STRINGSTRING
ARAM_005523 ARAM_005523 ARAM_004215 ARAM_004215 ARAM_002607 ARAM_002607 ARAM_003729 ARAM_003729 ARAM_000418 ARAM_000418 ARAM_000400 ARAM_000400 ARAM_003089 ARAM_003089 ARAM_002522 ARAM_002522 CIA1 CIA1 ARAM_001213 ARAM_001213 ARAM_003210 ARAM_003210 NBP35 NBP35 ARAM_002268 ARAM_002268 ARAM_007224 ARAM_007224 ARAM_006560 ARAM_006560 ARAM_005977 ARAM_005977 ARAM_000860 ARAM_000860 ARAM_006489 ARAM_006489 ARAM_000412 ARAM_000412 ARAM_000417 ARAM_000417 ARAM_000952 ARAM_000952 ARAM_000823 ARAM_000823 ARAM_000193 ARAM_000193 ARAM_003037 ARAM_003037 TAH18 TAH18 ARAM_001245 ARAM_001245 ARAM_006073 ARAM_006073 ARAM_000061 ARAM_000061 ARAM_005203 ARAM_005203 ARAM_007076 ARAM_007076 ARAM_001495 ARAM_001495 ARAM_007514 ARAM_007514 DRE2 DRE2 ARAM_006445 ARAM_006445 CFD1 CFD1 ARAM_004749 ARAM_004749 ARAM_000407 ARAM_000407 ARAM_001343 ARAM_001343 ARAM_004817 ARAM_004817 ARAM_001221 ARAM_001221 ARAM_000817 ARAM_000817 ARAM_005718 ARAM_005718 ARAM_000155 ARAM_000155 ARAM_000464 ARAM_000464 ARAM_004909 ARAM_004909 ARAM_004326 ARAM_004326 ARAM_000487 ARAM_000487 ARAM_003146 ARAM_003146 ARAM_000965 ARAM_000965 ARAM_002251 ARAM_002251
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARAM_005523Uncharacterized protein. (339 aa)
ARAM_004215Coproporphyrinogen III oxidase, mitochondrial. (388 aa)
ARAM_002607Yae1_N domain-containing protein. (218 aa)
ARAM_003729BPL/LPL catalytic domain-containing protein. (435 aa)
ARAM_000418Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (293 aa)
ARAM_000400Uncharacterized protein; Belongs to the complex I LYR family. (900 aa)
ARAM_003089Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (143 aa)
ARAM_002522PHD-type domain-containing protein. (1065 aa)
CIA1Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (455 aa)
ARAM_001213Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (341 aa)
ARAM_003210BolA domain protein; Belongs to the BolA/IbaG family. (113 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (342 aa)
ARAM_002268FeS_assembly_P domain-containing protein. (204 aa)
ARAM_007224Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (420 aa)
ARAM_006560Putative thioredoxin. (275 aa)
ARAM_005977Aminotran_5 domain-containing protein. (458 aa)
ARAM_000860NifU-related protein. (256 aa)
ARAM_006489Yae1_N domain-containing protein. (202 aa)
ARAM_000412Uncharacterized protein; Belongs to the precorrin methyltransferase family. (564 aa)
ARAM_000417Putative_PNPOx domain-containing protein. (241 aa)
ARAM_000952Iron sulfur assembly protein. (243 aa)
ARAM_000823HEM4 domain-containing protein. (257 aa)
ARAM_000193Fe_hyd_lg_C domain-containing protein; Belongs to the NARF family. (605 aa)
ARAM_003037Uroporphyrinogen decarboxylase. (378 aa)
TAH18NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (648 aa)
ARAM_001245PKS_ER domain-containing protein. (424 aa)
ARAM_006073Uncharacterized protein. (275 aa)
ARAM_000061tRNA splicing protein. (509 aa)
ARAM_005203J domain-containing protein. (280 aa)
ARAM_007076RNA-splicing protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
ARAM_001495Iron-sulfur protein. (331 aa)
ARAM_007514Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (373 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (305 aa)
ARAM_006445Uncharacterized protein. (344 aa)
CFD1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (338 aa)
ARAM_004749Putative siroheme synthase Met8. (238 aa)
ARAM_000407Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (423 aa)
ARAM_001343Putative aminomethyl transferase. (446 aa)
ARAM_004817Uncharacterized protein. (926 aa)
ARAM_001221CVNH domain-containing protein. (89 aa)
ARAM_000817Iron-sulfur clusters transporter atm1. (689 aa)
ARAM_005718Fe-S_biosyn domain-containing protein. (234 aa)
ARAM_000155Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (334 aa)
ARAM_000464Uncharacterized protein. (317 aa)
ARAM_004909Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (163 aa)
ARAM_004326Uncharacterized protein. (407 aa)
ARAM_000487DNA repair/transcription protein. (1064 aa)
ARAM_003146Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (602 aa)
ARAM_000965Uncharacterized protein. (207 aa)
ARAM_002251BolA domain protein; Belongs to the BolA/IbaG family. (139 aa)
Your Current Organism:
Aspergillus rambellii
NCBI taxonomy Id: 308745
Other names: A. rambellii, ATCC 42001, CBS 101887, IBT 14580
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.