STRINGSTRING
pole2 pole2 rfc4 rfc4 ENSOMEP00000014615 ENSOMEP00000014615 pold1 pold1 pclaf pclaf ENSOMEP00000016164 ENSOMEP00000016164 usp43 usp43 ENSOMEP00000016961 ENSOMEP00000016961 LOC112141685 LOC112141685 rchy1 rchy1 nploc4 nploc4 ENSOMEP00000019716 ENSOMEP00000019716 ENSOMEP00000019912 ENSOMEP00000019912 LOC112156170 LOC112156170 ENSOMEP00000020384 ENSOMEP00000020384 ENSOMEP00000020966 ENSOMEP00000020966 LOC112156400 LOC112156400 LOC112162777 LOC112162777 ENSOMEP00000021420 ENSOMEP00000021420 ENSOMEP00000021421 ENSOMEP00000021421 usp10 usp10 SPATA5 SPATA5 ENSOMEP00000023283 ENSOMEP00000023283 ENSOMEP00000023773 ENSOMEP00000023773 rbx1 rbx1 ENSOMEP00000004644 ENSOMEP00000004644 polk polk rpa1 rpa1 ENSOMEP00000003573 ENSOMEP00000003573 vcp vcp ENSOMEP00000002833 ENSOMEP00000002833 LOC112160043 LOC112160043 pole3 pole3 ENSOMEP00000002326 ENSOMEP00000002326 pole pole pold3 pold3 rcbtb2 rcbtb2 ENSOMEP00000000017 ENSOMEP00000000017 rfc2 rfc2 cul4b cul4b ENSOMEP00000030878 ENSOMEP00000030878 ufd1 ufd1 LOC112153972 LOC112153972 ENSOMEP00000032610 ENSOMEP00000032610 rpa2 rpa2 pcna pcna ENSOMEP00000032968 ENSOMEP00000032968 ENSOMEP00000033193 ENSOMEP00000033193 LOC112156637 LOC112156637 LOC112157526 LOC112157526 LOC112156169 LOC112156169 ENSOMEP00000035400 ENSOMEP00000035400 sprtn sprtn dtl dtl rpa3 rpa3 ENSOMEP00000026498 ENSOMEP00000026498 pole4 pole4 kxd1 kxd1 ENSOMEP00000027572 ENSOMEP00000027572 ENSOMEP00000027927 ENSOMEP00000027927 LOC112142882 LOC112142882 poli poli rev3l rev3l ENSOMEP00000028590 ENSOMEP00000028590 wdr48 wdr48 ENSOMEP00000028815 ENSOMEP00000028815 ENSOMEP00000005155 ENSOMEP00000005155 meiob meiob mad2l2 mad2l2 LOC112159947 LOC112159947 ENSOMEP00000007258 ENSOMEP00000007258 ENSOMEP00000028916 ENSOMEP00000028916 LOC112137186 LOC112137186 LOC112146819 LOC112146819 spata5l1 spata5l1 LOC112150438 LOC112150438 ENSOMEP00000008475 ENSOMEP00000008475 ENSOMEP00000008529 ENSOMEP00000008529 RPA1 RPA1 rev1 rev1 ENSOMEP00000010830 ENSOMEP00000010830 RCBTB1 RCBTB1 ENSOMEP00000011219 ENSOMEP00000011219 LOC112148474 LOC112148474 rad18 rad18 LOC112146405 LOC112146405
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
rfc4Replication factor C (activator 1) 4. (355 aa)
ENSOMEP00000014615Cullin 4A; Belongs to the cullin family. (760 aa)
pold1DNA polymerase. (1105 aa)
pclafPCNA clamp associated factor. (117 aa)
ENSOMEP00000016164Uncharacterized protein. (218 aa)
usp43Ubiquitin specific peptidase 43a; Belongs to the peptidase C19 family. (1208 aa)
ENSOMEP00000016961B30.2/SPRY domain-containing protein. (243 aa)
LOC112141685Uncharacterized protein. (595 aa)
rchy1Ring finger and CHY zinc finger domain containing 1. (261 aa)
nploc4NPL4 homolog, ubiquitin recognition factor. (622 aa)
ENSOMEP00000019716Si:dkey-46i9.6. (555 aa)
ENSOMEP00000019912B30.2/SPRY domain-containing protein. (258 aa)
LOC112156170Uncharacterized protein. (562 aa)
ENSOMEP00000020384Uncharacterized protein. (391 aa)
ENSOMEP00000020966Ribosomal protein S27a. (183 aa)
LOC112156400Uncharacterized protein. (489 aa)
LOC112162777UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
ENSOMEP00000021420CHY-type domain-containing protein. (211 aa)
ENSOMEP00000021421B30.2/SPRY domain-containing protein. (270 aa)
usp10Ubiquitin carboxyl-terminal hydrolase. (899 aa)
SPATA5Spermatogenesis associated 5. (792 aa)
ENSOMEP00000023283RING-type domain-containing protein. (113 aa)
ENSOMEP00000023773B box-type domain-containing protein. (201 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
ENSOMEP00000004644Polymerase (DNA directed), eta. (302 aa)
