33 items (Oryzias melastigma) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fndc3a	Fibronectin type III domain containing 3A. (1238 aa)
	LOC112142874	Uncharacterized protein. (856 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	LOC112150729	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	ENSOMEP00000002833	Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
	LOC112153795	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
	fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (268 aa)
	mknk1	MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (457 aa)
	ENSOMEP00000006056	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (201 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	src	Tyrosine-protein kinase. (550 aa)
	ENSOMEP00000013464	Protein phosphatase 2, regulatory subunit A, beta b. (647 aa)
	frs2	Fibroblast growth factor receptor substrate 2b. (525 aa)
	LOC112153328	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
	LOC112158705	Tyrosine-protein kinase. (551 aa)
	LOC112146278	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (389 aa)
	ENSOMEP00000020966	Ribosomal protein S27a. (183 aa)
	ENSOMEP00000021196	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	LOC112151134	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	fgf23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (257 aa)
	spry2	Sprouty RTK signaling antagonist 2. (417 aa)
	mknk2	MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (476 aa)
	fgf16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
	LOC112137449	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (269 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (942 aa)
	ENSOMEP00000031576	Fibronectin type III domain containing 3Ba. (1233 aa)
	LOC112143591	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (560 aa)
	ENSOMEP00000031976	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
	ENSOMEP00000035400	Ubiquitin-like domain-containing protein. (137 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000002833	ENSOMEP00000006056	ENSOMEP00000002833	ENSOMEP00000006056	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.606
ENSOMEP00000002833	ENSOMEP00000013464	ENSOMEP00000002833	ENSOMEP00000013464	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Protein phosphatase 2, regulatory subunit A, beta b.	0.667
ENSOMEP00000002833	ENSOMEP00000020966	ENSOMEP00000002833	ENSOMEP00000020966	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Ribosomal protein S27a.	0.999
ENSOMEP00000002833	ENSOMEP00000021196	ENSOMEP00000002833	ENSOMEP00000021196	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.631
ENSOMEP00000002833	ENSOMEP00000031576	ENSOMEP00000002833	ENSOMEP00000031576	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Fibronectin type III domain containing 3Ba.	0.497
ENSOMEP00000002833	ENSOMEP00000031976	ENSOMEP00000002833	ENSOMEP00000031976	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.626
ENSOMEP00000002833	ENSOMEP00000035400	ENSOMEP00000002833	ENSOMEP00000035400	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Ubiquitin-like domain-containing protein.	0.999
ENSOMEP00000002833	LOC112137449	ENSOMEP00000002833	ENSOMEP00000025940	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.581
ENSOMEP00000002833	LOC112142874	ENSOMEP00000002833	ENSOMEP00000001613	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Uncharacterized protein.	0.861
ENSOMEP00000002833	LOC112143591	ENSOMEP00000002833	ENSOMEP00000031882	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	0.861
ENSOMEP00000002833	LOC112146278	ENSOMEP00000002833	ENSOMEP00000016922	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.634
ENSOMEP00000002833	LOC112150729	ENSOMEP00000002833	ENSOMEP00000002474	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.606
ENSOMEP00000002833	LOC112151134	ENSOMEP00000002833	ENSOMEP00000021956	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.620
ENSOMEP00000002833	LOC112153328	ENSOMEP00000002833	ENSOMEP00000013856	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.581
ENSOMEP00000002833	LOC112153795	ENSOMEP00000002833	ENSOMEP00000002985	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.606
ENSOMEP00000002833	LOC112158705	ENSOMEP00000002833	ENSOMEP00000015391	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Tyrosine-protein kinase.	0.583
ENSOMEP00000002833	cbl	ENSOMEP00000002833	ENSOMEP00000031146	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.861
ENSOMEP00000002833	fgf1	ENSOMEP00000002833	ENSOMEP00000004387	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.606
ENSOMEP00000002833	fgf16	ENSOMEP00000002833	ENSOMEP00000025855	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.581
ENSOMEP00000002833	fgf2	ENSOMEP00000002833	ENSOMEP00000023264	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.480