STRINGSTRING
LTBP3 LTBP3 acvr1 acvr1 myc myc LOC112161425 LOC112161425 LOC112145637 LOC112145637 ENSOMEP00000000406 ENSOMEP00000000406 ENSOMEP00000031808 ENSOMEP00000031808 pknox1 pknox1 LOC112145685 LOC112145685 LOC112141100 LOC112141100 ENSOMEP00000032207 ENSOMEP00000032207 ENSOMEP00000032211 ENSOMEP00000032211 LOC112141100-2 LOC112141100-2 ENSOMEP00000032268 ENSOMEP00000032268 ENSOMEP00000032284 ENSOMEP00000032284 LOC112141101 LOC112141101 LOC112154809 LOC112154809 INHBC INHBC ENSOMEP00000032745 ENSOMEP00000032745 ENSOMEP00000033103 ENSOMEP00000033103 thbs1 thbs1 ankfn1 ankfn1 ints8 ints8 ENSOMEP00000017278 ENSOMEP00000017278 GREM1 GREM1 LOC112149681 LOC112149681 LOC112141003 LOC112141003 bmp2 bmp2 ENSOMEP00000018249 ENSOMEP00000018249 SMAD3-2 SMAD3-2 smad6 smad6 LOC112144350 LOC112144350 ENSOMEP00000035618 ENSOMEP00000035618 bmpr1a bmpr1a ENSOMEP00000035067 ENSOMEP00000035067 LOC112148478 LOC112148478 RPS6KB2 RPS6KB2 LOC112145435 LOC112145435 ltbp2 ltbp2 ltbp1 ltbp1 LOC112153580 LOC112153580 LOC112151511 LOC112151511 id1 id1 LOC112148176 LOC112148176 LOC112162776 LOC112162776 LOC112149754 LOC112149754 LOC112161005 LOC112161005 ENSOMEP00000019914 ENSOMEP00000019914 zfyve9 zfyve9 bambi bambi tgfb3 tgfb3 LOC112143570 LOC112143570 smad2 smad2 LOC112143136 LOC112143136 e2f4 e2f4 acvr2a acvr2a ENSOMEP00000018504 ENSOMEP00000018504 LOC112146278 LOC112146278 TGFB3 TGFB3 LOC112152993 LOC112152993 ENSOMEP00000016060 ENSOMEP00000016060 LOC112153979 LOC112153979 ACVR1B ACVR1B INHBB INHBB LOC112138696 LOC112138696 THSD4 THSD4 LOC112149899 LOC112149899 fst fst NBL1 NBL1 MATN2 MATN2 ENSOMEP00000013464 ENSOMEP00000013464 LOC112158472 LOC112158472 LOC112159207 LOC112159207 LOC112149994 LOC112149994 LOC112141895 LOC112141895 LOC112158619 LOC112158619 ENSOMEP00000011622 ENSOMEP00000011622 ENSOMEP00000011614 ENSOMEP00000011614 ENSOMEP00000011604 ENSOMEP00000011604 LOC112147395 LOC112147395 ENSOMEP00000011590 ENSOMEP00000011590 ENSOMEP00000011579 ENSOMEP00000011579 ENSOMEP00000011462 ENSOMEP00000011462 LOC112138250 LOC112138250 nodal nodal LOC112143146 LOC112143146 LOC112147850 LOC112147850 pknox2 pknox2 tfdp1 tfdp1 FBN1 FBN1 LOC112139043 LOC112139043 mapk1 mapk1 ENSOMEP00000008032 ENSOMEP00000008032 SMAD3 SMAD3 LOC112153984 LOC112153984 snapin snapin rock1 rock1 fstl3 fstl3 LOC112146480 LOC112146480 LOC112159660 LOC112159660 LOC112139461 LOC112139461 pitx2 pitx2 smad7 smad7 LOC112140009 LOC112140009 LOC112159680 LOC112159680 LOC112143205 LOC112143205 ENSOMEP00000005933 ENSOMEP00000005933 ENSOMEP00000005837 ENSOMEP00000005837 LOC112157283 LOC112157283 LOC112155588 LOC112155588 ENSOMEP00000005452 ENSOMEP00000005452 dcn dcn ENSOMEP00000004856 ENSOMEP00000004856 LOC112158371 LOC112158371 ENSOMEP00000004505 ENSOMEP00000004505 LOC112146043 LOC112146043 LOC112149160 LOC112149160 LOC112144861 LOC112144861 rgmb rgmb smad1 smad1 gdf5 gdf5 skp1 skp1 pitx1 pitx1 ENSOMEP00000002014 ENSOMEP00000002014 ACVR1C ACVR1C bmpr2 bmpr2 LOC112158403 LOC112158403 bmp5 bmp5 bmpr1b bmpr1b bmp6 bmp6 ENSOMEP00000030465 ENSOMEP00000030465 ENSOMEP00000030045 ENSOMEP00000030045 bmp4 bmp4 smad9 smad9 ENSOMEP00000029314 ENSOMEP00000029314 LOC112141952 LOC112141952 id3 id3 