Your Input: | |
| | ENSOMEP00000020966 | Ribosomal protein S27a. (183 aa) |
| | ENSOMEP00000021087 | ANK_REP_REGION domain-containing protein. (663 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (527 aa) |
| | ENSOMEP00000021629 | RecQ helicase-like 4. (991 aa) |
| | rmi2 | RecQ mediated genome instability 2. (140 aa) |
| | ENSOMEP00000021991 | RECA_2 domain-containing protein. (275 aa) |
| | lig3 | DNA ligase. (1009 aa) |
| | xrcc5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (725 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa) |
| | ENSOMEP00000023373 | DNA ligase. (690 aa) |
| | ENSOMEP00000023460 | Uncharacterized protein. (85 aa) |
| | rhno1 | Si:ch73-352p4.5. (261 aa) |
| | cdca7 | Cell division cycle associated 7a. (448 aa) |
| | LOC112159308 | Uncharacterized protein. (383 aa) |
| | pold3 | Polymerase (DNA-directed), delta 3, accessory subunit. (438 aa) |
| | LOC112149564 | BRCA2 DNA repair associated. (2893 aa) |
| | kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (558 aa) |
| | rcbtb2 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (547 aa) |
| | uimc1 | Uncharacterized protein. (838 aa) |
| | ENSOMEP00000000824 | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (498 aa) |
| | ENSOMEP00000000668 | DNA topoisomerase II binding protein 1. (1377 aa) |
| | ENSOMEP00000000665 | Reverse transcriptase domain-containing protein. (964 aa) |
| | rad51d | RAD51 paralog D. (358 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (283 aa) |
| | ppp4r2 | Protein phosphatase 4, regulatory subunit 2b. (418 aa) |
| | exo1 | Exonuclease 1. (757 aa) |
| | ENSOMEP00000000016 | Reverse transcriptase domain-containing protein. (913 aa) |
| | kxd1 | KxDL motif containing 1. (195 aa) |
| | eya1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (608 aa) |
| | rad52 | RAD52 homolog, DNA repair protein. (418 aa) |
| | pole4 | Polymerase (DNA-directed), epsilon 4, accessory subunit. (148 aa) |
| | babam2 | BRISC and BRCA1 A complex member 2. (386 aa) |
| | ENSOMEP00000026997 | BRCA1/BRCA2-containing complex, subunit 3. (262 aa) |
| | xrcc6 | X-ray repair complementing defective repair in Chinese hamster cells 6. (611 aa) |
| | ENSOMEP00000026824 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (98 aa) |
| | ENSOMEP00000026302 | Si:dkey-261m9.6; Belongs to the histone H2B family. (111 aa) |
| | rad1 | RAD1 homolog (S. pombe). (279 aa) |
| | rpa3 | Replication protein A3. (122 aa) |
| | SPIDR | Uncharacterized protein. (912 aa) |
| | xrcc4 | Uncharacterized protein. (300 aa) |
| | ENSOMEP00000025108 | Reverse transcriptase domain-containing protein. (792 aa) |
| | slx4 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1506 aa) |
| | LOC112156448 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (276 aa) |
| | ENSOMEP00000024413 | Abraxas 1, BRCA1 A complex subunit. (356 aa) |
| | ENSOMEP00000024355 | Uncharacterized protein. (981 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (647 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (664 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (627 aa) |
| | blm | BLM RecQ like helicase. (1368 aa) |
| | ENSOMEP00000035766 | Reverse transcriptase domain-containing protein. (1156 aa) |
| | LOC112157413 | DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (615 aa) |
| | polm | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (486 aa) |
| | ENSOMEP00000035472 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (348 aa) |
| | ENSOMEP00000035400 | Ubiquitin-like domain-containing protein. (137 aa) |
| | cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | ppp5c | Serine/threonine-protein phosphatase. (491 aa) |
| | rif1 | Replication timing regulatory factor 1. (2264 aa) |
| | xrcc1 | X-ray repair complementing defective repair in Chinese hamster cells 1. (620 aa) |
| | ENSOMEP00000034414 | Reverse transcriptase domain-containing protein. (1075 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa) |
| | LOC112150551 | Lysine (K)-specific demethylase 4B. (1255 aa) |
| | chek1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (455 aa) |
