STRINGSTRING
ENSOMEP00000021057 ENSOMEP00000021057 tm7sf3 tm7sf3 fam89a fam89a ENSOMEP00000021566 ENSOMEP00000021566 cdt1 cdt1 mcm2 mcm2 ENSOMEP00000024214 ENSOMEP00000024214 psmc4 psmc4 psmb2 psmb2 ENSOMEP00000025203 ENSOMEP00000025203 psma4 psma4 kpna1 kpna1 ENSOMEP00000026302 ENSOMEP00000026302 ENSOMEP00000026313 ENSOMEP00000026313 psmd12 psmd12 ENSOMEP00000026794 ENSOMEP00000026794 ENSOMEP00000026824 ENSOMEP00000026824 ENSOMEP00000026888 ENSOMEP00000026888 mcm5 mcm5 LOC112147217 LOC112147217 psmd7 psmd7 orc3 orc3 kxd1 kxd1 ENSOMEP00000027698 ENSOMEP00000027698 psme2 psme2 ENSOMEP00000000357 ENSOMEP00000000357 psmd8 psmd8 mcm8 mcm8 psmd9 psmd9 ube2c ube2c ENSOMEP00000001528 ENSOMEP00000001528 anapc15 anapc15 psma1 psma1 LOC112136564 LOC112136564 ENSOMEP00000002833 ENSOMEP00000002833 psmd11 psmd11 psme3 psme3 LOC112144185 LOC112144185 H2AZ1 H2AZ1 LOC112140822 LOC112140822 psma5 psma5 psmc3 psmc3 psmb1 psmb1 PSMD4 PSMD4 ENSOMEP00000005576 ENSOMEP00000005576 kpna6 kpna6 anapc11 anapc11 bicral bicral LOC112156864 LOC112156864 ENSOMEP00000035400 ENSOMEP00000035400 cdc23 cdc23 ENSOMEP00000034970 ENSOMEP00000034970 ENSOMEP00000034008 ENSOMEP00000034008 LOC112140154 LOC112140154 LOC112137884 LOC112137884 psma3 psma3 psmd2 psmd2 psmb3 psmb3 ENSOMEP00000032934 ENSOMEP00000032934 ENSOMEP00000032897 ENSOMEP00000032897 ENSOMEP00000032839 ENSOMEP00000032839 LOC112150025 LOC112150025 LOC112140822-3 LOC112140822-3 LOC112137399 LOC112137399 ENSOMEP00000027783 ENSOMEP00000027783 ENSOMEP00000027927 ENSOMEP00000027927 ENSOMEP00000028219 ENSOMEP00000028219 ENSOMEP00000028753 ENSOMEP00000028753 psmc2 psmc2 psmd10 psmd10 cdc16 cdc16 anapc2 anapc2 ENSOMEP00000031513 ENSOMEP00000031513 psme1 psme1 ENSOMEP00000031710 ENSOMEP00000031710 anapc5 anapc5 LOC112137408 LOC112137408 LOC112137393 LOC112137393 psmb6 psmb6 ENSOMEP00000006622 ENSOMEP00000006622 ENSOMEP00000006627 ENSOMEP00000006627 LOC112138059 LOC112138059 ENSOMEP00000006978 ENSOMEP00000006978 ENSOMEP00000007070 ENSOMEP00000007070 ENSOMEP00000007665 ENSOMEP00000007665 psmd6 psmd6 H3-3B H3-3B ENSOMEP00000009110 ENSOMEP00000009110 ENSOMEP00000009159 ENSOMEP00000009159 ENSOMEP00000009187 ENSOMEP00000009187 ENSOMEP00000009479 ENSOMEP00000009479 ube2s ube2s mcm6 mcm6 orc2 orc2 psmd13 psmd13 psmc6 psmc6 MCM9 MCM9 gmnn gmnn mcm7 mcm7 psmf1 psmf1 ENSOMEP00000011806 ENSOMEP00000011806 LOC112147624 LOC112147624 LOC112149581 LOC112149581 psmc1 psmc1 ENSOMEP00000012830 ENSOMEP00000012830 ENSOMEP00000013031 ENSOMEP00000013031 psmd14 psmd14 ENSOMEP00000013312 ENSOMEP00000013312 mcm3 mcm3 cdc27 cdc27 LOC112140822-2 LOC112140822-2 orc1 orc1 ENSOMEP00000015130 ENSOMEP00000015130 LOC112136178 LOC112136178 psma2 psma2 psmb7 psmb7 ENSOMEP00000016643 ENSOMEP00000016643 ENSOMEP00000016821 ENSOMEP00000016821 ENSOMEP00000016897 ENSOMEP00000016897 LOC112140153 LOC112140153 LOC112140152 LOC112140152 orc4 orc4 cdc26 cdc26 FZR1 FZR1 kpnb1 kpnb1 ENSOMEP00000019316 ENSOMEP00000019316 psmd1 psmd1 psmc5 psmc5 ENSOMEP00000020966 ENSOMEP00000020966
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSOMEP00000021057Histone H2A; Belongs to the histone H2A family. (132 aa)
tm7sf3Transmembrane 7 superfamily member 3. (563 aa)
fam89aFamily with sequence similarity 89 member A. (175 aa)
ENSOMEP00000021566Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (217 aa)
cdt1Chromatin licensing and DNA replication factor 1. (580 aa)
mcm2DNA helicase; Belongs to the MCM family. (887 aa)
ENSOMEP00000024214Origin recognition complex, subunit 5. (465 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