LOC112158689 LOC112158689 crebbp crebbp ENSOMEP00000027367 ENSOMEP00000027367 grem2 grem2 ppp2cb ppp2cb SMURF2 SMURF2 ENSOMEP00000026919 ENSOMEP00000026919 LOC112160358 LOC112160358 MATN4 MATN4 id2 id2 TGFBR2 TGFBR2 ldah ldah LOC112146935 LOC112146935 LOC112140741 LOC112140741 cul1 cul1 RHOB RHOB chrd chrd rbx1 rbx1 hjv hjv smurf1 smurf1 amh amh LOC112151615 LOC112151615 LOC112136593 LOC112136593 ENSOMEP00000023886 ENSOMEP00000023886 ppp2ca ppp2ca ENSOMEP00000023058 ENSOMEP00000023058 LOC112163021 LOC112163021 LOC112160553 LOC112160553
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LTBP3Latent transforming growth factor beta binding protein 3. (1242 aa)
acvr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (681 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (427 aa)
LOC112161425Homeobox protein. (294 aa)
LOC112145637Bone morphogenetic protein 7a. (427 aa)
ENSOMEP00000000406Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (478 aa)
ENSOMEP00000031808MYCL proto-oncogene, bHLH transcription factor a. (373 aa)
pknox1Pbx/knotted 1 homeobox 1.1. (437 aa)
LOC112145685Homeobox domain-containing protein. (496 aa)
LOC112141100Uncharacterized protein. (89 aa)
ENSOMEP00000032207Retinoblastoma-like 1 (p107). (1040 aa)
ENSOMEP00000032211Bone morphogenetic protein 8a. (439 aa)
LOC112141100-2Uncharacterized protein. (145 aa)
ENSOMEP00000032268Uncharacterized protein. (1392 aa)
ENSOMEP00000032284Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1089 aa)
LOC112141101Growth differentiation factor 6a. (432 aa)
LOC112154809Inhibin subunit beta B. (385 aa)
INHBCInhibin subunit beta C. (443 aa)
ENSOMEP00000032745MH1 domain-containing protein. (63 aa)
ENSOMEP00000033103Uncharacterized protein. (597 aa)
thbs1Thrombospondin 1a. (1172 aa)
ankfn1Ankyrin repeat and fibronectin type III domain containing 1. (1452 aa)
ints8Integrator complex subunit 8. (995 aa)
ENSOMEP00000017278Growth differentiation factor 6b. (401 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (163 aa)
LOC112149681Uncharacterized protein. (1677 aa)
LOC112141003RGM domain family, member D. (603 aa)
bmp2Bone morphogenetic protein 2b. (408 aa)
ENSOMEP00000018249TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (92 aa)
SMAD3-2Mothers against decapentaplegic homolog. (429 aa)
smad6Mothers against decapentaplegic homolog. (485 aa)
LOC112144350Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (372 aa)
ENSOMEP00000035618BHLH domain-containing protein. (299 aa)
bmpr1aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa)
ENSOMEP00000035067Uncharacterized protein. (197 aa)
LOC112148478Mothers against decapentaplegic homolog. (467 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (494 aa)
LOC112145435Zgc:113307. (366 aa)
ltbp2Uncharacterized protein. (1979 aa)
ltbp1Latent transforming growth factor beta binding protein 1. (1398 aa)
LOC112153580Mothers against decapentaplegic homolog. (464 aa)
LOC112151511Inhibin subunit beta Aa. (457 aa)
id1Inhibitor of DNA binding 1, HLH protein. (129 aa)
LOC112148176Mothers against decapentaplegic homolog. (510 aa)
LOC112162776Zinc finger, FYVE domain containing 16. (1321 aa)
LOC112149754Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
