STRINGSTRING
ARAM_004903 ARAM_004903 ARAM_000871 ARAM_000871 ARAM_004186 ARAM_004186 ARAM_006459 ARAM_006459 ARAM_003298 ARAM_003298 ARAM_004270 ARAM_004270 ARAM_006007 ARAM_006007 ARAM_005103 ARAM_005103 ARAM_007263 ARAM_007263 ARAM_000164 ARAM_000164 ARAM_006755 ARAM_006755 ARAM_003462 ARAM_003462 ARAM_003501 ARAM_003501 ARAM_001300 ARAM_001300 ARAM_005507 ARAM_005507 ARAM_001428 ARAM_001428 ARAM_001976 ARAM_001976 ARAM_000121 ARAM_000121 ARAM_003142 ARAM_003142 ARAM_001031 ARAM_001031 ARAM_006342 ARAM_006342 ARAM_005116 ARAM_005116 ARAM_007390 ARAM_007390 ARAM_004260 ARAM_004260 ARAM_005399 ARAM_005399 ARAM_000440 ARAM_000440 ARAM_007201 ARAM_007201 ARAM_007458 ARAM_007458 ARAM_000934 ARAM_000934 ARAM_000891 ARAM_000891 ARAM_005525 ARAM_005525 ARAM_000838 ARAM_000838 ARAM_000850 ARAM_000850 ARAM_001664 ARAM_001664 ARAM_007452 ARAM_007452 ARAM_006844 ARAM_006844 ARAM_005453 ARAM_005453 ARAM_006209 ARAM_006209 ARAM_002794 ARAM_002794 ARAM_000735 ARAM_000735 ARAM_000509 ARAM_000509 ARAM_006901 ARAM_006901 ARAM_001860 ARAM_001860 ARAM_006654 ARAM_006654 ARAM_004188 ARAM_004188 ARAM_004187 ARAM_004187 ARAM_001215 ARAM_001215 ARAM_004298 ARAM_004298 ARAM_007727 ARAM_007727 ARAM_004053 ARAM_004053 ARAM_005434 ARAM_005434 ARAM_004583 ARAM_004583 ARAM_004036 ARAM_004036 ARAM_004649 ARAM_004649 ARAM_000330 ARAM_000330 ARAM_004855 ARAM_004855 ARAM_001387 ARAM_001387 USB1 USB1 ARAM_005804 ARAM_005804 ARAM_004671 ARAM_004671 ARAM_005697 ARAM_005697 ARAM_007625 ARAM_007625 ARAM_005129 ARAM_005129 ARAM_002000 ARAM_002000 ARAM_003515 ARAM_003515 ARAM_006661 ARAM_006661 ARAM_000841 ARAM_000841 ARAM_004218 ARAM_004218 ARAM_005511 ARAM_005511 ARAM_006421 ARAM_006421 ARAM_000773 ARAM_000773 ARAM_005545 ARAM_005545 ARAM_006416 ARAM_006416 ARAM_002850 ARAM_002850 ARAM_003433 ARAM_003433 ARAM_005367 ARAM_005367 ARAM_006438 ARAM_006438 ARAM_001967 ARAM_001967 ARAM_000111 ARAM_000111 ARAM_006832 ARAM_006832 ARAM_006400 ARAM_006400 ARAM_000690 ARAM_000690 ARAM_006697 ARAM_006697 ARAM_005206 ARAM_005206 ARAM_002195 ARAM_002195 PAN2 PAN2 ARAM_000478 ARAM_000478 FEN1 FEN1 ARAM_006461 ARAM_006461 SLX1 SLX1 ARAM_003840 ARAM_003840 ARAM_004694 ARAM_004694 ARAM_000385 ARAM_000385 ARAM_000376 ARAM_000376 ARAM_002368 ARAM_002368 ARAM_007082 ARAM_007082 ARAM_001283 ARAM_001283 ARAM_004388 ARAM_004388 ARAM_001405 ARAM_001405 ARAM_004781 ARAM_004781 ARAM_001643 ARAM_001643 ARAM_005444 ARAM_005444 ARAM_004366 ARAM_004366 ARAM_005873 ARAM_005873 ARAM_000168 ARAM_000168 ARAM_000167 ARAM_000167 ARAM_000326 ARAM_000326 ARAM_003825 ARAM_003825 ARAM_005091 ARAM_005091 ARAM_005222 ARAM_005222 ARAM_002891 ARAM_002891 ARAM_005894 ARAM_005894 ARAM_002150 ARAM_002150 ARAM_002363 ARAM_002363 ARAM_007389 ARAM_007389 ARAM_007250 ARAM_007250 ARAM_003847 ARAM_003847 ARAM_000492 ARAM_000492 ARAM_000247 ARAM_000247 ARAM_001242 ARAM_001242 ARAM_002341 ARAM_002341 ARAM_002620 ARAM_002620 ARAM_003795 ARAM_003795 ARAM_004999 ARAM_004999 ARAM_002333 ARAM_002333 ARAM_003126 ARAM_003126 ARAM_002308 ARAM_002308 ARAM_005377 ARAM_005377 ARAM_002792 ARAM_002792 ARAM_001795 ARAM_001795 ARAM_005171 ARAM_005171 ARAM_003234 ARAM_003234 ARAM_004031 ARAM_004031 ARAM_001214 