27 items (Oryzias melastigma) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	prmt5	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (650 aa)
	ENSOMEP00000002606	Uncharacterized protein. (161 aa)
	ENSOMEP00000002833	Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
	l3mbtl3	L3MBTL histone methyl-lysine binding protein 1b. (865 aa)
	ENSOMEP00000004138	TAN domain-containing protein. (176 aa)
	ENSOMEP00000004154	Uncharacterized protein. (133 aa)
	JMY	Junction mediating and regulatory protein, p53 cofactor; Belongs to the globin family. (865 aa)
	LOC112146043	E1A binding protein p300 b. (2771 aa)
	LOC112153984	E1A binding protein p300 a. (2690 aa)
	ENSOMEP00000007809	Uncharacterized protein. (185 aa)
	ENSOMEP00000008371	ANK_REP_REGION domain-containing protein. (100 aa)
	LOC112156259	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (346 aa)
	ENSOMEP00000009469	Uncharacterized protein. (444 aa)
	ENSOMEP00000012540	Tetratricopeptide repeat domain 5. (444 aa)
	LOC112163195	Euchromatic histone-lysine N-methyltransferase 1b. (1403 aa)
	JMY-2	Junction mediating and regulatory protein, p53 cofactor. (839 aa)
	kmt5a	Lysine methyltransferase 5Aa. (332 aa)
	mdm2	MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (497 aa)
	LOC112148771	Lysine methyltransferase 5Ab. (325 aa)
	ENSOMEP00000023460	Uncharacterized protein. (85 aa)
	LOC112159033	L3MBTL histone methyl-lysine binding protein 1a. (845 aa)
	SETD9	SET domain containing 9. (263 aa)
	ehmt2	Euchromatic histone-lysine N-methyltransferase 2. (1181 aa)
	L3MBTL4	L3MBTL histone methyl-lysine binding protein 4. (386 aa)
	kxd1	KxDL motif containing 1. (195 aa)
	LOC112161085	SET and MYND domain containing 2a. (435 aa)
	ENSOMEP00000035400	Ubiquitin-like domain-containing protein. (137 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000002606	ENSOMEP00000004138	ENSOMEP00000002606	ENSOMEP00000004138	Uncharacterized protein.	TAN domain-containing protein.	0.962
ENSOMEP00000002606	ENSOMEP00000004154	ENSOMEP00000002606	ENSOMEP00000004154	Uncharacterized protein.	Uncharacterized protein.	0.933
ENSOMEP00000002606	ENSOMEP00000012540	ENSOMEP00000002606	ENSOMEP00000012540	Uncharacterized protein.	Tetratricopeptide repeat domain 5.	0.676
ENSOMEP00000002606	ENSOMEP00000035400	ENSOMEP00000002606	ENSOMEP00000035400	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.629
ENSOMEP00000002606	LOC112156259	ENSOMEP00000002606	ENSOMEP00000009309	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.961
ENSOMEP00000002606	mdm2	ENSOMEP00000002606	ENSOMEP00000021574	Uncharacterized protein.	MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family.	0.862
ENSOMEP00000002833	ENSOMEP00000008371	ENSOMEP00000002833	ENSOMEP00000008371	Ubiquitin A-52 residue ribosomal protein fusion product 1.	ANK_REP_REGION domain-containing protein.	0.808
ENSOMEP00000002833	ENSOMEP00000009469	ENSOMEP00000002833	ENSOMEP00000009469	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Uncharacterized protein.	0.643
ENSOMEP00000002833	ENSOMEP00000012540	ENSOMEP00000002833	ENSOMEP00000012540	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Tetratricopeptide repeat domain 5.	0.758
ENSOMEP00000002833	ENSOMEP00000035400	ENSOMEP00000002833	ENSOMEP00000035400	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Ubiquitin-like domain-containing protein.	0.999
ENSOMEP00000002833	LOC112146043	ENSOMEP00000002833	ENSOMEP00000004390	Ubiquitin A-52 residue ribosomal protein fusion product 1.	E1A binding protein p300 b.	0.599
ENSOMEP00000002833	LOC112148771	ENSOMEP00000002833	ENSOMEP00000022223	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Lysine methyltransferase 5Ab.	0.643
ENSOMEP00000002833	LOC112153984	ENSOMEP00000002833	ENSOMEP00000007732	Ubiquitin A-52 residue ribosomal protein fusion product 1.	E1A binding protein p300 a.	0.599
ENSOMEP00000002833	LOC112156259	ENSOMEP00000002833	ENSOMEP00000009309	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.659
ENSOMEP00000002833	LOC112161085	ENSOMEP00000002833	ENSOMEP00000027608	Ubiquitin A-52 residue ribosomal protein fusion product 1.	SET and MYND domain containing 2a.	0.643
ENSOMEP00000002833	LOC112163195	ENSOMEP00000002833	ENSOMEP00000014939	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Euchromatic histone-lysine N-methyltransferase 1b.	0.808
ENSOMEP00000002833	ehmt2	ENSOMEP00000002833	ENSOMEP00000026680	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Euchromatic histone-lysine N-methyltransferase 2.	0.808
ENSOMEP00000002833	kmt5a	ENSOMEP00000002833	ENSOMEP00000017651	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Lysine methyltransferase 5Aa.	0.643
ENSOMEP00000002833	kxd1	ENSOMEP00000002833	ENSOMEP00000027436	Ubiquitin A-52 residue ribosomal protein fusion product 1.	KxDL motif containing 1.	0.779
ENSOMEP00000002833	mdm2	ENSOMEP00000002833	ENSOMEP00000021574	Ubiquitin A-52 residue ribosomal protein fusion product 1.	MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family.	0.963