(71 nodes) Lysine degradation network (Aspergillus rambellii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARAM_003358	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (474 aa)
	ARAM_000233	Uncharacterized protein. (486 aa)
	ARAM_000671	Lipoyl-binding domain-containing protein. (467 aa)
	ARAM_002872	Uncharacterized protein. (327 aa)
	ARAM_006880	Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (497 aa)
	ARAM_007512	Extracellular developmental signal biosynthesis protein; Belongs to the glutamine synthetase family. (1386 aa)
	ARAM_006367	Putative acetyl-CoA-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (418 aa)
	ARAM_007006	Uncharacterized protein. (475 aa)
	ARAM_005169	Aldehyde dehydrogenase ALDH; Belongs to the aldehyde dehydrogenase family. (480 aa)
	ARAM_006597	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1212 aa)
	ARAM_006805	Isochorismatase domain-containing protein. (183 aa)
	ARAM_005317	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (345 aa)
	ARAM_004587	Uncharacterized protein. (523 aa)
	ARAM_002905	Zn(2)-C6 fungal-type domain-containing protein. (709 aa)
	ARAM_004037	Uncharacterized protein. (306 aa)
	ARAM_003797	SET domain protein. (630 aa)
	ARAM_000618	PHD-type domain-containing protein. (763 aa)
	ARAM_006120	Putative transcriptional regulator (Cti6). (618 aa)
	ARAM_007509	Uncharacterized protein. (331 aa)
	ARAM_002403	Succinate-semialdehyde dehydrogenase. (495 aa)
	ARAM_007214	Uncharacterized protein. (374 aa)
	ARAM_006169	Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (501 aa)
	ARAM_004474	Protein kinase domain-containing protein. (903 aa)
	ARAM_001324	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (508 aa)
	ARAM_004800	Chromosome condensation protein. (453 aa)
	ARAM_007323	Uncharacterized protein. (340 aa)
	ARAM_003422	Uncharacterized protein. (797 aa)
	ARAM_005958	MHYT domain-containing protein. (781 aa)
	ARAM_004848	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (621 aa)
	ARAM_003345	Succinate-semialdehyde dehydrogenase. (536 aa)
	ARAM_002529	Uncharacterized protein. (404 aa)
	ARAM_000259	Enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (289 aa)
	ARAM_000022	Uncharacterized protein. (537 aa)
	ARAM_007460	Zn(2)-C6 fungal-type domain-containing protein. (648 aa)
	ARAM_005614	Fibronectin type III domain protein. (1094 aa)
	ARAM_007324	PHD finger and SET domain protein. (555 aa)
	ARAM_005120	Uncharacterized protein. (560 aa)
	ARAM_004261	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
	ARAM_002278	Uncharacterized protein. (282 aa)
	ARAM_002270	Acetyl-CoA acetyltransferase IA; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
	ARAM_007579	Aldedh domain-containing protein. (157 aa)
	ARAM_002804	Uncharacterized protein. (248 aa)
	ARAM_000399	Uncharacterized protein. (828 aa)
	ARAM_002917	F-box domain protein. (549 aa)
	ARAM_002423	Putative C6 transcription factor. (830 aa)
	ARAM_002729	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (372 aa)
	ARAM_007602	Uncharacterized protein. (462 aa)
	ARAM_001749	Uncharacterized protein. (723 aa)
	ARAM_004321	Uncharacterized protein. (210 aa)
	ARAM_007162	Uncharacterized protein. (187 aa)
	ARAM_006214	TauD domain-containing protein. (488 aa)
	ARAM_007626	Uncharacterized protein. (274 aa)
	ARAM_001780	DAO domain-containing protein. (455 aa)
	ARAM_006372	Uncharacterized protein. (185 aa)
	ARAM_005685	Saccharopine dehydrogenase Lys9. (846 aa)
	ARAM_005648	Uncharacterized protein. (1036 aa)
	ARAM_007317	Uncharacterized protein. (191 aa)
	ARAM_003404	Zn(2)-C6 fungal-type domain-containing protein. (546 aa)
	ARAM_004484	Putative 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (250 aa)
	ARAM_001631	Dihydrolipoyl dehydrogenase. (514 aa)
	ARAM_001900	HTH myb-type domain-containing protein. (847 aa)
	ARAM_001501	Uncharacterized protein. (241 aa)
	ARAM_001487	Putative l-psp endoribonuclease family protein. (148 aa)
	ARAM_003354	AB hydrolase-1 domain-containing protein. (528 aa)
	ARAM_001575	Aldedh domain-containing protein. (109 aa)
	ARAM_001261	Uncharacterized protein. (395 aa)
	ARAM_005233	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (971 aa)
	ARAM_004716	DUF4470 domain-containing protein. (493 aa)
	ARAM_002060	Uncharacterized protein. (177 aa)
	ARAM_000364	Fungal_trans domain-containing protein. (469 aa)
	ARAM_001225	TauD domain-containing protein. (404 aa)