ARAM_001214 ARAM_004303 ARAM_004303 ARAM_001867 ARAM_001867 ARAM_004962 ARAM_004962 ARAM_001999 ARAM_001999 ARAM_001979 ARAM_001979 ARAM_006029 ARAM_006029 NTH1 NTH1 ARAM_003213 ARAM_003213 ARAM_005298 ARAM_005298 ARAM_004317 ARAM_004317 ARAM_003981 ARAM_003981 ARAM_004661 ARAM_004661 ARAM_002800 ARAM_002800 ARAM_001436 ARAM_001436 ARAM_001765 ARAM_001765 ARAM_002776 ARAM_002776 ARAM_006561 ARAM_006561 ARAM_001344 ARAM_001344 ARAM_003432 ARAM_003432 ARAM_005152 ARAM_005152 SLX4 SLX4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARAM_004903RNA polymerase II transcription elongation factor Rtf1p. (607 aa)
ARAM_000871Lactamase_B domain-containing protein. (855 aa)
ARAM_004186DNA repair protein. (1346 aa)
ARAM_006459Uncharacterized protein. (232 aa)
ARAM_003298Crossover junction endonuclease mus81. (814 aa)
ARAM_004270Uncharacterized protein. (279 aa)
ARAM_006007zf-C2HE domain-containing protein. (267 aa)
ARAM_005103Heterogeneous nuclear ribonucleoprotein. (554 aa)
ARAM_007263tRNA(M5U54)methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (586 aa)
ARAM_000164Mitotic control protein; Belongs to the RNR ribonuclease family. (1035 aa)
ARAM_006755Putative ATP dependent RNA helicase (Dob1). (1088 aa)
ARAM_003462Putative ribonuclease P complex subunit Pop2. (310 aa)
ARAM_003501Eukaryotic translation initiation factor 2c. (896 aa)
ARAM_001300Nuclease domain-containing protein. (1292 aa)
ARAM_005507BZIP domain-containing protein. (1863 aa)
ARAM_001428DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
ARAM_001976Uncharacterized protein; Belongs to the DEAD box helicase family. (490 aa)
ARAM_000121Endo/exonuclease/phosphatase domain-containing protein. (606 aa)
ARAM_003142Fcf2 domain-containing protein. (197 aa)
ARAM_001031UV-damage endonuclease. (700 aa)
ARAM_006342Uncharacterized protein. (326 aa)
ARAM_005116Uncharacterized protein. (561 aa)
ARAM_007390Uncharacterized protein. (637 aa)
ARAM_004260Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (793 aa)
ARAM_00539940S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability. (88 aa)
ARAM_000440Exosome complex subunit Csl4. (245 aa)
ARAM_007201RNase_PH domain-containing protein. (407 aa)
ARAM_0074583'-5' exonuclease domain-containing protein. (356 aa)
ARAM_000934Uncharacterized protein. (961 aa)
ARAM_000891Putative polyadenylation factor subunit CstF64. (294 aa)
ARAM_005525Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1477 aa)
ARAM_000838Putative TFIIH complex helicase Ssl2. (822 aa)
ARAM_0008505'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1408 aa)
ARAM_001664KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (338 aa)
ARAM_007452Uncharacterized protein. (714 aa)
ARAM_006844SAP30_Sin3_bdg domain-containing protein. (234 aa)
ARAM_005453Helicase ATP-binding domain-containing protein. (791 aa)
ARAM_006209Putative exosome complex exonuclease Rrp40. (273 aa)
ARAM_002794tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (469 aa)
ARAM_000735RNase III domain-containing protein. (332 aa)
ARAM_000509Uncharacterized protein. (844 aa)
ARAM_006901Uncharacterized protein. (225 aa)
ARAM_001860Exonuclease domain-containing protein. (649 aa)