| | ENSOMEP00000033039 | Small ubiquitin-related modifier. (76 aa) |
| | ENSOMEP00000032934 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa) |
| | ENSOMEP00000032897 | Histone H2B; Belongs to the histone H2B family. (113 aa) |
| | ENSOMEP00000032839 | Histone H2B; Belongs to the histone H2B family. (115 aa) |
| | eme1 | Essential meiotic structure-specific endonuclease 1. (498 aa) |
| | pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) |
| | rpa2 | Replication protein A2. (270 aa) |
| | tdp1 | Tyrosyl-DNA phosphodiesterase 1. (615 aa) |
| | ENSOMEP00000031710 | Histone H2B; Belongs to the histone H2B family. (115 aa) |
| | eya4 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (642 aa) |
| | LOC112145672 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (476 aa) |
| | ube2i | Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | ENSOMEP00000031192 | Uncharacterized protein. (116 aa) |
| | ENSOMEP00000031175 | Endo/exonuclease/phosphatase domain-containing protein. (296 aa) |
| | nhej1 | Nonhomologous end-joining factor 1. (308 aa) |
| | tdrd3 | Tudor domain containing 3. (779 aa) |
| | LOC112153553 | Uncharacterized protein. (249 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (691 aa) |
| | sumo2 | Small ubiquitin-related modifier. (115 aa) |
| | ENSOMEP00000029974 | Reverse transcriptase domain-containing protein. (1319 aa) |
| | parp3 | Poly [ADP-ribose] polymerase. (530 aa) |
| | LOC112155690 | Small ubiquitin like modifier 3b. (137 aa) |
| | ENSOMEP00000029282 | AAA_23 domain-containing protein. (51 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (357 aa) |
| | ENSOMEP00000028980 | Tyrosyl-DNA phosphodiesterase 2b. (353 aa) |
| | ENSOMEP00000028916 | Replication factor C subunit 1. (1042 aa) |
| | ENSOMEP00000028815 | Replication factor C (activator 1) 3. (279 aa) |
| | ENSOMEP00000028590 | Uncharacterized protein. (106 aa) |
| | ENSOMEP00000028431 | RAD51 paralog C. (307 aa) |
| | ube2n | Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | ENSOMEP00000027927 | Ubiquitin-like domain-containing protein. (77 aa) |
| | gen1 | Uncharacterized protein. (852 aa) |
| | ENSOMEP00000027698 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa) |
| | tp53bp1 | Tumor protein p53 binding protein, 1. (1505 aa) |
| | pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2291 aa) |
| | ccna2 | Cyclin A2; Belongs to the cyclin family. (431 aa) |
| | paxip1 | PAX interacting (with transcription-activation domain) protein 1. (1104 aa) |
| | apbb1 | Amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65). (683 aa) |
| | ppp4c | Serine/threonine-protein phosphatase. (311 aa) |
| | baz1b | Bromodomain adjacent to zinc finger domain, 1B. (1608 aa) |
| | pole3 | Polymerase (DNA directed), epsilon 3 (p17 subunit). (147 aa) |
| | ENSOMEP00000002422 | MUS81 structure-specific endonuclease subunit. (514 aa) |
| | ENSOMEP00000002606 | Uncharacterized protein. (161 aa) |
| | abl1 | Tyrosine-protein kinase. (1083 aa) |
| | ENSOMEP00000002833 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa) |
| | smarca5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1036 aa) |
| | ENSOMEP00000003330 | RING-type domain-containing protein. (841 aa) |
| | nsd2 | Nuclear receptor binding SET domain protein 2. (1279 aa) |
| | ENSOMEP00000003507 | X-ray repair complementing defective repair in Chinese hamster cells 4. (329 aa) |
| | LOC112146732 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (598 aa) |
| | pias4 | Protein inhibitor of activated STAT, 4a. (503 aa) |
| | rad51ap1 | RAD51 associated protein 1. (313 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (376 aa) |
| | ENSOMEP00000004138 | TAN domain-containing protein. (176 aa) |
| | ENSOMEP00000004154 | Uncharacterized protein. (133 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1024 aa) |
| | eya3 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (574 aa) |
| | polk | Polymerase (DNA directed) kappa. (847 aa) |
| | ENSOMEP00000004644 | Polymerase (DNA directed), eta. (302 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1311 aa) |