psmb2Proteasome subunit beta. (199 aa)
ENSOMEP00000025203Proteasome 26S subunit, non-ATPase 4b. (367 aa)
psma4Proteasome subunit alpha type. (261 aa)
kpna1Importin subunit alpha; Belongs to the importin alpha family. (538 aa)
ENSOMEP00000026302Si:dkey-261m9.6; Belongs to the histone H2B family. (111 aa)
ENSOMEP00000026313Histone H2A; Belongs to the histone H2A family. (144 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSOMEP00000026794Histone H2A; Belongs to the histone H2A family. (143 aa)
ENSOMEP00000026824Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (98 aa)
ENSOMEP00000026888Proteasome 26S subunit, non-ATPase 5. (475 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
LOC112147217Fizzy/cell division cycle 20 related 1b. (487 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (324 aa)
orc3Origin recognition complex, subunit 3. (716 aa)
kxd1KxDL motif containing 1. (195 aa)
ENSOMEP00000027698Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
psme2Proteasome activator subunit 2. (243 aa)
ENSOMEP00000000357BRD4 interacting chromatin remodeling complex associated protein. (1683 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (265 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (868 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (223 aa)
ENSOMEP00000001528Histone H2A; Belongs to the histone H2A family. (125 aa)
anapc15Anaphase promoting complex subunit 15. (122 aa)
psma1Proteasome subunit alpha type. (267 aa)
LOC112136564UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
ENSOMEP00000002833Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
psmd11Proteasome 26S subunit, non-ATPase 11b. (422 aa)
psme3Proteasome activator subunit 3. (256 aa)
LOC112144185Proteasome subunit beta. (278 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC112140822Histone H3; Belongs to the histone H3 family. (136 aa)
psma5Proteasome subunit alpha type. (241 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
psmb1Proteasome subunit beta. (237 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4a. (372 aa)
ENSOMEP00000005576DNA helicase; Belongs to the MCM family. (894 aa)
kpna6Importin subunit alpha; Belongs to the importin alpha family. (538 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
bicralBRD4 interacting chromatin remodeling complex associated protein like. (773 aa)
LOC112156864Histone H2A; Belongs to the histone H2A family. (128 aa)
ENSOMEP00000035400Ubiquitin-like domain-containing protein. (137 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (642 aa)
ENSOMEP00000034970Anaphase promoting complex subunit 7. (565 aa)
ENSOMEP00000034008Proteasome subunit beta 9a. (114 aa)
LOC112140154Proteasome subunit beta 12. (217 aa)
LOC112137884Ubiquitin-conjugating enzyme E2E 1; Belongs to the ubiquitin-conjugating enzyme family. (208 aa)
psma3Proteasome subunit alpha type. (255 aa)
psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)
psmb3Proteasome subunit beta. (206 aa)
ENSOMEP00000032934Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa)
ENSOMEP00000032897Histone H2B; Belongs to the histone H2B family. (113 aa)
ENSOMEP00000032839Histone H2B; Belongs to the histone H2B family. (115 aa)
LOC112150025Proteasome subunit alpha type. (246 aa)
LOC112140822-3Histone H3.3-like. (136 aa)
LOC112137399Proteasome subunit beta. (272 aa)
ENSOMEP00000027783Proteasome subunit beta; Belongs to the peptidase T1B family. (225 aa)
ENSOMEP00000027927Ubiquitin-like domain-containing protein. (77 aa)