ARAM_006654Uncharacterized protein. (279 aa)
ARAM_004188DNA repair protein. (77 aa)
ARAM_004187Uncharacterized protein. (388 aa)
ARAM_001215Ribosome biogenesis protein. (363 aa)
ARAM_004298rRNA processing protein. (331 aa)
ARAM_007727Putative transcription factor. (746 aa)
ARAM_004053SAP domain-containing protein. (418 aa)
ARAM_005434Nop domain-containing protein. (584 aa)
ARAM_004583Putative mRNA cleavage and polyadenylation specificity factor complex subunit. (255 aa)
ARAM_004036Mitochondrial 54S ribosomal protein. (381 aa)
ARAM_004649Serine/threonine-protein phosphatase. (282 aa)
ARAM_000330rRNA processing protein. (624 aa)
ARAM_004855Ribonuclease T2; Belongs to the RNase T2 family. (263 aa)
ARAM_001387Uncharacterized protein. (512 aa)
USB1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (457 aa)
ARAM_005804RNase_PH domain-containing protein. (276 aa)
ARAM_004671Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1414 aa)
ARAM_005697Uncharacterized protein. (362 aa)
ARAM_007625Exosome component 3'-5' exonuclease. (787 aa)
ARAM_005129Putative exosome complex subunit Rrp46. (249 aa)
ARAM_002000Ribonuclease P protein subunit. (305 aa)
ARAM_003515Uncharacterized protein. (286 aa)
ARAM_006661DNA repair protein. (1001 aa)
ARAM_000841Nudix hydrolase domain-containing protein. (386 aa)
ARAM_004218CID domain-containing protein. (640 aa)
ARAM_005511Uncharacterized protein. (234 aa)
ARAM_006421Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (279 aa)
ARAM_000773Uncharacterized protein. (374 aa)
ARAM_005545Uncharacterized protein. (824 aa)
ARAM_006416Ribosome biogenesis protein. (594 aa)
ARAM_002850Uncharacterized protein. (88 aa)
ARAM_003433WD_REPEATS_REGION domain-containing protein. (534 aa)
ARAM_005367TNase-like domain-containing protein. (303 aa)
ARAM_006438Uncharacterized protein. (763 aa)
ARAM_001967Uncharacterized protein. (628 aa)
ARAM_000111Uncharacterized protein. (248 aa)
ARAM_006832Uncharacterized protein. (198 aa)
ARAM_006400XPG_I_2 domain-containing protein. (633 aa)
ARAM_000690Deoxyribonuclease Tat-D. (324 aa)
ARAM_006697Putative exosome complex endonuclease 2. (324 aa)
ARAM_005206Uncharacterized protein. (404 aa)
ARAM_002195Uncharacterized protein. (636 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1165 aa)
ARAM_000478Piwi domain-containing protein. (1069 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
ARAM_006461Uncharacterized protein. (957 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (406 aa)
ARAM_003840Uncharacterized protein. (1091 aa)
ARAM_0046945'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1029 aa)
ARAM_000385Uncharacterized protein. (1491 aa)
ARAM_000376Putative ribonuclease H. (403 aa)
ARAM_002368Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (820 aa)
ARAM_007082Uncharacterized protein. (531 aa)
ARAM_001283Uncharacterized protein. (783 aa)
ARAM_004388Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (357 aa)
ARAM_001405DNA polymerase. (1100 aa)
ARAM_004781Putative cleavage and polyadenylation specifity factor, 73 kDa subunit. (874 aa)
ARAM_001643rRNA-processing protein. (190 aa)
ARAM_005444Ribosome biogenesis protein. (1190 aa)
