Groups of genes that are frequently observed in each other's genomic neighborhood.
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Experiments
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARAM_007465
SEC7 domain-containing protein. (1347 aa)
ARAM_006220
Uncharacterized protein. (1439 aa)
ARAM_004748
SEC7 domain-containing protein. (1993 aa)
ARAM_006487
Uncharacterized protein. (1400 aa)
Your Current Organism:
Aspergillus rambellii
NCBI taxonomy Id: 308745 Other names: A. rambellii, ATCC 42001, CBS 101887, IBT 14580