polkPolymerase (DNA directed) kappa. (847 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (598 aa)
ENSOMEP00000003573Uncharacterized protein. (545 aa)
vcpValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
ENSOMEP00000002833Ubiquitin A-52 residue ribosomal protein fusion product 1. (129 aa)
LOC112160043Tripartite motif containing 25, like. (804 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (147 aa)
ENSOMEP00000002326Uncharacterized protein. (526 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2291 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (438 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (547 aa)
ENSOMEP00000000017Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1273 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
cul4bCullin 4B; Belongs to the cullin family. (864 aa)
ENSOMEP00000030878B30.2/SPRY domain-containing protein. (244 aa)
ufd1Ubiquitin recognition factor in ER associated degradation 1. (310 aa)
LOC112153972USP domain-containing protein; Belongs to the peptidase C19 family. (1283 aa)
ENSOMEP00000032610B30.2/SPRY domain-containing protein. (221 aa)
rpa2Replication protein A2. (270 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
ENSOMEP00000032968Uncharacterized protein. (324 aa)
ENSOMEP00000033193B30.2/SPRY domain-containing protein. (288 aa)
LOC112156637Uncharacterized protein. (538 aa)
LOC112157526Bloodthirsty-related gene family, member 1. (555 aa)
LOC112156169Bloodthirsty-related gene family, member 12. (618 aa)
ENSOMEP00000035400Ubiquitin-like domain-containing protein. (137 aa)
sprtnSprT-like N-terminal domain. (539 aa)
dtlDenticleless E3 ubiquitin protein ligase homolog (Drosophila). (646 aa)
rpa3Replication protein A3. (122 aa)
ENSOMEP00000026498Uncharacterized protein. (491 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (148 aa)
kxd1KxDL motif containing 1. (195 aa)
ENSOMEP00000027572FinTRIM family, member 67. (454 aa)
ENSOMEP00000027927Ubiquitin-like domain-containing protein. (77 aa)
LOC112142882FinTRIM family, member 82. (574 aa)
poliPolymerase (DNA directed) iota. (714 aa)
rev3lREV3 like, DNA directed polymerase zeta catalytic subunit. (2959 aa)
ENSOMEP00000028590Uncharacterized protein. (106 aa)
wdr48WD repeat domain 48b. (677 aa)
ENSOMEP00000028815Replication factor C (activator 1) 3. (279 aa)
ENSOMEP00000005155Damage-specific DNA binding protein 1. (1105 aa)
meiobMethionine sulfoxide reductase B1b. (461 aa)
mad2l2Mitotic arrest deficient 2 like 2. (210 aa)
LOC112159947Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (573 aa)
ENSOMEP00000007258Ubiquitin carboxyl-terminal hydrolase. (784 aa)
ENSOMEP00000028916Replication factor C subunit 1. (1042 aa)
LOC112137186Uncharacterized protein. (568 aa)
LOC112146819Ubiquitin specific peptidase 43b; Belongs to the peptidase C19 family. (1209 aa)
spata5l1Spermatogenesis associated 5-like 1. (750 aa)
LOC112150438SCY domain-containing protein. (126 aa)
ENSOMEP00000008475Uncharacterized protein. (454 aa)
ENSOMEP00000008529Uncharacterized protein. (383 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (649 aa)
rev1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1347 aa)
ENSOMEP00000010830Replication factor C (activator 1) 5. (326 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (527 aa)
ENSOMEP00000011219Uncharacterized protein. (96 aa)
LOC112148474Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
rad18RAD18 E3 ubiquitin protein ligase. (487 aa)
LOC112146405ATPase family AAA domain containing 5a. (1739 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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