| | nbn | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (827 aa) |
| | ube2v2 | Ubiquitin-conjugating enzyme E2 variant 2. (145 aa) |
| | slf1 | SMC5-SMC6 complex localization factor 1. (873 aa) |
| | meiob | Methionine sulfoxide reductase B1b. (461 aa) |
| | cnppd1 | Cyclin Pas1/PHO80 domain containing 1. (402 aa) |
| | ENSOMEP00000006493 | Reverse transcriptase domain-containing protein. (1265 aa) |
| | ENSOMEP00000006622 | Histone H2B; Belongs to the histone H2B family. (170 aa) |
| | ENSOMEP00000006627 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (149 aa) |
| | ENSOMEP00000006733 | PARP-type domain-containing protein. (104 aa) |
| | ENSOMEP00000006747 | Poly [ADP-ribose] polymerase. (395 aa) |
| | atrip | Uncharacterized protein. (739 aa) |
| | LOC112138059 | Histone H2B 1/2. (124 aa) |
| | ENSOMEP00000007189 | Reverse transcriptase domain-containing protein. (227 aa) |
| | LOC112159947 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (573 aa) |
| | ENSOMEP00000007389 | Importin subunit alpha; Belongs to the importin alpha family. (517 aa) |
| | ENSOMEP00000007665 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa) |
| | KPNA2 | Importin subunit alpha; Belongs to the importin alpha family. (533 aa) |
| | ENSOMEP00000008661 | BRCT domain-containing protein. (162 aa) |
| | ENSOMEP00000009159 | Histone H2B; Belongs to the histone H2B family. (110 aa) |
| | ENSOMEP00000009168 | Reverse transcriptase domain-containing protein. (962 aa) |
| | ENSOMEP00000009187 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa) |
| | LOC112156259 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (346 aa) |
| | ENSOMEP00000009479 | Uncharacterized protein; Belongs to the histone H2A family. (245 aa) |
| | LOC112156701 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | tmem182 | Transmembrane protein 182a. (238 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (649 aa) |
| | poll | Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (566 aa) |
| | ENSOMEP00000010830 | Replication factor C (activator 1) 5. (326 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (527 aa) |
| | ccna1 | Cyclin A1; Belongs to the cyclin family. (457 aa) |
| | ENSOMEP00000011219 | Uncharacterized protein. (96 aa) |
| | LOC112148474 | Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa) |
| | sirt7 | Sirtuin 7. (407 aa) |
| | polq | Polymerase (DNA directed), theta. (2616 aa) |
| | LOC112149581 | Histone H2A; Belongs to the histone H2A family. (138 aa) |
| | mdc1 | Uncharacterized protein. (1925 aa) |
| | ENSOMEP00000013312 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (145 aa) |
| | ENSOMEP00000013345 | Uncharacterized protein. (122 aa) |
| | pole2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (355 aa) |
| | ENSOMEP00000014230 | Zgc:110269. (346 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | rnf168 | RING-type domain-containing protein. (393 aa) |
| | ENSOMEP00000015130 | Histone H2B; Belongs to the histone H2B family. (114 aa) |
| | pold1 | DNA polymerase. (1105 aa) |
| | tipin | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (317 aa) |
| | rbbp8 | Uncharacterized protein. (614 aa) |
| | eme2 | ERCC4 domain-containing protein. (429 aa) |
| | ENSOMEP00000015819 | Protein kinase domain-containing protein. (358 aa) |
| | ENSOMEP00000016531 | Ubiquitin-like domain-containing protein. (201 aa) |
| | ankrd11 | Ankyrin repeat domain 11. (2829 aa) |
| | ENSOMEP00000016821 | Histone H2B; Belongs to the histone H2B family. (130 aa) |
| | ENSOMEP00000016897 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (101 aa) |
| | palb2 | PALB2_WD40 domain-containing protein. (1266 aa) |
| | sirt6 | Sirtuin 6. (347 aa) |
| | ankrd12 | Ankyrin repeat domain 12. (1899 aa) |
| | ENSOMEP00000019762 | Reverse transcriptase domain-containing protein. (1029 aa) |
| | ENSOMEP00000020156 | Uncharacterized protein. (127 aa) |
| | ENSOMEP00000020174 | Reverse transcriptase domain-containing protein. (460 aa) |
| | timeless | Timeless circadian clock. (1244 aa) |
| | ENSOMEP00000020858 | Poly [ADP-ribose] polymerase. (610 aa) |
