(32 nodes) Coated vesicle membrane network (Aspergillus rambellii)

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	ARAM_005733	SNARE complex subunit SEC22; Belongs to the synaptobrevin family. (215 aa)
	ARAM_005566	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa)
	ARAM_005721	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (717 aa)
	ARAM_004009	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (746 aa)
	ARAM_007750	AP-2 complex subunit alpha. (150 aa)
	ARAM_003240	Putative Coatomer subunit epsilon. (162 aa)
	ARAM_006465	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (858 aa)
	ARAM_005125	BHLH domain-containing protein. (1025 aa)
	ARAM_004730	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (917 aa)
	ARAM_000821	Uncharacterized protein. (884 aa)
	ARAM_004746	DUF5353 domain-containing protein. (382 aa)
	ARAM_007074	EH domain binding protein. (543 aa)
	ARAM_006763	Uncharacterized protein. (199 aa)
	ARAM_004508	AP-1 complex subunit gamma. (845 aa)
	ARAM_001292	Rad60-SLD_2 domain-containing protein. (251 aa)
	ARAM_002575	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (237 aa)
	ARAM_000045	Arf-GAP domain-containing protein. (486 aa)
	ARAM_004693	Intracellular protein. (1029 aa)
	ARAM_005394	ENTH domain-containing protein. (536 aa)
	ARAM_006758	Uncharacterized protein. (409 aa)
	VMA21	Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (109 aa)
	ARAM_002756	Coatomer subunit beta. (974 aa)
	ARAM_006501	WD_REPEATS_REGION domain-containing protein. (1261 aa)
	ARAM_004012	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1214 aa)
	ARAM_004650	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (889 aa)
	ARAM_005364	Uncharacterized protein; Belongs to the universal ribosomal protein uL11 family. (935 aa)
	ARAM_005746	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (504 aa)
	ARAM_003979	Uncharacterized protein. (1013 aa)
	ARAM_000326	WD_REPEATS_REGION domain-containing protein. (977 aa)
	ARAM_005418	Putative AP-2 adaptor complex subunit alpha. (789 aa)
	ARAM_005614	Fibronectin type III domain protein. (1094 aa)
	ARAM_007596	Coatomer subunit epsilon. (134 aa)

Your Current Organism:

Aspergillus rambellii

NCBI taxonomy Id: 308745
Other names: A. rambellii, ATCC 42001, CBS 101887, IBT 14580

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARAM_000045	ARAM_002756	A0A0F8XC26	A0A0F8X0Q3	Arf-GAP domain-containing protein.	Coatomer subunit beta.	0.977
ARAM_000045	ARAM_003240	A0A0F8XC26	A0A0F8URP0	Arf-GAP domain-containing protein.	Putative Coatomer subunit epsilon.	0.703
ARAM_000045	ARAM_004012	A0A0F8XC26	A0A0F8WFX3	Arf-GAP domain-containing protein.	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	0.961
ARAM_000045	ARAM_004693	A0A0F8XC26	A0A0F8XAW0	Arf-GAP domain-containing protein.	Intracellular protein.	0.702
ARAM_000045	ARAM_004730	A0A0F8XC26	A0A0F8UPP6	Arf-GAP domain-containing protein.	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.977
ARAM_000045	ARAM_004746	A0A0F8XC26	A0A0F8U9I6	Arf-GAP domain-containing protein.	DUF5353 domain-containing protein.	0.595
ARAM_000045	ARAM_005566	A0A0F8XC26	A0A0F8V433	Arf-GAP domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.528
ARAM_000045	ARAM_005733	A0A0F8XC26	A0A0F8V570	Arf-GAP domain-containing protein.	SNARE complex subunit SEC22; Belongs to the synaptobrevin family.	0.867
ARAM_000045	ARAM_005746	A0A0F8XC26	A0A0F8VKV4	Arf-GAP domain-containing protein.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.948
ARAM_000045	ARAM_006465	A0A0F8XC26	A0A0F8URB7	Arf-GAP domain-containing protein.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.977
ARAM_000045	ARAM_007596	A0A0F8XC26	A0A0F8V5E1	Arf-GAP domain-containing protein.	Coatomer subunit epsilon.	0.703
ARAM_000821	ARAM_002756	A0A0F8UKK7	A0A0F8X0Q3	Uncharacterized protein.	Coatomer subunit beta.	0.501
ARAM_000821	ARAM_003979	A0A0F8UKK7	A0A0F8VDS3	Uncharacterized protein.	Uncharacterized protein.	0.999
ARAM_000821	ARAM_004012	A0A0F8UKK7	A0A0F8WFX3	Uncharacterized protein.	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	0.511
ARAM_000821	ARAM_004650	A0A0F8UKK7	A0A0F8W206	Uncharacterized protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.976
ARAM_000821	ARAM_004693	A0A0F8UKK7	A0A0F8XAW0	Uncharacterized protein.	Intracellular protein.	0.830
ARAM_000821	ARAM_004730	A0A0F8UKK7	A0A0F8UPP6	Uncharacterized protein.	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.472
ARAM_000821	ARAM_004746	A0A0F8UKK7	A0A0F8U9I6	Uncharacterized protein.	DUF5353 domain-containing protein.	0.784
ARAM_000821	ARAM_005364	A0A0F8UKK7	A0A0F8VLI8	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uL11 family.	0.999
ARAM_000821	ARAM_005733	A0A0F8UKK7	A0A0F8V570	Uncharacterized protein.	SNARE complex subunit SEC22; Belongs to the synaptobrevin family.	0.998