12 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pak1	Non-specific serine/threonine protein kinase. (562 aa)
	iqgap2	IQ motif containing GTPase activating protein 2. (1661 aa)
	nck2	Cytoplasmic protein. (396 aa)
	PAK3	Non-specific serine/threonine protein kinase. (575 aa)
	nck1	Cytoplasmic protein. (399 aa)
	pak2	Non-specific serine/threonine protein kinase. (528 aa)
	LOC101076479	Non-specific serine/threonine protein kinase. (722 aa)
	LOC101066462	Rho guanine nucleotide exchange factor (GEF) 7b. (851 aa)
	LOC101067723	Cell division cycle 42. (191 aa)
	LOC101068145	Uncharacterized protein. (191 aa)
	iqgap1	IQ motif containing GTPase activating protein 1. (1686 aa)
	rac2	Rac family small GTPase 2. (218 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101066462	LOC101067723	ENSTRUP00000069148	ENSTRUP00000078989	Rho guanine nucleotide exchange factor (GEF) 7b.	Cell division cycle 42.	0.671
LOC101066462	LOC101068145	ENSTRUP00000069148	ENSTRUP00000080891	Rho guanine nucleotide exchange factor (GEF) 7b.	Uncharacterized protein.	0.624
LOC101066462	LOC101076479	ENSTRUP00000069148	ENSTRUP00000064836	Rho guanine nucleotide exchange factor (GEF) 7b.	Non-specific serine/threonine protein kinase.	0.960
LOC101066462	PAK3	ENSTRUP00000069148	ENSTRUP00000042993	Rho guanine nucleotide exchange factor (GEF) 7b.	Non-specific serine/threonine protein kinase.	0.975
LOC101066462	nck1	ENSTRUP00000069148	ENSTRUP00000045455	Rho guanine nucleotide exchange factor (GEF) 7b.	Cytoplasmic protein.	0.602
LOC101066462	nck2	ENSTRUP00000069148	ENSTRUP00000034543	Rho guanine nucleotide exchange factor (GEF) 7b.	Cytoplasmic protein.	0.602
LOC101066462	pak1	ENSTRUP00000069148	ENSTRUP00000011910	Rho guanine nucleotide exchange factor (GEF) 7b.	Non-specific serine/threonine protein kinase.	0.975
LOC101066462	pak2	ENSTRUP00000069148	ENSTRUP00000063452	Rho guanine nucleotide exchange factor (GEF) 7b.	Non-specific serine/threonine protein kinase.	0.974
LOC101066462	rac2	ENSTRUP00000069148	ENSTRUP00000086987	Rho guanine nucleotide exchange factor (GEF) 7b.	Rac family small GTPase 2.	0.955
LOC101067723	LOC101066462	ENSTRUP00000078989	ENSTRUP00000069148	Cell division cycle 42.	Rho guanine nucleotide exchange factor (GEF) 7b.	0.671
LOC101067723	LOC101068145	ENSTRUP00000078989	ENSTRUP00000080891	Cell division cycle 42.	Uncharacterized protein.	0.900
LOC101067723	LOC101076479	ENSTRUP00000078989	ENSTRUP00000064836	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.970
LOC101067723	PAK3	ENSTRUP00000078989	ENSTRUP00000042993	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.986
LOC101067723	iqgap1	ENSTRUP00000078989	ENSTRUP00000086234	Cell division cycle 42.	IQ motif containing GTPase activating protein 1.	0.977
LOC101067723	iqgap2	ENSTRUP00000078989	ENSTRUP00000012578	Cell division cycle 42.	IQ motif containing GTPase activating protein 2.	0.977
LOC101067723	nck1	ENSTRUP00000078989	ENSTRUP00000045455	Cell division cycle 42.	Cytoplasmic protein.	0.595
LOC101067723	nck2	ENSTRUP00000078989	ENSTRUP00000034543	Cell division cycle 42.	Cytoplasmic protein.	0.595
LOC101067723	pak1	ENSTRUP00000078989	ENSTRUP00000011910	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.991
LOC101067723	pak2	ENSTRUP00000078989	ENSTRUP00000063452	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.982
LOC101067723	rac2	ENSTRUP00000078989	ENSTRUP00000086987	Cell division cycle 42.	Rac family small GTPase 2.	0.587