STRINGSTRING
ENSOMEP00000005632 ENSOMEP00000005632 anapc11 anapc11 ENSOMEP00000006129 ENSOMEP00000006129 LOC112149155 LOC112149155 mad2l2 mad2l2 raf1 raf1 CDC25B CDC25B mapk1 mapk1 spdya spdya LOC112147562 LOC112147562 LOC112152429 LOC112152429 LOC112144555 LOC112144555 ENSOMEP00000009829 ENSOMEP00000009829 LOC112153403 LOC112153403 KRAS KRAS LOC112161991 LOC112161991 LOC112158927 LOC112158927 ENSOMEP00000035932 ENSOMEP00000035932 ENSOMEP00000035769 ENSOMEP00000035769 araf araf cdk2 cdk2 cdc23 cdc23 ENSOMEP00000034970 ENSOMEP00000034970 pkmyt1 pkmyt1 ENSOMEP00000034884 ENSOMEP00000034884 pde3b pde3b kif22 kif22 ADCY3 ADCY3 mad1l1 mad1l1 LOC112156435 LOC112156435 LOC112159026 LOC112159026 ENSOMEP00000032841 ENSOMEP00000032841 ENSOMEP00000032690 ENSOMEP00000032690 prkacb prkacb ENSOMEP00000032569 ENSOMEP00000032569 ENSOMEP00000032467 ENSOMEP00000032467 anapc5 anapc5 adcy5 adcy5 LOC112146394 LOC112146394 ENSOMEP00000031513 ENSOMEP00000031513 adcy7 adcy7 ENSOMEP00000031347 ENSOMEP00000031347 pik3r1 pik3r1 anapc2 anapc2 cdc16 cdc16 ENSOMEP00000029714 ENSOMEP00000029714 LOC112153519 LOC112153519 PIK3CA PIK3CA ENSOMEP00000027649 ENSOMEP00000027649 ADCY9 ADCY9 mapk8 mapk8 LOC112147217 LOC112147217 LOC112138447 LOC112138447 LOC112147013 LOC112147013 REM1 REM1 LOC112158536 LOC112158536 LOC112138526 LOC112138526 LOC112157322 LOC112157322 ENSOMEP00000025532 ENSOMEP00000025532 LOC112147412 LOC112147412 CPEB4 CPEB4 LOC112153234 LOC112153234 ENSOMEP00000024440 ENSOMEP00000024440 LOC112137228 LOC112137228 LOC112142690 LOC112142690 LOC112147429 LOC112147429 mad2l1 mad2l1 LOC112161471 LOC112161471 LOC112145165 LOC112145165 pgr pgr ENSOMEP00000021566 ENSOMEP00000021566 ENSOMEP00000021559 ENSOMEP00000021559 LOC112139315 LOC112139315 LOC112152089 LOC112152089 pik3cd pik3cd map2k1 map2k1 LOC112158895 LOC112158895 FZR1 FZR1 cdc26 cdc26 adcy8 adcy8 LOC112158855 LOC112158855 anapc13 anapc13 PLK1 PLK1 LOC112158959 LOC112158959 LOC112146278 LOC112146278 akt1 akt1 bub1 bub1 aurka aurka rrad rrad ENSOMEP00000015819 ENSOMEP00000015819 LOC112140005 LOC112140005 ccnb1 ccnb1 LOC112159424 LOC112159424 pik3r3 pik3r3 cdc27 cdc27 LOC112150580 LOC112150580 LOC112153155 LOC112153155 LOC112143511 LOC112143511 ENSOMEP00000012192 ENSOMEP00000012192 ENSOMEP00000011806 ENSOMEP00000011806 ccna1 ccna1 ins ins cdk1 cdk1 ccna2 ccna2 ccnb2 ccnb2 ENSOMEP00000002349 ENSOMEP00000002349 igf1 igf1 LOC112161131 LOC112161131 gem gem LOC112158166 LOC112158166 ENSOMEP00000003528 ENSOMEP00000003528 braf braf stk10 stk10 ap5s1 ap5s1 LOC112137465 LOC112137465 LOC112147433 LOC112147433 LOC112152311 LOC112152311 adcy6 adcy6 prkaca prkaca cpeb1 cpeb1 LOC112146515 LOC112146515
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSOMEP00000005632Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (483 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
ENSOMEP00000006129Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1078 aa)
LOC112149155Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (412 aa)
mad2l2Mitotic arrest deficient 2 like 2. (210 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase a. (677 aa)
CDC25BCell division cycle 25B. (572 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
spdyaSpeedy/RINGO cell cycle regulator family member A. (317 aa)
LOC112147562Uncharacterized protein. (466 aa)
LOC112152429Uncharacterized protein. (354 aa)
LOC112144555Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a. (355 aa)
ENSOMEP00000009829Non-specific serine/threonine protein kinase. (592 aa)
LOC112153403Cytoplasmic polyadenylation element binding protein 4a. (741 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
LOC112161991Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC112158927IlGF domain-containing protein. (181 aa)
ENSOMEP00000035932Mitogen-activated protein kinase. (351 aa)
ENSOMEP00000035769Heat shock protein 90, alpha (cytosolic), class B member 1. (724 aa)
arafA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (642 aa)
ENSOMEP00000034970Anaphase promoting complex subunit 7. (565 aa)
pkmyt1Protein kinase, membrane associated tyrosine/threonine 1. (565 aa)
ENSOMEP00000034884Cyclin B3; Belongs to the cyclin family. (347 aa)
pde3bPhosphodiesterase. (1102 aa)
kif22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (623 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1105 aa)
mad1l1Mitotic arrest deficient 1 like 1. (722 aa)
LOC112156435Uncharacterized protein. (1276 aa)
LOC112159026Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1179 aa)
ENSOMEP00000032841Tyrosine-protein kinase receptor. (1405 aa)
ENSOMEP00000032690Cytoplasmic polyadenylation element binding protein 3. (681 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
ENSOMEP00000032569Adenylate cyclase 3b; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (357 aa)
ENSOMEP00000032467Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (539 aa)
