STRINGSTRING
pgk1 pgk1 idh3b idh3b got2 got2 LOC112163335 LOC112163335 mat2a mat2a ENSOMEP00000022045 ENSOMEP00000022045 THNSL1 THNSL1 LOC112152414 LOC112152414 idh3a idh3a asnsd1 asnsd1 arg2 arg2 LOC112157466 LOC112157466 LOC112139362 LOC112139362 pgam2 pgam2 ENSOMEP00000019982 ENSOMEP00000019982 tmed8 tmed8 eps8 eps8 ENSOMEP00000019821 ENSOMEP00000019821 asns asns pllp pllp LOC112158822 LOC112158822 PRPSAP1 PRPSAP1 LOC112155227 LOC112155227 LOC112157305 LOC112157305 EPS8L2 EPS8L2 idh3g idh3g ENSOMEP00000016926 ENSOMEP00000016926 LOC112148610 LOC112148610 LOC112144439 LOC112144439 ALDH18A1 ALDH18A1 hsd17b14 hsd17b14 LOC112146039 LOC112146039 LOC112140737 LOC112140737 LOC112162704 LOC112162704 LOC112162694 LOC112162694 cmtm8 cmtm8 ENSOMEP00000014742 ENSOMEP00000014742 tfb1m tfb1m ENSOMEP00000014070 ENSOMEP00000014070 thnsl2 thnsl2 LOC112154057 LOC112154057 ENSOMEP00000013754 ENSOMEP00000013754 ENSOMEP00000013721 ENSOMEP00000013721 ENSOMEP00000013522 ENSOMEP00000013522 LOC112146257 LOC112146257 ENSOMEP00000013085 ENSOMEP00000013085 psat1 psat1 ENSOMEP00000012701 ENSOMEP00000012701 ENSOMEP00000012622 ENSOMEP00000012622 ENSOMEP00000012295 ENSOMEP00000012295 pycr3 pycr3 LOC112139884 LOC112139884 LOC112139889 LOC112139889 LOC112139892 LOC112139892 ENSOMEP00000028217 ENSOMEP00000028217 MYADML2 MYADML2 LOC112155910 LOC112155910 LOC112142403 LOC112142403 ppp1r16a ppp1r16a mal2 mal2 LOC112161998 LOC112161998 ENO2 ENO2 ENSOMEP00000030077 ENSOMEP00000030077 LOC112152743 LOC112152743 LOC112159287 LOC112159287 LOC112153893 LOC112153893 ENSOMEP00000030597 ENSOMEP00000030597 ENSOMEP00000030607 ENSOMEP00000030607 parp6 parp6 atad1 atad1 LOC112145871 LOC112145871 cmtm3 cmtm3 cmtm4 cmtm4 LOC112154386 LOC112154386 ENSOMEP00000032546 ENSOMEP00000032546 ENSOMEP00000032858 ENSOMEP00000032858 ENSOMEP00000033186 ENSOMEP00000033186 LOC112151051 LOC112151051 LOC112154088 LOC112154088 ENSOMEP00000034417 ENSOMEP00000034417 LOC112138568 LOC112138568 ENSOMEP00000034591 ENSOMEP00000034591 LOC112159475 LOC112159475 eno1 eno1 mettl1 mettl1 LOC112156085 LOC112156085 srfbp1 srfbp1 LOC112152846 LOC112152846 tfb2m tfb2m LOC112160154 LOC112160154 ASS1 ASS1 LOC112143273 LOC112143273 myadml2 myadml2 aco2 aco2 LOC112153459 LOC112153459 aco1 aco1 ENSOMEP00000025949 ENSOMEP00000025949 acy1 acy1 LOC112159621 LOC112159621 ENSOMEP00000024638 ENSOMEP00000024638 shmt1 shmt1 eno4 eno4 LOC112155057 LOC112155057 LOC112161965 LOC112161965 ENSOMEP00000001766 ENSOMEP00000001766 cth cth LOC112154502 LOC112154502 phgdh phgdh plp2 plp2 pah pah got1 got1 LOC112143385 LOC112143385 glul glul marveld1 marveld1 PGAM1 PGAM1 LOC112162227 LOC112162227 wrap73 wrap73 rpia rpia ireb2 ireb2 LOC112144728 LOC112144728 dimt1 dimt1 ENSOMEP00000004716 ENSOMEP00000004716 LOC112145710 LOC112145710 TKT TKT crym crym taldo1 taldo1 eno3 eno3 LOC112155487 LOC112155487 pc pc ENSOMEP00000006766 ENSOMEP00000006766 LOC112153841 LOC112153841 asl asl ENSOMEP00000007625 ENSOMEP00000007625 LOC112146519 LOC112146519 ENSOMEP00000008086 ENSOMEP00000008086 LOC112160040 LOC112160040 ENSOMEP00000008238 ENSOMEP00000008238 LOC112147363 LOC112147363 LOC112158687 LOC112158687 ENSOMEP00000008602 ENSOMEP00000008602 LOC112152144 LOC112152144 eif2d eif2d LOC112157190 LOC112157190 LOC112139890 LOC112139890 lgsn lgsn SDS SDS idh1 idh1 GOT1 GOT1 LOC112137599 LOC112137599 ENSOMEP00000011585 ENSOMEP00000011585 IDH2 IDH2 LOC112162058 LOC112162058 LOC112162126 LOC112162126 ENSOMEP00000012213 ENSOMEP00000012213 LOC112153314 LOC112153314 LOC112159311 LOC112159311 ENSOMEP00000023883 ENSOMEP00000023883 LOC112149379 LOC112149379
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pgk1Phosphoglycerate kinase. (417 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (390 aa)
got2Aspartate aminotransferase. (428 aa)
LOC112163335S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (392 aa)
mat2aS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
ENSOMEP00000022045Carbamoyl-phosphate synthase 1, mitochondrial. (1463 aa)
THNSL1Threonine synthase like 1. (717 aa)
LOC112152414Si:dkeyp-66d1.7. (293 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (368 aa)
asnsd1Asparagine synthetase domain containing 1. (604 aa)
arg2Arginase. (373 aa)
LOC112157466MARVEL domain-containing protein. (288 aa)
LOC112139362MARVEL domain-containing protein. (182 aa)
