(60 nodes) Dicarboxylic acid metabolic process network (Aspergillus rambellii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	ARAM_003730	Chorismate synthase. (410 aa)
	ARAM_004604	Zn(2)-C6 fungal-type domain-containing protein. (1882 aa)
	ARAM_001611	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (497 aa)
	ARAM_004683	Chorismate mutase. (267 aa)
	ARAM_000429	Aspartate-semialdehyde dehydrogenase. (363 aa)
	ARAM_001783	FolB domain-containing protein. (381 aa)
	ARAM_007512	Extracellular developmental signal biosynthesis protein; Belongs to the glutamine synthetase family. (1386 aa)
	ARAM_004491	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
	ARAM_003670	Aspartate aminotransferase. (394 aa)
	ARAM_005317	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (345 aa)
	ARAM_004882	Quinate dehydrogenase. (338 aa)
	ARAM_003112	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (424 aa)
	ARAM_004974	Ornithine aminotransferase. (466 aa)
	ARAM_002107	Glutamine amidotransferase type-1 domain-containing protein. (2958 aa)
	ARAM_002403	Succinate-semialdehyde dehydrogenase. (495 aa)
	ARAM_006090	Uncharacterized protein. (120 aa)
	ARAM_007706	Uncharacterized protein. (196 aa)
	ARAM_003682	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (460 aa)
	ARAM_003689	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (413 aa)
	ARAM_003133	Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (354 aa)
	ARAM_002767	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (471 aa)
	ARAM_005918	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (434 aa)
	ARAM_005989	Uncharacterized protein. (893 aa)
	ARAM_001080	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (481 aa)
	ARAM_003345	Succinate-semialdehyde dehydrogenase. (536 aa)
	ARAM_007788	Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (364 aa)
	ARAM_001931	Uncharacterized protein. (124 aa)
	ARAM_005595	Nitrilase family protein. (293 aa)
	ARAM_004878	Uncharacterized protein. (913 aa)
	ARAM_005021	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (400 aa)
	ARAM_005649	Transket_pyr domain-containing protein. (1055 aa)
	ARAM_005530	Uncharacterized protein. (263 aa)
	ARAM_005109	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1095 aa)
	BNA5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (486 aa)
	ARAM_000044	Folic acid synthesis protein. (464 aa)
	ARAM_001164	Uncharacterized protein. (805 aa)
	ARAM_000848	GTP cyclohydrolase I. (333 aa)
	ARAM_006929	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (519 aa)
	ARAM_007579	Aldedh domain-containing protein. (157 aa)
	BNA1	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (182 aa)
	ARAM_004745	Malate dehydrogenase. (339 aa)
	ARAM_006695	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (278 aa)
	ARAM_005207	3-hydroxyanthranilate 3,4-dioxygenase. (151 aa)
	ARAM_001078	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (572 aa)
	ARAM_003668	Putative fumarate hydratase. (545 aa)
	ARAM_007511	Malic enzyme. (571 aa)
	ARAM_003679	Malic enzyme. (575 aa)
	ARAM_002044	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (515 aa)
	ARAM_005988	Glutamine amidotransferase type-2 domain-containing protein. (1213 aa)
	ARAM_000975	Aspartate aminotransferase. (429 aa)
	BNA5-2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (464 aa)
	ARAM_004695	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1585 aa)
	BNA4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (511 aa)
	ARAM_007704	Aspartate aminotransferase. (168 aa)
	ARAM_006218	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (321 aa)
	ARAM_007034	Putative maleylacetate reductase. (167 aa)
	ARAM_006044	Uncharacterized protein. (177 aa)
	ARAM_000309	WAPL domain-containing protein. (697 aa)
	ARAM_001126	Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (116 aa)
	ARAM_000059	Aminotran_1_2 domain-containing protein. (312 aa)

Your Current Organism:

Aspergillus rambellii

NCBI taxonomy Id: 308745
Other names: A. rambellii, ATCC 42001, CBS 101887, IBT 14580

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARAM_000044	ARAM_000848	A0A0F8VV29	A0A0F8W756	Folic acid synthesis protein.	GTP cyclohydrolase I.	0.976
ARAM_000044	ARAM_002107	A0A0F8VV29	A0A0F8UQZ8	Folic acid synthesis protein.	Glutamine amidotransferase type-1 domain-containing protein.	0.806
ARAM_000044	ARAM_002767	A0A0F8VV29	A0A0F8V015	Folic acid synthesis protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.725
ARAM_000044	ARAM_003689	A0A0F8VV29	A0A0F8UX77	Folic acid synthesis protein.	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.	0.988
ARAM_000044	ARAM_005530	A0A0F8VV29	A0A0F8VMX4	Folic acid synthesis protein.	Uncharacterized protein.	0.908
ARAM_000044	ARAM_006695	A0A0F8VV29	A0A0F8WZ20	Folic acid synthesis protein.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.630
ARAM_000044	ARAM_006929	A0A0F8VV29	A0A0F8WAT9	Folic acid synthesis protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.725
ARAM_000059	ARAM_000309	A0A0F8XU74	A0A0F8XT83	Aminotran_1_2 domain-containing protein.	WAPL domain-containing protein.	0.774
ARAM_000059	ARAM_000975	A0A0F8XU74	A0A0F8X9G7	Aminotran_1_2 domain-containing protein.	Aspartate aminotransferase.	0.936
ARAM_000059	ARAM_001078	A0A0F8XU74	A0A0F8X1K0	Aminotran_1_2 domain-containing protein.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.890
ARAM_000059	ARAM_002044	A0A0F8XU74	A0A0F8X891	Aminotran_1_2 domain-containing protein.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.832
ARAM_000059	ARAM_002107	A0A0F8XU74	A0A0F8UQZ8	Aminotran_1_2 domain-containing protein.	Glutamine amidotransferase type-1 domain-containing protein.	0.480
ARAM_000059	ARAM_002403	A0A0F8XU74	A0A0F8URE4	Aminotran_1_2 domain-containing protein.	Succinate-semialdehyde dehydrogenase.	0.457
ARAM_000059	ARAM_003112	A0A0F8XU74	A0A0F8UL94	Aminotran_1_2 domain-containing protein.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.876
ARAM_000059	ARAM_003133	A0A0F8XU74	A0A0F8UZY9	Aminotran_1_2 domain-containing protein.	Malate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.923
ARAM_000059	ARAM_003345	A0A0F8XU74	A0A0F8V3B8	Aminotran_1_2 domain-containing protein.	Succinate-semialdehyde dehydrogenase.	0.457
ARAM_000059	ARAM_003668	A0A0F8XU74	A0A0F8X4G0	Aminotran_1_2 domain-containing protein.	Putative fumarate hydratase.	0.887
ARAM_000059	ARAM_003670	A0A0F8XU74	A0A0F8UFT8	Aminotran_1_2 domain-containing protein.	Aspartate aminotransferase.	0.836
ARAM_000059	ARAM_003679	A0A0F8XU74	A0A0F8X7R0	Aminotran_1_2 domain-containing protein.	Malic enzyme.	0.493
ARAM_000059	ARAM_003682	A0A0F8XU74	A0A0F8UX72	Aminotran_1_2 domain-containing protein.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.908