anapc5Anaphase promoting complex subunit 5. (773 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1196 aa)
LOC112146394Zgc:55558. (186 aa)
ENSOMEP00000031513ANAPC4_WD40 domain-containing protein. (206 aa)
adcy7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1099 aa)
ENSOMEP00000031347Aurora kinase B; Belongs to the protein kinase superfamily. (312 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (806 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (618 aa)
ENSOMEP00000029714Protein kinase domain-containing protein. (102 aa)
LOC112153519Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSOMEP00000027649V-mos Moloney murine sarcoma viral oncogene homolog; Belongs to the protein kinase superfamily. (262 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1419 aa)
mapk8Mitogen-activated protein kinase. (384 aa)
LOC112147217Fizzy/cell division cycle 20 related 1b. (487 aa)
LOC112138447Uncharacterized protein. (716 aa)
LOC112147013Uncharacterized protein. (371 aa)
REM1RRAD and GEM like GTPase 1. (306 aa)
LOC112158536Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1187 aa)
LOC112138526Transmembrane protein 82. (337 aa)
LOC112157322Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ENSOMEP00000025532Mitogen-activated protein kinase. (402 aa)
LOC112147412Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CPEB4Cytoplasmic polyadenylation element binding protein 4. (750 aa)
LOC112153234Mitogen-activated protein kinase. (420 aa)
ENSOMEP00000024440Cytoplasmic polyadenylation element binding protein 2. (761 aa)
LOC112137228Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (733 aa)
LOC112142690Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (104 aa)
LOC112147429Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1153 aa)
mad2l1MAD2 mitotic arrest deficient-like 1 (yeast). (202 aa)
LOC112161471Mitogen-activated protein kinase. (438 aa)
LOC112145165Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b. (355 aa)
pgrProgesterone receptor. (667 aa)
ENSOMEP00000021566Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (217 aa)
ENSOMEP00000021559Mitogen-activated protein kinase 12b. (358 aa)
LOC112139315Mitogen-activated protein kinase. (361 aa)
LOC112152089Mitogen-activated protein kinase. (361 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
LOC112158895Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (498 aa)
cdc26Cell division cycle 26 homolog. (93 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1228 aa)
LOC112158855Mitogen-activated protein kinase. (360 aa)
anapc13Anaphase promoting complex subunit 13. (74 aa)
PLK1Serine/threonine-protein kinase PLK. (582 aa)
LOC112158959Ribosomal protein S6 kinase. (734 aa)
LOC112146278Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (389 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
bub1BUB1 mitotic checkpoint serine/threonine kinase. (1124 aa)
aurkaAurora kinase A; Belongs to the protein kinase superfamily. (427 aa)
rradRas-related associated with diabetes. (458 aa)
ENSOMEP00000015819Protein kinase domain-containing protein. (358 aa)
LOC112140005Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ccnb1Cyclin B1; Belongs to the cyclin family. (400 aa)
LOC112159424Mitogen-activated protein kinase. (363 aa)
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (723 aa)
cdc27Cell division cycle 27. (802 aa)
LOC112150580Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1114 aa)
LOC112153155Ribosomal protein S6 kinase. (727 aa)
LOC112143511Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1203 aa)
ENSOMEP00000012192Adenylate cyclase 2b (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (826 aa)
ENSOMEP00000011806Anaphase promoting complex subunit 1. (1855 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (457 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (113 aa)
cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (431 aa)
ccnb2Cyclin B2; Belongs to the cyclin family. (394 aa)
ENSOMEP00000002349Uncharacterized protein. (585 aa)
igf1Insulin-like growth factor 1. (184 aa)
LOC112161131Ribosomal protein S6 kinase. (746 aa)
gemGTP binding protein overexpressed in skeletal muscle. (305 aa)
LOC112158166Uncharacterized protein. (354 aa)
ENSOMEP00000003528Transmembrane protein 82. (317 aa)
brafB-Raf proto-oncogene, serine/threonine kinase. (781 aa)
stk10Serine/threonine kinase 10. (1026 aa)
ap5s1Adaptor related protein complex 5 subunit sigma 1. (200 aa)
LOC112137465Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1453 aa)
LOC112147433Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
LOC112152311Tyrosine-protein kinase receptor. (1413 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
prkacaUncharacterized protein; Belongs to the protein kinase superfamily. (359 aa)
cpeb1Cytoplasmic polyadenylation element binding protein 1b. (588 aa)
LOC112146515Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (377 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
Server load: low (18%) [HD]