(5 nodes) Proline biosynthesis, and FAD-linked oxidoreductase-like network (Salinibacter ruber)

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Your Input:
	SRU_0546	Proline dehydrogenase superfamily; Identified by match to protein family HMM PF01619. (286 aa)
	proB	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (376 aa)
	proA	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (436 aa)
	pruA	1-pyrroline-5-carboxylate dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236. (562 aa)
	proC	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa)

Your Current Organism:

Salinibacter ruber

NCBI taxonomy Id: 309807
Other names: S. ruber DSM 13855, Salinibacter ruber DSM 13855, Salinibacter ruber str. DSM 13855, Salinibacter ruber strain DSM 13855

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SRU_0546	proC	SRU_0546	SRU_1560	Proline dehydrogenase superfamily; Identified by match to protein family HMM PF01619.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.944
SRU_0546	pruA	SRU_0546	SRU_1517	Proline dehydrogenase superfamily; Identified by match to protein family HMM PF01619.	1-pyrroline-5-carboxylate dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236.	0.974
proA	proB	SRU_1253	SRU_1252	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.999
proA	proC	SRU_1253	SRU_1560	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.746
proA	pruA	SRU_1253	SRU_1517	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	1-pyrroline-5-carboxylate dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236.	0.906
proB	proA	SRU_1252	SRU_1253	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.999
proB	proC	SRU_1252	SRU_1560	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.922
proB	pruA	SRU_1252	SRU_1517	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	1-pyrroline-5-carboxylate dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236.	0.905
proC	SRU_0546	SRU_1560	SRU_0546	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	Proline dehydrogenase superfamily; Identified by match to protein family HMM PF01619.	0.944
proC	proA	SRU_1560	SRU_1253	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.746
proC	proB	SRU_1560	SRU_1252	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.922
proC	pruA	SRU_1560	SRU_1517	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	1-pyrroline-5-carboxylate dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236.	0.934
pruA	SRU_0546	SRU_1517	SRU_0546	1-pyrroline-5-carboxylate dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236.	Proline dehydrogenase superfamily; Identified by match to protein family HMM PF01619.	0.974
pruA	proA	SRU_1517	SRU_1253	1-pyrroline-5-carboxylate dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236.	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.906
pruA	proB	SRU_1517	SRU_1252	1-pyrroline-5-carboxylate dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236.	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.905
pruA	proC	SRU_1517	SRU_1560	1-pyrroline-5-carboxylate dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.934