STRINGSTRING
FGF6-2 FGF6-2 ENSOMEP00000035571 ENSOMEP00000035571 LOC112155731 LOC112155731 ENSOMEP00000000731 ENSOMEP00000000731 fndc3a fndc3a LOC112142874 LOC112142874 fgf4 fgf4 ENSOMEP00000002153 ENSOMEP00000002153 LOC112150729 LOC112150729 ENSOMEP00000002833 ENSOMEP00000002833 LOC112153795 LOC112153795 gab1 gab1 FGF6 FGF6 fgf1 fgf1 FGFRL1 FGFRL1 ENSOMEP00000005379 ENSOMEP00000005379 mknk1 mknk1 LOC112150859 LOC112150859 shc1 shc1 ENSOMEP00000006056 ENSOMEP00000006056 ANOS1 ANOS1 LOC112142816 LOC112142816 LOC112143453 LOC112143453 mapk1 mapk1 SHC4 SHC4 KRAS KRAS src src LOC112158056 LOC112158056 ENSOMEP00000013464 ENSOMEP00000013464 frs2 frs2 LOC112153328 LOC112153328 LOC112148278 LOC112148278 LOC112158705 LOC112158705 LOC112146278 LOC112146278 hras hras LOC112153506 LOC112153506 LOC112149208 LOC112149208 ENSOMEP00000035400 ENSOMEP00000035400 ENSOMEP00000031976 ENSOMEP00000031976 LOC112143591 LOC112143591 LOC112146394 LOC112146394 ENSOMEP00000031576 ENSOMEP00000031576 ENSOMEP00000031391 ENSOMEP00000031391 cbl cbl CSDE1 CSDE1 spred1 spred1 plcg1 plcg1 LOC112153728 LOC112153728 PIK3CA PIK3CA ppp2cb ppp2cb grb2 grb2 fgf22 fgf22 LOC112137449 LOC112137449 LOC112147412 LOC112147412 mknk2 mknk2 spry2 spry2 fgf23 fgf23 ppp2ca ppp2ca fgf2 fgf2 LOC112151134 LOC112151134 spred2 spred2 ENSOMEP00000021196 ENSOMEP00000021196 ENSOMEP00000020966 ENSOMEP00000020966 flrt3 flrt3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSOMEP00000035571Uncharacterized protein. (95 aa)
LOC112155731PH domain-containing protein. (737 aa)
ENSOMEP00000000731Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
fndc3aFibronectin type III domain containing 3A. (1238 aa)
LOC112142874Uncharacterized protein. (856 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
ENSOMEP00000002153Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (240 aa)
LOC112150729Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
ENSOMEP00000002833Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
LOC112153795Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
gab1GRB2-associated binding protein 1. (762 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (198 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (268 aa)
FGFRL1Fibroblast growth factor receptor like 1. (507 aa)
ENSOMEP00000005379Fibroblast growth factor receptor substrate 3. (606 aa)
mknk1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (457 aa)
LOC112150859Uncharacterized protein. (753 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (588 aa)
ENSOMEP00000006056Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (201 aa)
ANOS1Anosmin 1. (673 aa)
LOC112142816Fibronectin leucine rich transmembrane protein 1. (685 aa)
LOC112143453Sprouty related EVH1 domain containing 2a. (427 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
SHC4SHC adaptor protein 4. (494 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
srcTyrosine-protein kinase. (550 aa)
LOC112158056Fibronectin leucine rich transmembrane protein 2. (658 aa)
ENSOMEP00000013464Protein phosphatase 2, regulatory subunit A, beta b. (647 aa)
frs2Fibroblast growth factor receptor substrate 2b. (525 aa)
LOC112153328Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
LOC112148278Fibroblast growth factor receptor. (831 aa)
LOC112158705Tyrosine-protein kinase. (551 aa)
LOC112146278Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (389 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC112153506Fibronectin leucine rich transmembrane protein 1b. (729 aa)
LOC112149208Fibronectin leucine rich transmembrane protein 2. (653 aa)
ENSOMEP00000035400Ubiquitin-like domain-containing protein. (137 aa)
ENSOMEP00000031976Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
LOC112143591Cbl proto-oncogene C, E3 ubiquitin protein ligase. (560 aa)
LOC112146394Zgc:55558. (186 aa)
ENSOMEP00000031576Fibronectin type III domain containing 3Ba. (1233 aa)
ENSOMEP00000031391Fibroblast growth factor 10b; Belongs to the heparin-binding growth factors family. (70 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (942 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (869 aa)
spred1Sprouty related EVH1 domain containing 1. (443 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
LOC112153728Fibroblast growth factor receptor like 1a. (526 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC112137449Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (269 aa)
LOC112147412Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (476 aa)
spry2Sprouty RTK signaling antagonist 2. (417 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (257 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa)
LOC112151134Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
spred2Sprouty related EVH1 domain containing 2. (467 aa)
ENSOMEP00000021196Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
ENSOMEP00000020966Ribosomal protein S27a. (183 aa)
flrt3Fibronectin leucine rich transmembrane 3. (650 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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