ARAM_004366Uncharacterized protein. (520 aa)
ARAM_005873Uncharacterized protein. (1816 aa)
ARAM_000168Uncharacterized protein. (388 aa)
ARAM_000167Uncharacterized protein. (1655 aa)
ARAM_000326WD_REPEATS_REGION domain-containing protein. (977 aa)
ARAM_003825DNA repair protein. (370 aa)
ARAM_005091Uncharacterized protein. (276 aa)
ARAM_005222KH domain-containing protein. (258 aa)
ARAM_002891Uncharacterized protein; Belongs to the RNase T2 family. (439 aa)
ARAM_005894Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (350 aa)
ARAM_002150XPGI domain-containing protein. (761 aa)
ARAM_002363Exosome complex component rrp4. (385 aa)
ARAM_007389Small nucleolar ribonucleoprotein. (902 aa)
ARAM_007250DNA-directed RNA polymerase III subunit RPC10. (96 aa)
ARAM_003847Uncharacterized protein. (149 aa)
ARAM_000492Ribosome biogenesis protein. (551 aa)
ARAM_000247Uncharacterized protein. (1170 aa)
ARAM_001242Uncharacterized protein. (495 aa)
ARAM_002341DBR1 domain-containing protein. (716 aa)
ARAM_002620Deoxyribonuclease Tat-D. (315 aa)
ARAM_003795DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (128 aa)
ARAM_004999Putative ribonuclease P complex subunit Pop1. (901 aa)
ARAM_002333Uncharacterized protein. (218 aa)
ARAM_003126RAI1 domain-containing protein. (378 aa)
ARAM_002308Ribosomal_L7Ae domain-containing protein. (225 aa)
ARAM_005377POLAc domain-containing protein. (1129 aa)
ARAM_00279220S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (431 aa)
ARAM_001795mRNA cleavage and polyadenylation specificity factor complex subunit. (763 aa)
ARAM_005171RNase III domain-containing protein. (266 aa)
ARAM_003234Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (220 aa)
ARAM_004031Cell wall biogenesis protein. (1381 aa)
ARAM_001214F-box domain protein. (358 aa)
ARAM_004303WD_REPEATS_REGION domain-containing protein. (946 aa)
ARAM_001867NACHT domain-containing protein. (1326 aa)
ARAM_0049623' exoribonuclease family protein. (376 aa)
ARAM_001999tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (309 aa)
ARAM_001979Uncharacterized protein. (1118 aa)
ARAM_006029RNase H domain-containing protein. (170 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (419 aa)
ARAM_003213RNB domain-containing protein. (1017 aa)
ARAM_005298Endonuclease. (335 aa)
ARAM_004317Calcium/calmodulin dependent protein. (130 aa)
ARAM_003981Cleavage and polyadenylation specificity factor subunit 2. (1012 aa)
ARAM_004661Putative CCR4-NOT core complex subunit Caf1. (489 aa)
ARAM_002800TP6A_N domain-containing protein. (383 aa)
ARAM_001436Exonuclease domain-containing protein. (942 aa)
ARAM_001765Uncharacterized protein. (439 aa)
ARAM_002776DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2231 aa)
ARAM_006561Putative exonuclease. (743 aa)
ARAM_001344Nudix hydrolase domain-containing protein. (818 aa)
ARAM_003432Bms1-type G domain-containing protein. (805 aa)
ARAM_005152Uncharacterized protein. (308 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (827 aa)
Your Current Organism:
Aspergillus rambellii
NCBI taxonomy Id: 308745
Other names: A. rambellii, ATCC 42001, CBS 101887, IBT 14580
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