncharacterized protein.	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	0.760
ENSOMEP00000002349	LOC112146402	ENSOMEP00000002349	ENSOMEP00000012176	Uncharacterized protein.	Tyrosine-protein kinase.	0.590
ENSOMEP00000002349	LOC112147393	ENSOMEP00000002349	ENSOMEP00000028263	Uncharacterized protein.	Tyrosine-protein kinase.	0.716
ENSOMEP00000002349	LOC112147412	ENSOMEP00000002349	ENSOMEP00000025220	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.975
ENSOMEP00000002349	LOC112147562	ENSOMEP00000002349	ENSOMEP00000008792	Uncharacterized protein.	Uncharacterized protein.	0.894
ENSOMEP00000002349	LOC112149634	ENSOMEP00000002349	ENSOMEP00000034158	Uncharacterized protein.	CRK proto-oncogene, adaptor protein.	0.707
ENSOMEP00000002349	LOC112150124	ENSOMEP00000002349	ENSOMEP00000017393	Uncharacterized protein.	Tyrosine-protein kinase.	0.583
ENSOMEP00000002349	LOC112158419	ENSOMEP00000002349	ENSOMEP00000002696	Uncharacterized protein.	Tyrosine-protein kinase.	0.590
ENSOMEP00000002349	LOC112159720	ENSOMEP00000002349	ENSOMEP00000031214	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.732
ENSOMEP00000002349	LOC112162969	ENSOMEP00000002349	ENSOMEP00000028383	Uncharacterized protein.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.416
ENSOMEP00000002349	LOC112163270	ENSOMEP00000002349	ENSOMEP00000021676	Uncharacterized protein.	Tyrosine-protein kinase.	0.583