pgam2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (255 aa)
ENSOMEP00000019982N-acetylglutamate synthase. (455 aa)
tmed8Transmembrane p24 trafficking protein 8. (271 aa)
eps8Epidermal growth factor receptor pathway substrate 8a. (825 aa)
ENSOMEP00000019821F420_oxidored domain-containing protein. (312 aa)
asnsAsparagine synthetase [glutamine-hydrolyzing]. (576 aa)
pllpPlasmolipin. (187 aa)
LOC112158822ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
PRPSAP1Phosphoribosyl pyrophosphate synthetase associated protein 1. (370 aa)
LOC112155227Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (587 aa)
LOC112157305Mal, T cell differentiation protein a. (155 aa)
EPS8L2EPS8 like 2. (697 aa)
idh3gIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (392 aa)
ENSOMEP00000016926S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (392 aa)
LOC112148610ATPase family AAA domain containing 1a; Belongs to the AAA ATPase family. (378 aa)
LOC112144439ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (804 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (779 aa)
hsd17b14Hydroxysteroid (17-beta) dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
LOC112146039Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (389 aa)
LOC112140737Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
LOC112162704Triosephosphate isomerase. (248 aa)
LOC112162694Enolase 2. (434 aa)
cmtm8CKLF-like MARVEL transmembrane domain containing 8b. (194 aa)
ENSOMEP00000014742Phosphoserine phosphatase. (278 aa)
tfb1mrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (352 aa)
ENSOMEP00000014070Si:ch73-263o4.3. (318 aa)
thnsl2Threonine synthase-like 2. (511 aa)
LOC112154057Eps8 like 1b. (665 aa)
ENSOMEP00000013754Pyruvate kinase; Belongs to the pyruvate kinase family. (554 aa)
ENSOMEP00000013721Aminotran_1_2 domain-containing protein. (438 aa)
ENSOMEP00000013522Zgc:77748. (275 aa)
LOC112146257Zgc:77748. (284 aa)
ENSOMEP00000013085PTB domain-containing protein. (92 aa)
psat1Phosphoserine aminotransferase 1. (372 aa)
ENSOMEP00000012701Uncharacterized protein. (100 aa)
ENSOMEP00000012622Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
ENSOMEP00000012295Triosephosphate isomerase. (326 aa)
pycr3Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (431 aa)
LOC112139884Uncharacterized protein. (287 aa)
LOC112139889Uncharacterized protein. (293 aa)
LOC112139892Uncharacterized protein. (284 aa)
ENSOMEP00000028217PFK domain-containing protein. (205 aa)
MYADML2Myeloid associated differentiation marker like 2. (310 aa)
LOC112155910Patatin-like phospholipase domain containing 8. (716 aa)
LOC112142403Serine dehydratase-like. (322 aa)
ppp1r16aSi:ch211-217a12.1. (1028 aa)
mal2Mal, T cell differentiation protein 2 (gene/pseudogene). (176 aa)
LOC112161998Mal, T cell differentiation protein b. (177 aa)
ENO2Enolase 2. (434 aa)
ENSOMEP00000030077Poly (ADP-ribose) polymerase family, member 6b. (516 aa)
LOC112152743Pyruvate kinase; Belongs to the pyruvate kinase family. (597 aa)
LOC112159287Transketolase b. (626 aa)
LOC112153893Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (774 aa)
ENSOMEP00000030597Uncharacterized protein. (284 aa)
ENSOMEP00000030607Glutamate-ammonia ligase (glutamine synthase) c; Belongs to the glutamine synthetase family. (273 aa)
parp6Poly [ADP-ribose] polymerase. (642 aa)
atad1ATPase family AAA domain containing 1b; Belongs to the AAA ATPase family. (362 aa)
LOC112145871Eps8 like 1a. (494 aa)
cmtm3CKLF-like MARVEL transmembrane domain containing 3. (171 aa)
cmtm4CKLF-like MARVEL transmembrane domain containing 4. (208 aa)
LOC112154386Uncharacterized protein. (280 aa)
ENSOMEP00000032546Serine hydroxymethyltransferase 2 (mitochondrial). (500 aa)
ENSOMEP00000032858Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (331 aa)
ENSOMEP00000033186Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (320 aa)
LOC112151051ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (788 aa)
LOC112154088Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (366 aa)
ENSOMEP00000034417Gln_synt_b-grasp domain-containing protein; Belongs to the glutamine synthetase family. (191 aa)
LOC112138568Phosphoribosyl pyrophosphate synthetase-associated protein 2. (357 aa)
ENSOMEP00000034591Citrate synthase; Belongs to the citrate synthase family. (471 aa)