LOC112161005Upstream transcription factor 2, c-fos interacting. (306 aa)
ENSOMEP00000019914TGF_BETA_2 domain-containing protein. (129 aa)
zfyve9Zinc finger, FYVE domain containing 9a. (1164 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (406 aa)
LOC112143570BHLH domain-containing protein. (318 aa)
smad2Mothers against decapentaplegic homolog. (473 aa)
LOC112143136Uncharacterized protein. (91 aa)
e2f4E2F transcription factor 4. (386 aa)
acvr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (525 aa)
ENSOMEP00000018504Fibromodulin a. (316 aa)
LOC112146278Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (389 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
LOC112152993Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
ENSOMEP00000016060Inhibitor of DNA binding 4. (139 aa)
LOC112153979Noggin; Belongs to the noggin family. (212 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
INHBBInhibin subunit beta B. (387 aa)
LOC112138696Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (510 aa)
THSD4Thrombospondin type 1 domain containing 4. (941 aa)
LOC112149899Uncharacterized protein. (457 aa)
fstFollistatin a. (346 aa)
NBL1NBL1, DAN family BMP antagonist. (187 aa)
MATN2Matrilin 2. (755 aa)
ENSOMEP00000013464Protein phosphatase 2, regulatory subunit A, beta b. (647 aa)
LOC112158472Left-right determination factor. (358 aa)
LOC112159207Ras homolog gene family, member Aa. (193 aa)
LOC112149994Bone morphogenetic protein 16. (516 aa)
LOC112141895Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (537 aa)
LOC112158619Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
ENSOMEP00000011622Uncharacterized protein. (595 aa)
ENSOMEP00000011614EGF-like domain-containing protein. (46 aa)
ENSOMEP00000011604EGF-like domain-containing protein. (85 aa)
LOC112147395Anti-dorsalizing morphogenic protein. (381 aa)
ENSOMEP00000011590Uncharacterized protein. (348 aa)
ENSOMEP00000011579Uncharacterized protein. (247 aa)
ENSOMEP00000011462PLAC domain-containing protein. (233 aa)
LOC112138250TGF_BETA_2 domain-containing protein. (414 aa)
nodalNodal-related 2. (378 aa)
LOC112143146Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
LOC112147850E2F transcription factor 5. (362 aa)
pknox2Pbx/knotted 1 homeobox 2. (486 aa)
tfdp1Transcription factor. (413 aa)
FBN1Fibrillin 1. (2877 aa)
LOC112139043Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
ENSOMEP00000008032Matrilin 1. (461 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
LOC112153984E1A binding protein p300 a. (2690 aa)
snapinSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (133 aa)
rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1380 aa)
fstl3Follistatin-like 3 (secreted glycoprotein). (250 aa)
LOC112146480E3 ubiquitin-protein ligase. (770 aa)
LOC112159660Uncharacterized protein. (193 aa)
LOC112139461Tumor necrosis factor a (TNF superfamily, member 2). (236 aa)
pitx2Homeobox protein. (316 aa)
smad7Mothers against decapentaplegic homolog. (375 aa)
LOC112140009Myelocytomatosis oncogene homolog. (366 aa)
LOC112159680Bone morphogenetic protein 7b. (427 aa)
LOC112143205AMOP domain-containing protein. (454 aa)
ENSOMEP00000005933Neogenin 1b. (1459 aa)
