STRINGSTRING
ARAM_007458 ARAM_007458 ARAM_007662 ARAM_007662 ARAM_003123 ARAM_003123 ARAM_004940 ARAM_004940 ARAM_007220 ARAM_007220 ARAM_007064 ARAM_007064 ARAM_000425 ARAM_000425 ARAM_007188 ARAM_007188 ARAM_002567 ARAM_002567 ARAM_003700 ARAM_003700 ARAM_004188 ARAM_004188 ARAM_004187 ARAM_004187 ARAM_003605 ARAM_003605 ARAM_004591 ARAM_004591 ARAM_005196 ARAM_005196 ARAM_000158 ARAM_000158 ARAM_005229 ARAM_005229 ARAM_000886 ARAM_000886 ARAM_005009 ARAM_005009 ARAM_005379 ARAM_005379 ARAM_001516 ARAM_001516 ARAM_005363 ARAM_005363 ARAM_006438 ARAM_006438 ARAM_001977 ARAM_001977 ARAM_006394 ARAM_006394 FEN1 FEN1 ARAM_002616 ARAM_002616 ARAM_006790 ARAM_006790 ARAM_000452 ARAM_000452 ARAM_001944 ARAM_001944 ARAM_001405 ARAM_001405 ARAM_006863 ARAM_006863 ARAM_005194 ARAM_005194 ARAM_000167 ARAM_000167 ARAM_006541 ARAM_006541 ARAM_006564 ARAM_006564 ARAM_005754 ARAM_005754 ARAM_005574 ARAM_005574 ARAM_002150 ARAM_002150 ARAM_000052 ARAM_000052 ARAM_007279 ARAM_007279 ARAM_004928 ARAM_004928 ARAM_000076 ARAM_000076 ARAM_007219 ARAM_007219 ARAM_007015 ARAM_007015 ARAM_001394 ARAM_001394 ARAM_001868 ARAM_001868 ARAM_001263 ARAM_001263 ARAM_002795 ARAM_002795 ARAM_003283 ARAM_003283 ARAM_004186 ARAM_004186 ARAM_005601 ARAM_005601 ARAM_004059 ARAM_004059 ARAM_004432 ARAM_004432 ARAM_004005 ARAM_004005 ARAM_001045 ARAM_001045 ARAM_004260 ARAM_004260
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARAM_0074583'-5' exonuclease domain-containing protein. (356 aa)
ARAM_007662Helicase ATP-binding domain-containing protein. (334 aa)
ARAM_003123Replication factor C subunit 4. (352 aa)
ARAM_004940DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (450 aa)
ARAM_007220DNA-directed polymerase kappa. (610 aa)
ARAM_007064DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa)
ARAM_000425DNA polymerase. (1707 aa)
ARAM_007188Uncharacterized protein. (420 aa)
ARAM_002567AAA domain-containing protein. (779 aa)
ARAM_003700Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2475 aa)
ARAM_004188DNA repair protein. (77 aa)
ARAM_004187Uncharacterized protein. (388 aa)
ARAM_003605UmuC domain-containing protein. (556 aa)
ARAM_004591Uncharacterized protein; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (1363 aa)
ARAM_005196Replication factor C subunit 1. (1054 aa)
ARAM_000158DNA repair protein. (860 aa)
ARAM_005229Serine/threonine-protein. (514 aa)
ARAM_000886DNA ligase. (851 aa)
ARAM_005009DNA repair protein; Belongs to the RecA family. (585 aa)
ARAM_005379Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2911 aa)
ARAM_001516Uncharacterized protein. (541 aa)
ARAM_005363UmuC domain-containing protein. (677 aa)
ARAM_006438Uncharacterized protein. (763 aa)
ARAM_001977Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (607 aa)
ARAM_006394Protein kinase domain-containing protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (1132 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
ARAM_002616Uncharacterized protein. (573 aa)
ARAM_006790Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (899 aa)
ARAM_000452Uncharacterized protein. (837 aa)
ARAM_001944Uncharacterized protein. (1485 aa)
ARAM_001405DNA polymerase. (1100 aa)
ARAM_006863DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1077 aa)
ARAM_005194Replication factor C subunit 5. (352 aa)
ARAM_000167Uncharacterized protein. (1655 aa)
ARAM_006541AAA domain-containing protein. (1320 aa)
ARAM_006564Uncharacterized protein. (971 aa)
ARAM_005754Uncharacterized protein. (768 aa)
ARAM_005574Checkpoint protein; Belongs to the HUS1 family. (358 aa)
ARAM_002150XPGI domain-containing protein. (761 aa)
ARAM_000052Rhodanese domain-containing protein. (145 aa)
ARAM_007279DUF1767 domain-containing protein. (244 aa)
ARAM_004928Uncharacterized protein; Belongs to the RecA family. (337 aa)
ARAM_000076Rad51 domain-containing protein. (426 aa)
ARAM_007219FHA domain-containing protein. (736 aa)
ARAM_007015Uncharacterized protein. (906 aa)
ARAM_001394Uncharacterized protein. (440 aa)
ARAM_001868DNA ligase. (831 aa)
ARAM_001263Mitotic spindle checkpoint protein. (288 aa)
ARAM_002795BRCT domain-containing protein. (1436 aa)
ARAM_003283RECA_2 domain-containing protein. (554 aa)
ARAM_004186DNA repair protein. (1346 aa)
ARAM_005601Protein kinase domain-containing protein. (535 aa)
ARAM_004059Uncharacterized protein. (594 aa)
ARAM_004432AAA domain-containing protein. (388 aa)
ARAM_004005RECA_2 domain-containing protein. (384 aa)
ARAM_001045RPA_C domain-containing protein. (286 aa)
ARAM_004260Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (793 aa)
Your Current Organism:
Aspergillus rambellii
NCBI taxonomy Id: 308745
Other names: A. rambellii, ATCC 42001, CBS 101887, IBT 14580
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