60 items (Oryzias melastigma) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSOMEP00000001450	Excision repair cross-complementation group 6. (1379 aa)
	POLR2E	RNA polymerase II subunit E. (210 aa)
	gps1	G protein pathway suppressor 1. (487 aa)
	LOC112137766	General transcription factor IIH subunit. (392 aa)
	ENSOMEP00000002833	Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
	LOC112146043	E1A binding protein p300 b. (2771 aa)
	ZNF830	Zinc finger protein 830. (323 aa)
	ENSOMEP00000005155	Damage-specific DNA binding protein 1. (1105 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	xpa	Xeroderma pigmentosum, complementation group A. (275 aa)
	ENSOMEP00000006794	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1244 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (460 aa)
	ENSOMEP00000007590	Protein phosphatase 1, regulatory subunit 42. (292 aa)
	cops5	COP9 signalosome subunit 5. (334 aa)
	LOC112153984	E1A binding protein p300 a. (2690 aa)
	tceanc	TFIIS central domain-containing protein. (311 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	cops3	COP9 signalosome subunit 3. (559 aa)
	ENSOMEP00000009552	Transcription elongation factor A (SII), 3. (383 aa)
	polr2i	Polymerase (RNA) II (DNA directed) polypeptide I. (137 aa)
	ENSOMEP00000011934	Uncharacterized protein. (67 aa)
	LOC112159719	Transcription elongation factor A (SII), 2. (309 aa)
	ENSOMEP00000014615	Cullin 4A; Belongs to the cullin family. (760 aa)
	ENSOMEP00000014790	Uncharacterized protein. (272 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (550 aa)
	cops8	COP9 signalosome subunit 8. (192 aa)
	polr2g	Polymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
	uvssa	UV-stimulated scaffold protein A. (762 aa)
	polr2l	Polymerase (RNA) II (DNA directed) polypeptide L. (68 aa)
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	ercc8	Excision repair cross-complementation group 8. (401 aa)
	ENSOMEP00000020966	Ribosomal protein S27a. (183 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	ENSOMEP00000021808	ISY1 splicing factor homolog. (281 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (300 aa)
	prpf19	Pre-mRNA processing factor 19. (505 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
	rbx1	Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (326 aa)
	ENSOMEP00000025354	Polymerase (RNA) II (DNA directed) polypeptide F. (169 aa)
	cops2	COP9 signalosome subunit 2. (443 aa)
	kxd1	KxDL motif containing 1. (195 aa)
	ENSOMEP00000027875	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1628 aa)
	tcea1	Transcription elongation factor A (SII), 1. (311 aa)
	ENSOMEP00000027927	Ubiquitin-like domain-containing protein. (77 aa)
	nrde2	NRDE-2, necessary for RNA interference, domain containing. (1199 aa)
	COPS6	COP9 signalosome subunit 6. (323 aa)
	tceanc2	Uncharacterized protein. (206 aa)
	aqr	Aquarius intron-binding spliceosomal factor. (1469 aa)
	COPS7B	COP9 signalosome subunit 7B. (291 aa)
	ppie	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (302 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (864 aa)
	ercc3	Excision repair cross-complementation group 3. (783 aa)
	cops4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (406 aa)
	polr2d	Polymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
	polr2c	Polymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
	ENSOMEP00000034450	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1117 aa)
	ENSOMEP00000035400	Ubiquitin-like domain-containing protein. (137 aa)
	xab2	XPA binding protein 2. (848 aa)
	polr2j	Polymerase (RNA) II (DNA directed) polypeptide J. (117 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPS6	COPS7B	ENSOMEP00000029118	ENSOMEP00000030187	COP9 signalosome subunit 6.	COP9 signalosome subunit 7B.	0.997
COPS6	ENSOMEP00000001450	ENSOMEP00000029118	ENSOMEP00000001450	COP9 signalosome subunit 6.	Excision repair cross-complementation group 6.	0.721
COPS6	ENSOMEP00000002833	ENSOMEP00000029118	ENSOMEP00000002833	COP9 signalosome subunit 6.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.906
COPS6	ENSOMEP00000005155	ENSOMEP00000029118	ENSOMEP00000005155	COP9 signalosome subunit 6.	Damage-specific DNA binding protein 1.	0.939
COPS6	ENSOMEP00000006794	ENSOMEP00000029118	ENSOMEP00000006794	COP9 signalosome subunit 6.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.750
COPS6	ENSOMEP00000007590	ENSOMEP00000029118	ENSOMEP00000007590	COP9 signalosome subunit 6.	Protein phosphatase 1, regulatory subunit 42.	0.987
COPS6	ENSOMEP00000009552	ENSOMEP00000029118	ENSOMEP00000009552	COP9 signalosome subunit 6.	Transcription elongation factor A (SII), 3.	0.441
COPS6	ENSOMEP00000011934	ENSOMEP00000029118	ENSOMEP00000011934	COP9 signalosome subunit 6.	Uncharacterized protein.	0.680
COPS6	ENSOMEP00000014615	ENSOMEP00000029118	ENSOMEP00000014615	COP9 signalosome subunit 6.	Cullin 4A; Belongs to the cullin family.	0.941
COPS6	ENSOMEP00000014790	ENSOMEP00000029118	ENSOMEP00000014790	COP9 signalosome subunit 6.	Uncharacterized protein.	0.684
COPS6	ENSOMEP00000020966	ENSOMEP00000029118	ENSOMEP00000020966	COP9 signalosome subunit 6.	Ribosomal protein S27a.	0.864
COPS6	ENSOMEP00000025354	ENSOMEP00000029118	ENSOMEP00000025354	COP9 signalosome subunit 6.	Polymerase (RNA) II (DNA directed) polypeptide F.	0.712
COPS6	ENSOMEP00000027875	ENSOMEP00000029118	ENSOMEP00000027875	COP9 signalosome subunit 6.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.701
COPS6	ENSOMEP00000027927	ENSOMEP00000029118	ENSOMEP00000027927	COP9 signalosome subunit 6.	Ubiquitin-like domain-containing protein.	0.808
COPS6	ENSOMEP00000035400	ENSOMEP00000029118	ENSOMEP00000035400	COP9 signalosome subunit 6.	Ubiquitin-like domain-containing protein.	0.833
COPS6	LOC112137766	ENSOMEP00000029118	ENSOMEP00000002266	COP9 signalosome subunit 6.	General transcription factor IIH subunit.	0.676
COPS6	LOC112159719	ENSOMEP00000029118	ENSOMEP00000012185	COP9 signalosome subunit 6.	Transcription elongation factor A (SII), 2.	0.441
COPS6	POLR2E	ENSOMEP00000029118	ENSOMEP00000001790	COP9 signalosome subunit 6.	RNA polymerase II subunit E.	0.755
COPS6	ccnh	ENSOMEP00000029118	ENSOMEP00000025213	COP9 signalosome subunit 6.	Cyclin H; Belongs to the cyclin family.	0.693
COPS6	cops2	ENSOMEP00000029118	ENSOMEP00000027127	COP9 signalosome subunit 6.	COP9 signalosome subunit 2.	0.999