ENSOMEP00000005837Uncharacterized protein. (261 aa)
LOC112157283Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (129 aa)
LOC112155588TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (574 aa)
ENSOMEP00000005452Zinc finger, FYVE domain containing 9b. (674 aa)
dcnDecorin; May affect the rate of fibrils formation. (482 aa)
ENSOMEP00000004856Repulsive guidance molecule BMP co-receptor a. (438 aa)
LOC112158371Matrilin 3a. (666 aa)
ENSOMEP00000004505CREB binding protein a. (2295 aa)
LOC112146043E1A binding protein p300 b. (2771 aa)
LOC112149160Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (503 aa)
LOC112144861Uncharacterized protein. (193 aa)
rgmbRepulsive guidance molecule BMP co-receptor b. (465 aa)
smad1Mothers against decapentaplegic homolog. (471 aa)
gdf5Growth differentiation factor 5. (561 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
pitx1Homeobox protein. (316 aa)
ENSOMEP00000002014TGF_BETA_2 domain-containing protein. (364 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1056 aa)
LOC112158403Thrombospondin 1b. (1168 aa)
bmp5Bone morphogenetic protein 5. (454 aa)
bmpr1bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
bmp6Bone morphogenetic protein 6. (425 aa)
ENSOMEP00000030465Noggin; Belongs to the noggin family. (208 aa)
ENSOMEP00000030045TGF_BETA_2 domain-containing protein. (151 aa)
bmp4Bone morphogenetic protein 4. (440 aa)
smad9Mothers against decapentaplegic homolog. (530 aa)
ENSOMEP00000029314Uncharacterized protein. (271 aa)
LOC112141952Si:dkey-222f2.1; Belongs to the intermediate filament family. (446 aa)
id3Inhibitor of DNA binding 3. (117 aa)
LOC112158689Fibromodulin b. (397 aa)
crebbpCREB binding protein b. (2411 aa)
ENSOMEP00000027367TGF_BETA_2 domain-containing protein. (492 aa)
grem2Gremlin 2, DAN family BMP antagonist a. (192 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
SMURF2E3 ubiquitin-protein ligase. (775 aa)
ENSOMEP00000026919PLAC domain-containing protein. (1151 aa)
LOC112160358Mothers against decapentaplegic homolog. (495 aa)
MATN4VWFA domain-containing protein. (329 aa)
id2Inhibitor of DNA binding 2a. (136 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ldahLipid droplet associated hydrolase. (330 aa)
LOC112146935Fibronectin type-III domain-containing protein. (1076 aa)
LOC112140741MYCL proto-oncogene, bHLH transcription factor b. (483 aa)
cul1Cullin 1b; Belongs to the cullin family. (777 aa)
RHOBRas homolog family member B. (149 aa)
chrdChordin; Belongs to the chordin family. (946 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
hjvHemojuvelin BMP co-receptor. (412 aa)
smurf1E3 ubiquitin-protein ligase. (731 aa)
amhAnti-Mullerian hormone. (495 aa)
LOC112151615TGFB-induced factor homeobox 1. (301 aa)
LOC112136593Mothers against decapentaplegic homolog. (536 aa)
ENSOMEP00000023886DCC netrin 1 receptor. (1468 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
ENSOMEP00000023058Mothers against decapentaplegic homolog. (493 aa)
LOC112163021Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
LOC112160553E2F_TDP domain-containing protein. (308 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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