Your Current Organism:

Aspergillus rambellii

NCBI taxonomy Id: 308745
Other names: A. rambellii, ATCC 42001, CBS 101887, IBT 14580

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARAM_000022	ARAM_000399	A0A0F8V5K8	A0A0F8WF27	Uncharacterized protein.	Uncharacterized protein.	0.889
ARAM_000022	ARAM_000618	A0A0F8V5K8	A0A0F8UMX3	Uncharacterized protein.	PHD-type domain-containing protein.	0.421
ARAM_000022	ARAM_001324	A0A0F8V5K8	A0A0F8UVN7	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.929
ARAM_000022	ARAM_003422	A0A0F8V5K8	A0A0F8UWS4	Uncharacterized protein.	Uncharacterized protein.	0.556
ARAM_000022	ARAM_003797	A0A0F8V5K8	A0A0F8UM16	Uncharacterized protein.	SET domain protein.	0.888
ARAM_000022	ARAM_005233	A0A0F8V5K8	A0A0F8XDY4	Uncharacterized protein.	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.905
ARAM_000022	ARAM_006120	A0A0F8V5K8	A0A0F8UNX6	Uncharacterized protein.	Putative transcriptional regulator (Cti6).	0.421
ARAM_000022	ARAM_006597	A0A0F8V5K8	A0A0F8UGJ6	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.940
ARAM_000022	ARAM_007323	A0A0F8V5K8	A0A0F8UW66	Uncharacterized protein.	Uncharacterized protein.	0.602
ARAM_000022	ARAM_007324	A0A0F8V5K8	A0A0F8VKX0	Uncharacterized protein.	PHD finger and SET domain protein.	0.602
ARAM_000022	ARAM_007602	A0A0F8V5K8	A0A0F8WQV2	Uncharacterized protein.	Uncharacterized protein.	0.881
ARAM_000233	ARAM_000259	A0A0F8U2L6	A0A0F8V3W5	Uncharacterized protein.	Enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.411
ARAM_000233	ARAM_000671	A0A0F8U2L6	A0A0F8U7X5	Uncharacterized protein.	Lipoyl-binding domain-containing protein.	0.462
ARAM_000233	ARAM_001631	A0A0F8U2L6	A0A0F8X452	Uncharacterized protein.	Dihydrolipoyl dehydrogenase.	0.454
ARAM_000233	ARAM_001749	A0A0F8U2L6	A0A0F8WRD4	Uncharacterized protein.	Uncharacterized protein.	0.438
ARAM_000233	ARAM_002270	A0A0F8U2L6	A0A0F8W419	Uncharacterized protein.	Acetyl-CoA acetyltransferase IA; Belongs to the thiolase-like superfamily. Thiolase family.	0.438
ARAM_000233	ARAM_004484	A0A0F8U2L6	A0A0F8X1C9	Uncharacterized protein.	Putative 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	0.646
ARAM_000233	ARAM_004848	A0A0F8U2L6	A0A0F8V2F0	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.622
ARAM_000233	ARAM_006367	A0A0F8U2L6	A0A0F8UC41	Uncharacterized protein.	Putative acetyl-CoA-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.438
ARAM_000233	ARAM_006805	A0A0F8U2L6	A0A0F8UGR7	Uncharacterized protein.	Isochorismatase domain-containing protein.	0.462