(8 nodes) Assembly of active LPL and LIPC lipase complexes network (Oryzias melastigma)

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Your Input:
	lmf1	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (572 aa)
	LOC112150654	PLAT domain-containing protein. (510 aa)
	ENSOMEP00000005720	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (730 aa)
	angptl3	Angiopoietin-like 3. (472 aa)
	lpl	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (514 aa)
	angptl4	Angiopoietin-like 4. (464 aa)
	furin	Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (835 aa)
	ENSOMEP00000020859	Uncharacterized protein. (245 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000005720	LOC112150654	ENSOMEP00000005720	ENSOMEP00000007979	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	PLAT domain-containing protein.	0.420
ENSOMEP00000005720	lmf1	ENSOMEP00000005720	ENSOMEP00000009033	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	0.671
ENSOMEP00000005720	lpl	ENSOMEP00000005720	ENSOMEP00000007951	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.420
LOC112150654	ENSOMEP00000005720	ENSOMEP00000007979	ENSOMEP00000005720	PLAT domain-containing protein.	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	0.420
LOC112150654	angptl3	ENSOMEP00000007979	ENSOMEP00000007142	PLAT domain-containing protein.	Angiopoietin-like 3.	0.760
LOC112150654	angptl4	ENSOMEP00000007979	ENSOMEP00000031981	PLAT domain-containing protein.	Angiopoietin-like 4.	0.722
LOC112150654	lpl	ENSOMEP00000007979	ENSOMEP00000007951	PLAT domain-containing protein.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.893
angptl3	LOC112150654	ENSOMEP00000007142	ENSOMEP00000007979	Angiopoietin-like 3.	PLAT domain-containing protein.	0.760
angptl3	angptl4	ENSOMEP00000007142	ENSOMEP00000031981	Angiopoietin-like 3.	Angiopoietin-like 4.	0.782
angptl3	lmf1	ENSOMEP00000007142	ENSOMEP00000009033	Angiopoietin-like 3.	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	0.439
angptl3	lpl	ENSOMEP00000007142	ENSOMEP00000007951	Angiopoietin-like 3.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.760
angptl4	LOC112150654	ENSOMEP00000031981	ENSOMEP00000007979	Angiopoietin-like 4.	PLAT domain-containing protein.	0.722
angptl4	angptl3	ENSOMEP00000031981	ENSOMEP00000007142	Angiopoietin-like 4.	Angiopoietin-like 3.	0.782
angptl4	lmf1	ENSOMEP00000031981	ENSOMEP00000009033	Angiopoietin-like 4.	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	0.401
angptl4	lpl	ENSOMEP00000031981	ENSOMEP00000007951	Angiopoietin-like 4.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.722
lmf1	ENSOMEP00000005720	ENSOMEP00000009033	ENSOMEP00000005720	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	0.671
lmf1	angptl3	ENSOMEP00000009033	ENSOMEP00000007142	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	Angiopoietin-like 3.	0.439
lmf1	angptl4	ENSOMEP00000009033	ENSOMEP00000031981	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	Angiopoietin-like 4.	0.401
lpl	ENSOMEP00000005720	ENSOMEP00000007951	ENSOMEP00000005720	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	0.420
lpl	LOC112150654	ENSOMEP00000007951	ENSOMEP00000007979	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	PLAT domain-containing protein.	0.893