ENSOMEP00000028219Proteasome endopeptidase complex. (228 aa)
ENSOMEP00000028753Anaphase promoting complex subunit 16. (135 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (618 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (806 aa)
ENSOMEP00000031513ANAPC4_WD40 domain-containing protein. (206 aa)
psme1Proteasome activator subunit 1. (261 aa)
ENSOMEP00000031710Histone H2B; Belongs to the histone H2B family. (115 aa)
anapc5Anaphase promoting complex subunit 5. (773 aa)
LOC112137408Proteasome subunit beta 12. (217 aa)
LOC112137393Proteasome subunit beta. (275 aa)
psmb6Proteasome subunit beta. (232 aa)
ENSOMEP00000006622Histone H2B; Belongs to the histone H2B family. (170 aa)
ENSOMEP00000006627Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (149 aa)
LOC112138059Histone H2B 1/2. (124 aa)
ENSOMEP00000006978Histone H2A; Belongs to the histone H2A family. (158 aa)
ENSOMEP00000007070VWFA domain-containing protein. (229 aa)
ENSOMEP00000007665Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
H3-3BHistone H3; Belongs to the histone H3 family. (141 aa)
ENSOMEP00000009110H2A histone family, member Va; Belongs to the histone H2A family. (356 aa)
ENSOMEP00000009159Histone H2B; Belongs to the histone H2B family. (110 aa)
ENSOMEP00000009187Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa)
ENSOMEP00000009479Uncharacterized protein; Belongs to the histone H2A family. (245 aa)
ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (232 aa)
mcm6DNA helicase; Belongs to the MCM family. (827 aa)
orc2Origin recognition complex, subunit 2. (564 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (378 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1100 aa)
gmnnGeminin DNA replication inhibitor. (227 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
psmf1Proteasome inhibitor subunit 1. (313 aa)
ENSOMEP00000011806Anaphase promoting complex subunit 1. (1855 aa)
LOC112147624Proteasome subunit beta. (271 aa)
LOC112149581Histone H2A; Belongs to the histone H2A family. (138 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
ENSOMEP00000012830Proteasome subunit alpha type. (292 aa)
ENSOMEP00000013031Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (452 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
ENSOMEP00000013312Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (145 aa)
mcm3DNA helicase; Belongs to the MCM family. (817 aa)
cdc27Cell division cycle 27. (802 aa)
LOC112140822-2Histone H3.3-like. (136 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (907 aa)
ENSOMEP00000015130Histone H2B; Belongs to the histone H2B family. (114 aa)
LOC112136178Proteasome subunit beta. (216 aa)
psma2Proteasome subunit alpha type. (234 aa)
psmb7Proteasome subunit beta. (307 aa)
ENSOMEP00000016643Histone H3; Belongs to the histone H3 family. (143 aa)
ENSOMEP00000016821Histone H2B; Belongs to the histone H2B family. (130 aa)
ENSOMEP00000016897Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (101 aa)
LOC112140153Proteasome subunit beta. (275 aa)
LOC112140152Proteasome subunit beta. (275 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (433 aa)
cdc26Cell division cycle 26 homolog. (93 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (498 aa)
kpnb1Karyopherin (importin) beta 1. (897 aa)
ENSOMEP00000019316Proteasome 26S subunit, non-ATPase 3. (567 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
ENSOMEP00000020966Ribosomal protein S27a. (183 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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