| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SRU_1352 | SRU_1356 | SRU_1352 | SRU_1356 | Cyclase, putative; Identified by match to protein family HMM PF00753; match to protein family HMM TIGR01409. | Acetyltransferase, gnat family, putative; Identified by match to protein family HMM PF00583. | 0.526 |
| SRU_1352 | menA | SRU_1352 | SRU_1353 | Cyclase, putative; Identified by match to protein family HMM PF00753; match to protein family HMM TIGR01409. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.561 |
| SRU_1352 | menB | SRU_1352 | SRU_2766 | Cyclase, putative; Identified by match to protein family HMM PF00753; match to protein family HMM TIGR01409. | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. | 0.530 |
| SRU_1352 | menC | SRU_1352 | SRU_1354 | Cyclase, putative; Identified by match to protein family HMM PF00753; match to protein family HMM TIGR01409. | O-succinylbenzoic acid (OSB) synthetase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.540 |
| SRU_1352 | menD | SRU_1352 | SRU_1351 | Cyclase, putative; Identified by match to protein family HMM PF00753; match to protein family HMM TIGR01409. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | 0.596 |
| SRU_1352 | menE | SRU_1352 | SRU_1355 | Cyclase, putative; Identified by match to protein family HMM PF00753; match to protein family HMM TIGR01409. | O-succinylbenzoate-CoA ligase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923. | 0.808 |
| SRU_1352 | menF | SRU_1352 | SRU_1350 | Cyclase, putative; Identified by match to protein family HMM PF00753; match to protein family HMM TIGR01409. | Putative isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.592 |
| SRU_1352 | mqnA | SRU_1352 | SRU_1625 | Cyclase, putative; Identified by match to protein family HMM PF00753; match to protein family HMM TIGR01409. | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.596 |
| SRU_1356 | SRU_1352 | SRU_1356 | SRU_1352 | Acetyltransferase, gnat family, putative; Identified by match to protein family HMM PF00583. | Cyclase, putative; Identified by match to protein family HMM PF00753; match to protein family HMM TIGR01409. | 0.526 |
| SRU_1356 | menA | SRU_1356 | SRU_1353 | Acetyltransferase, gnat family, putative; Identified by match to protein family HMM PF00583. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.720 |
| SRU_1356 | menC | SRU_1356 | SRU_1354 | Acetyltransferase, gnat family, putative; Identified by match to protein family HMM PF00583. | O-succinylbenzoic acid (OSB) synthetase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.751 |
| SRU_1356 | menE | SRU_1356 | SRU_1355 | Acetyltransferase, gnat family, putative; Identified by match to protein family HMM PF00583. | O-succinylbenzoate-CoA ligase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923. | 0.786 |
| menA | SRU_1352 | SRU_1353 | SRU_1352 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Cyclase, putative; Identified by match to protein family HMM PF00753; match to protein family HMM TIGR01409. | 0.561 |
| menA | SRU_1356 | SRU_1353 | SRU_1356 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Acetyltransferase, gnat family, putative; Identified by match to protein family HMM PF00583. | 0.720 |
| menA | menB | SRU_1353 | SRU_2766 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. | 0.857 |
| menA | menC | SRU_1353 | SRU_1354 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | O-succinylbenzoic acid (OSB) synthetase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.906 |
| menA | menD | SRU_1353 | SRU_1351 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | 0.861 |
| menA | menE | SRU_1353 | SRU_1355 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | O-succinylbenzoate-CoA ligase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923. | 0.904 |
| menA | menF | SRU_1353 | SRU_1350 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Putative isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.661 |
| menA | ubiE | SRU_1353 | SRU_0824 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.919 |