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murQ murQ mutM mutM aroQ aroQ nnr nnr SRU_0509 SRU_0509 rfbB rfbB SRU_0737 SRU_0737 eno eno SRU_1012 SRU_1012 hemB hemB dapA dapA SRU_1328 SRU_1328 menC menC SRU_1435 SRU_1435 SRU_1447 SRU_1447 SRU_1477 SRU_1477 SRU_1508 SRU_1508 aroB aroB hemD hemD hisB hisB fumC fumC mqnA mqnA trpB trpB trpA trpA SRU_1841 SRU_1841 acnA acnA pheA pheA aroC aroC leuC leuC leuD leuD ilvD ilvD nth nth thrC thrC SRU_2793 SRU_2793
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
murQConserved hypothetical protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (311 aa)
mutMformamidopyrimidine-DNA glycosylase; Identified by similarity to SP:O34403; match to protein family HMM PF01149; match to protein family HMM PF06831. (265 aa)
aroQ3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (142 aa)
nnrPredicted sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity). In the N-terminal section; belongs to the NnrE/AIBP family. (542 aa)
SRU_0509Conserved hypothetical protein. (137 aa)
rfbBdTDP-glucose 4,6-dehydratase; Identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (342 aa)
SRU_0737Hypothetical protein; Identified by Glimmer2; putative. (379 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
SRU_1012Conserved hypothetical protein. (172 aa)
hemBDelta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. (340 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (302 aa)
SRU_1328Conserved hypothetical protein; Identified by similarity to GB:AAR35562.1. (389 aa)
menCO-succinylbenzoic acid (OSB) synthetase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (366 aa)
SRU_1435Putative dihydrodipicolinate synthase; Identified by match to protein family HMM PF00701. (312 aa)
SRU_1447Putative pterin-4-alpha-carbinolamine dehydratase; Identified by match to protein family HMM PF01329. (128 aa)
SRU_1477Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342. (658 aa)
SRU_1508Conserved hypothetical protein. (123 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (367 aa)
hemDuroporphyrinogen-III synthase; Identified by match to protein family HMM PF02602. (262 aa)
hisBImidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. (202 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (601 aa)
mqnAHypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (271 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (278 aa)
SRU_1841Conserved hypothetical protein TIGR00149; Identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149. (139 aa)
acnAAconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (910 aa)
pheAPrephenate dehydratase; Identified by match to protein family HMM PF00800; match to protein family HMM PF01842. (286 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (404 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (205 aa)
ilvDDihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family. (612 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (324 aa)
thrCThreonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260. (438 aa)
SRU_2793Putative 6-pyruvoyl tetrahydropterin synthase; Identified by match to protein family HMM PF01242. (137 aa)
Your Current Organism:
Salinibacter ruber
NCBI taxonomy Id: 309807
Other names: S. ruber DSM 13855, Salinibacter ruber DSM 13855, Salinibacter ruber str. DSM 13855, Salinibacter ruber strain DSM 13855
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