STRINGSTRING
ENSOMEP00000028531 ENSOMEP00000028531 ENSOMEP00000028106 ENSOMEP00000028106 hmox1 hmox1 DDX5 DDX5 jun jun casp9 casp9 ehmt2 ehmt2 sod2 sod2 LOC112144782 LOC112144782 dusp8 dusp8 ACLY ACLY ostf1 ostf1 CASP3 CASP3 GPX4 GPX4 ENSOMEP00000017789 ENSOMEP00000017789 col1a2 col1a2 ENSOMEP00000014890 ENSOMEP00000014890 phkg1 phkg1 srebf1 srebf1 insr insr dgat2 dgat2 LOC112154371 LOC112154371 LOC112145294 LOC112145294 GHITM GHITM ENSOMEP00000009320 ENSOMEP00000009320 LOC112136473 LOC112136473 PER2 PER2 hif1a hif1a ENSOMEP00000005774 ENSOMEP00000005774 mknk1 mknk1 ireb2 ireb2 atf2 atf2 epo epo ENSOMEP00000001720 ENSOMEP00000001720 LOC112144901 LOC112144901 dao dao COX5A COX5A ACLY-2 ACLY-2 ENSOMEP00000000883 ENSOMEP00000000883 BCO2 BCO2 oxct1 oxct1 igfals igfals angptl4 angptl4 myb myb gpx8 gpx8 gpx7 gpx7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSOMEP00000028531Glutathione peroxidase; Belongs to the glutathione peroxidase family. (128 aa)
ENSOMEP00000028106Glutathione peroxidase; Belongs to the glutathione peroxidase family. (184 aa)
hmox1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (268 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (630 aa)
junBZIP domain-containing protein; Belongs to the bZIP family. (293 aa)
casp9Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (434 aa)
ehmt2Euchromatic histone-lysine N-methyltransferase 2. (1181 aa)
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (225 aa)
LOC112144782Cytochrome b561 family, member D2. (224 aa)
dusp8Dual specificity phosphatase 8a. (657 aa)
ACLYATP citrate lyase. (428 aa)
ostf1Osteoclast stimulating factor 1. (214 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (290 aa)
GPX4Glutathione peroxidase; Belongs to the glutathione peroxidase family. (112 aa)
ENSOMEP00000017789Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b. (2317 aa)
col1a2Collagen, type I, alpha 2. (1356 aa)
ENSOMEP00000014890Serine/threonine-protein kinase TOR. (1003 aa)
phkg1Phosphorylase kinase, gamma 1a (muscle); Belongs to the protein kinase superfamily. (394 aa)
srebf1Sterol regulatory element binding transcription factor 1. (1179 aa)
insrTyrosine-protein kinase receptor. (1359 aa)
dgat2Diacylglycerol O-acyltransferase 2. (391 aa)
LOC112154371Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (333 aa)
LOC112145294Solute carrier family 2 member 1b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (491 aa)
GHITMGrowth hormone inducible transmembrane protein; Belongs to the BI1 family. (348 aa)
ENSOMEP00000009320Glutathione peroxidase; Belongs to the glutathione peroxidase family. (152 aa)
LOC112136473Calcium binding protein 39. (341 aa)
PER2Period circadian regulator 2. (1460 aa)
hif1aHypoxia inducible factor 1 subunit alpha a. (748 aa)
ENSOMEP00000005774Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (474 aa)
mknk1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (457 aa)
ireb2Iron-responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (986 aa)
atf2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa)
epoErythropoietin; Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Belongs to the EPO/TPO family. (185 aa)
ENSOMEP00000001720Glutathione peroxidase; Belongs to the glutathione peroxidase family. (183 aa)
LOC112144901Glutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
daoD-amino-acid oxidase, tandem duplicate 2. (343 aa)
COX5ACytochrome c oxidase subunit 5Ab. (141 aa)
ACLY-2ATP citrate lyase. (438 aa)
ENSOMEP00000000883Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (294 aa)
BCO2Beta-carotene oxygenase 2b. (570 aa)
oxct1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (527 aa)
igfalsInsulin-like growth factor binding protein, acid labile subunit. (577 aa)
angptl4Angiopoietin-like 4. (464 aa)
mybV-myb avian myeloblastosis viral oncogene homolog. (590 aa)
gpx8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa)
gpx7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (185 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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