STRINGSTRING
LOC112140154 LOC112140154 ENSOMEP00000034008 ENSOMEP00000034008 cdk2 cdk2 ENSOMEP00000035400 ENSOMEP00000035400 ENSOMEP00000036314 ENSOMEP00000036314 ENSOMEP00000035622 ENSOMEP00000035622 psme2 psme2 psmd8 psmd8 ENSOMEP00000000533 ENSOMEP00000000533 psmd9 psmd9 ccna2 ccna2 psma1 psma1 ENSOMEP00000002606 ENSOMEP00000002606 ENSOMEP00000002833 ENSOMEP00000002833 psmd11 psmd11 psma8 psma8 psme3 psme3 ZNF385C ZNF385C LOC112144185 LOC112144185 ENSOMEP00000004138 ENSOMEP00000004138 ENSOMEP00000004154 ENSOMEP00000004154 psma5 psma5 psmc3 psmc3 psmb1 psmb1 cdkn1c cdkn1c PSMD4 PSMD4 psmb6 psmb6 cdkn1b cdkn1b ENSOMEP00000007070 ENSOMEP00000007070 LOC112145655 LOC112145655 psmd6 psmd6 ENSOMEP00000008693 ENSOMEP00000008693 LOC112156259 LOC112156259 psmd13 psmd13 psmc6 psmc6 ccna1 ccna1 psmf1 psmf1 LOC112147624 LOC112147624 psmc1 psmc1 ENSOMEP00000012830 ENSOMEP00000012830 LOC112158072 LOC112158072 ENSOMEP00000012955 ENSOMEP00000012955 psmd14 psmd14 znf385b znf385b LOC112136178 LOC112136178 psma2 psma2 ENSOMEP00000015819 ENSOMEP00000015819 LOC112159370 LOC112159370 psmb7 psmb7 mdm4 mdm4 LOC112140153 LOC112140153 ENSOMEP00000019316 ENSOMEP00000019316 ccne1 ccne1 ccne2 ccne2 psmd1 psmd1 psmc5 psmc5 ENSOMEP00000020966 ENSOMEP00000020966 mdm2 mdm2 ENSOMEP00000023460 ENSOMEP00000023460 ENSOMEP00000024089 ENSOMEP00000024089 psmc4 psmc4 LOC112150731 LOC112150731 psmb2 psmb2 ENSOMEP00000025203 ENSOMEP00000025203 psma4 psma4 psmd12 psmd12 ENSOMEP00000026888 ENSOMEP00000026888 psmd7 psmd7 ENSOMEP00000027431 ENSOMEP00000027431 kxd1 kxd1 ENSOMEP00000027783 ENSOMEP00000027783 ENSOMEP00000027927 ENSOMEP00000027927 ENSOMEP00000028219 ENSOMEP00000028219 ENSOMEP00000029329 ENSOMEP00000029329 psmc2 psmc2 LOC112147746 LOC112147746 psmd10 psmd10 LOC112144588 LOC112144588 cop1 cop1 psme1 psme1 LOC112137408 LOC112137408 LOC112137399 LOC112137399 LOC112150025 LOC112150025 psmb3 psmb3 psma3 psma3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC112140154Proteasome subunit beta 12. (217 aa)
ENSOMEP00000034008Proteasome subunit beta 9a. (114 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
ENSOMEP00000035400Ubiquitin-like domain-containing protein. (137 aa)
ENSOMEP00000036314Tudor domain-containing protein. (147 aa)
ENSOMEP00000035622Zinc finger protein 385C. (480 aa)
psme2Proteasome activator subunit 2. (243 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (265 aa)
ENSOMEP00000000533Proteasome activator subunit 4a. (1817 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (431 aa)
psma1Proteasome subunit alpha type. (267 aa)
ENSOMEP00000002606Uncharacterized protein. (161 aa)
ENSOMEP00000002833Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
psmd11Proteasome 26S subunit, non-ATPase 11b. (422 aa)
psma8Proteasome subunit alpha type. (251 aa)
psme3Proteasome activator subunit 3. (256 aa)
ZNF385CZinc finger protein 385C. (541 aa)
LOC112144185Proteasome subunit beta. (278 aa)
ENSOMEP00000004138TAN domain-containing protein. (176 aa)
ENSOMEP00000004154Uncharacterized protein. (133 aa)
psma5Proteasome subunit alpha type. (241 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
psmb1Proteasome subunit beta. (237 aa)
cdkn1cUncharacterized protein. (207 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4a. (372 aa)
psmb6Proteasome subunit beta. (232 aa)
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (180 aa)
ENSOMEP00000007070VWFA domain-containing protein. (229 aa)
LOC112145655Uncharacterized protein. (417 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
ENSOMEP00000008693DUF3437 domain-containing protein. (181 aa)
LOC112156259Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (346 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (378 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (457 aa)
psmf1Proteasome inhibitor subunit 1. (313 aa)
LOC112147624Proteasome subunit beta. (271 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
ENSOMEP00000012830Proteasome subunit alpha type. (292 aa)
LOC112158072Cyclin-dependent kinase inhibitor 1D. (177 aa)
ENSOMEP00000012955Uncharacterized protein. (171 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
znf385bZinc finger protein 385B. (573 aa)
LOC112136178Proteasome subunit beta. (216 aa)
psma2Proteasome subunit alpha type. (234 aa)
ENSOMEP00000015819Protein kinase domain-containing protein. (358 aa)
LOC112159370Zinc finger protein 385A. (474 aa)
psmb7Proteasome subunit beta. (307 aa)
mdm4MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (491 aa)
LOC112140153Proteasome subunit beta. (275 aa)
ENSOMEP00000019316Proteasome 26S subunit, non-ATPase 3. (567 aa)
ccne1Cyclin E1; Belongs to the cyclin family. (423 aa)
ccne2Cyclin E2; Belongs to the cyclin family. (395 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
ENSOMEP00000020966Ribosomal protein S27a. (183 aa)
mdm2MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (497 aa)
ENSOMEP00000023460Uncharacterized protein. (85 aa)
ENSOMEP00000024089Uncharacterized protein. (154 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
LOC112150731Proteasome subunit beta11b. (359 aa)
psmb2Proteasome subunit beta. (199 aa)
ENSOMEP00000025203Proteasome 26S subunit, non-ATPase 4b. (367 aa)
psma4Proteasome subunit alpha type. (261 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSOMEP00000026888Proteasome 26S subunit, non-ATPase 5. (475 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (324 aa)
ENSOMEP00000027431BLM10_mid domain-containing protein. (548 aa)
kxd1KxDL motif containing 1. (195 aa)
ENSOMEP00000027783Proteasome subunit beta; Belongs to the peptidase T1B family. (225 aa)
ENSOMEP00000027927Ubiquitin-like domain-containing protein. (77 aa)
ENSOMEP00000028219Proteasome endopeptidase complex. (228 aa)
ENSOMEP00000029329Uncharacterized protein. (156 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
LOC112147746Proteasome subunit beta. (298 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
LOC112144588Cyclin-dependent kinase inhibitor 1A. (164 aa)
cop1COP1 E3 ubiquitin ligase. (705 aa)
psme1Proteasome activator subunit 1. (261 aa)
LOC112137408Proteasome subunit beta 12. (217 aa)
LOC112137399Proteasome subunit beta. (272 aa)
LOC112150025Proteasome subunit alpha type. (246 aa)
psmb3Proteasome subunit beta. (206 aa)
psma3Proteasome subunit alpha type. (255 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.