LOC112159475EPS8-like 3b. (677 aa)
eno1Enolase 1a, (alpha). (432 aa)
mettl1tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (241 aa)
LOC112156085Si:ch73-132f6.5. (665 aa)
srfbp1Uncharacterized protein. (546 aa)
LOC112152846Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
tfb2mrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (456 aa)
LOC112160154Phosphoribosyl pyrophosphate synthetase 2. (321 aa)
ASS1Argininosuccinate synthase 1. (341 aa)
LOC112143273Pyruvate kinase; Belongs to the pyruvate kinase family. (543 aa)
myadml2Myeloid-associated differentiation marker-like 2. (303 aa)
aco2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
LOC112153459Si:ch211-153b23.3. (871 aa)
aco1Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. (892 aa)
ENSOMEP00000025949Enolase_C domain-containing protein. (203 aa)
acy1Aminoacylase 1. (419 aa)
LOC112159621Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (552 aa)
ENSOMEP00000024638Aminotran_1_2 domain-containing protein. (524 aa)
shmt1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (482 aa)
eno4Enolase 4. (550 aa)
LOC112155057ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
LOC112161965PALP domain-containing protein. (531 aa)
ENSOMEP000000017665-methyltetrahydrofolate-homocysteine methyltransferase. (721 aa)
cthCystathionase (cystathionine gamma-lyase), like. (416 aa)
LOC112154502S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (416 aa)
phgdhD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (527 aa)
plp2Proteolipid protein 2. (172 aa)
pahPhenylalanine hydroxylase. (510 aa)
got1Aspartate aminotransferase. (441 aa)
LOC112143385Si:dkey-12j5.1. (420 aa)
glulGlutamine synthetase. (371 aa)
marveld1MARVEL domain containing 1. (165 aa)
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
LOC112162227S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (387 aa)
wrap73WD repeat containing, antisense to TP73. (449 aa)
rpiaRibose 5-phosphate isomerase A (ribose 5-phosphate epimerase). (271 aa)
ireb2Iron-responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (986 aa)
LOC112144728Transketolase a. (628 aa)
dimt1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (306 aa)
ENSOMEP00000004716CKLF-like MARVEL transmembrane domain containing 7. (155 aa)
LOC112145710Enolase 1b, (alpha). (443 aa)
TKTTransketolase. (628 aa)
crymCrystallin, mu. (315 aa)
taldo1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (345 aa)
eno3Enolase 3, (beta, muscle). (434 aa)
LOC112155487Ribulose-5-phosphate-3-epimerase. (269 aa)
pcPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1179 aa)
ENSOMEP00000006766Phosphoribosyl pyrophosphate synthetase 1B. (402 aa)
LOC112153841Threonine aldolase 1. (426 aa)
aslArgininosuccinate lyase. (490 aa)
ENSOMEP00000007625Phosphofructokinase, muscle b. (713 aa)
LOC112146519Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (321 aa)
ENSOMEP00000008086Uncharacterized protein. (317 aa)
LOC112160040Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (583 aa)
ENSOMEP00000008238Uncharacterized protein. (550 aa)
LOC112147363Glutamic pyruvate transaminase (alanine aminotransferase) 2, like. (515 aa)
LOC112158687Uncharacterized protein. (264 aa)
ENSOMEP00000008602Transcription termination factor, RNA polymerase II. (1088 aa)
LOC112152144PNPLA domain-containing protein. (876 aa)
eif2dEukaryotic translation initiation factor 2D. (590 aa)
LOC112157190Pribosyltran_N domain-containing protein. (383 aa)
LOC112139890Uncharacterized protein. (297 aa)
lgsnLengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (656 aa)
SDSSerine dehydratase. (288 aa)
idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
GOT1Aspartate aminotransferase. (410 aa)
LOC112137599Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (321 aa)
ENSOMEP00000011585Glyceraldehyde-3-phosphate dehydrogenase. (305 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
LOC112162058MARVEL domain-containing protein. (157 aa)
LOC112162126MARVEL domain-containing protein. (156 aa)
ENSOMEP00000012213Arginase. (341 aa)
LOC112153314Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (456 aa)
LOC112159311PNPLA domain-containing protein. (761 aa)
ENSOMEP00000023883Uncharacterized protein. (151 aa)
LOC112149379Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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