STRINGSTRING
ENSOMEP00000012775 ENSOMEP00000012775 elovl5 elovl5 ENSOMEP00000001803 ENSOMEP00000001803 LOC112154472 LOC112154472 LOC112151954 LOC112151954 LOC112160728 LOC112160728 LOC112161173 LOC112161173 acot7 acot7 LOC112137624 LOC112137624 depdc4 depdc4 LOC112150829 LOC112150829 LOC112137470 LOC112137470 ENSOMEP00000006496 ENSOMEP00000006496 bsn bsn abhd13 abhd13 acox1 acox1 ENSOMEP00000010365 ENSOMEP00000010365 LOC112145803 LOC112145803 LOC112154371 LOC112154371 LOC112152671 LOC112152671 ENSOMEP00000014038 ENSOMEP00000014038 LOC112143893 LOC112143893 LOC112151473 LOC112151473 ENSOMEP00000017038 ENSOMEP00000017038 LOC112151777 LOC112151777 LOC112147450 LOC112147450 hsd17b4 hsd17b4 znf277 znf277 ENSOMEP00000020703 ENSOMEP00000020703 pggt1b pggt1b hsdl1 hsdl1 LOC112158782 LOC112158782 LOC112162957 LOC112162957 ENSOMEP00000021624 ENSOMEP00000021624 HACD3 HACD3 ENSOMEP00000022470 ENSOMEP00000022470 hacd1 hacd1 hacd4 hacd4 LOC112161383 LOC112161383 ENSOMEP00000024663 ENSOMEP00000024663 ENSOMEP00000024728 ENSOMEP00000024728 LOC112136963 LOC112136963 tcp11l2 tcp11l2 LOC112150713 LOC112150713 ENSOMEP00000025401 ENSOMEP00000025401 elovl6 elovl6 abhd17b abhd17b ENSOMEP00000027260 ENSOMEP00000027260 scp2 scp2 tcp11l1 tcp11l1 LOC112138814 LOC112138814 hacd2 hacd2 ENSOMEP00000032900 ENSOMEP00000032900 ENSOMEP00000033023 ENSOMEP00000033023 acox3 acox3 acot9 acot9 LOC112145720 LOC112145720 LOC112152159 LOC112152159 ELOVL6 ELOVL6 elovl7 elovl7 ENSOMEP00000035562 ENSOMEP00000035562 ENSOMEP00000035958 ENSOMEP00000035958 LOC112147866 LOC112147866 ENSOMEP00000036321 ENSOMEP00000036321
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSOMEP00000012775Elongation of very long chain fatty acids protein. (292 aa)
elovl5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (294 aa)
ENSOMEP00000001803Hydroxysteroid (20-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa)
LOC112154472Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa)
LOC112151954Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (327 aa)
LOC112160728DEP domain containing 7, paralog a. (517 aa)
LOC112161173Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
acot7Acyl-CoA thioesterase 7. (348 aa)
LOC112137624Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (303 aa)
depdc4Si:ch211-265o23.1. (549 aa)
LOC112150829Abhydrolase domain containing 17A. (319 aa)
LOC112137470Trans-2,3-enoyl-CoA reductase b. (344 aa)
ENSOMEP00000006496BAAT_C domain-containing protein. (204 aa)
bsnUncharacterized protein. (3945 aa)
abhd13Abhydrolase domain containing 13. (351 aa)
acox1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
ENSOMEP00000010365Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (295 aa)
LOC112145803Uncharacterized protein. (476 aa)
LOC112154371Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (333 aa)
LOC112152671DEP domain-containing protein. (555 aa)
ENSOMEP00000014038Si:ch211-117n7.7. (353 aa)
LOC112143893Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (421 aa)
LOC112151473Trans-2,3-enoyl-CoA reductase-like 2a. (328 aa)
ENSOMEP00000017038Fatty acid desaturase 2. (445 aa)
LOC112151777Fatty acid desaturase 2. (442 aa)
LOC112147450Peptidase_S9 domain-containing protein. (351 aa)
hsd17b4Hydroxysteroid (17-beta) dehydrogenase 4. (737 aa)
znf277Zinc finger protein 277. (438 aa)
ENSOMEP00000020703Abhydrolase domain containing 12. (368 aa)
pggt1bProtein geranylgeranyltransferase type I, beta subunit. (364 aa)
hsdl1Hydroxysteroid dehydrogenase like 1. (321 aa)
LOC112158782Acyl-CoA thioesterase 16. (427 aa)
LOC112162957Uncharacterized protein. (423 aa)
ENSOMEP00000021624BAAT_C domain-containing protein. (250 aa)
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (361 aa)
ENSOMEP00000022470SAFB-like, transcription modulator. (901 aa)
hacd1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (242 aa)
hacd4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (224 aa)
LOC112161383Stearoyl-CoA desaturase b; Belongs to the fatty acid desaturase type 1 family. (334 aa)
ENSOMEP00000024663Hydroxysteroid dehydrogenase like 2. (400 aa)
ENSOMEP00000024728Bassoon (presynaptic cytomatrix protein) b. (3240 aa)
LOC112136963Elongation of very long chain fatty acids protein. (264 aa)
tcp11l2T-complex 11, testis-specific-like 2. (523 aa)
LOC112150713Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (346 aa)
ENSOMEP00000025401Trans-2,3-enoyl-CoA reductase a. (286 aa)
elovl6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (272 aa)
abhd17bAbhydrolase domain containing 17B. (288 aa)
ENSOMEP00000027260Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (383 aa)
scp2Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (540 aa)
tcp11l1T-complex 11, testis-specific-like 1. (493 aa)
LOC112138814Uncharacterized protein. (424 aa)
hacd2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (254 aa)
ENSOMEP00000032900Uncharacterized protein. (509 aa)
ENSOMEP00000033023FA_desaturase domain-containing protein. (199 aa)
acox3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (692 aa)
acot9Acyl-CoA thioesterase 9, tandem duplicate 2. (432 aa)
LOC112145720Uncharacterized protein. (466 aa)
LOC112152159Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (357 aa)
ELOVL6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa)
elovl7Elongation of very long chain fatty acids protein. (301 aa)
ENSOMEP00000035562Hydrolase_4 domain-containing protein. (382 aa)
ENSOMEP00000035958Bile_Hydr_Trans domain-containing protein. (269 aa)
LOC112147866Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (314 aa)
ENSOMEP00000036321Uncharacterized protein. (415 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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