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lysC | Aspartate kinase; Belongs to the aspartokinase family. (392 aa) | ||||
ltaE | Threonine aldolase. (341 aa) | ||||
ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (312 aa) | ||||
hom1 | Homoserine dehydrogenase. (317 aa) | ||||
ilvA1 | Threonine ammonia-lyase. (403 aa) | ||||
thrC1 | Threonine synthase. (367 aa) | ||||
hom2 | Homoserine dehydrogenase. (316 aa) | ||||
HVO_0608 | Oxidoreductase (homolog to zinc-containing alcohol dehydrogenase). (347 aa) | ||||
leuA1 | 2-isopropylmalate synthase / (R)-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (512 aa) | ||||
pabC | Aminodeoxychorismate lyase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (330 aa) | ||||
thrC2 | Threonine synthase. (389 aa) | ||||
dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. (288 aa) | ||||
lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (415 aa) | ||||
dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase. (280 aa) | ||||
dapB | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (253 aa) | ||||
dapA | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (305 aa) | ||||
leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (324 aa) | ||||
leuD1 | 3-isopropylmalate dehydratase small subunit. (202 aa) | ||||
leuC1 | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa) | ||||
HVO_1505 | Uncharacterized protein. (87 aa) | ||||
ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (348 aa) | ||||
ilvN | Acetolactate synthase small subunit. (218 aa) | ||||
ilvB1 | Acetolactate synthase large subunit. (587 aa) | ||||
leuA2 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (440 aa) | ||||
HVO_2114 | Homolog to 4-hydroxy-tetrahydrodipicolinate synthase. (311 aa) | ||||
thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (293 aa) | ||||
asd | Aspartate-semialdehyde dehydrogenase. (344 aa) | ||||
ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (584 aa) | ||||
thrC3 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (419 aa) |