42 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tpr	Translocated promoter region b, nuclear basket protein. (2355 aa)
	eif4ebp3	Eukaryotic translation initiation factor 4E binding protein 3. (112 aa)
	LOC100144317	Uncharacterized protein; Belongs to the protein kinase superfamily. (537 aa)
	LOC100144316	Uncharacterized protein. (522 aa)
	LOC101062507	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (508 aa)
	LOC101079882	YTH N(6)-methyladenosine RNA binding protein 1. (593 aa)
	polr2d	Polymerase (RNA) II (DNA directed) polypeptide D. (142 aa)
	eif5	Eukaryotic translation initiation factor 5. (432 aa)
	gle1	GLE1 RNA export mediator. (717 aa)
	nck2	Cytoplasmic protein. (396 aa)
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1659 aa)
	IHABP	IHABP. (71 aa)
	mettl3	Methyltransferase like 3; Belongs to the MT-A70-like family. (582 aa)
	eif2ak1	Eukaryotic translation initiation factor 2-alpha kinase 1. (663 aa)
	lyve1	Eukaryotic translation initiation factor 4, gamma 2a. (1059 aa)
	nck1	Cytoplasmic protein. (399 aa)
	eif2s1	Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
	eif4ebp2	Eukaryotic translation initiation factor 4E binding protein 2. (114 aa)
	polr2g	Polymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
	dazl	Deleted in azoospermia-like. (227 aa)
	RPS6KB1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (531 aa)
	LOC101071696	Uncharacterized protein. (114 aa)
	LOC101065523	Protein phosphatase 1, regulatory subunit 15B. (380 aa)
	LOC101069052	RRM domain-containing protein. (260 aa)
	LOC101063094	PP1c_bdg domain-containing protein. (603 aa)
	ctif	CBP80/20-dependent translation initiation factor. (673 aa)
	LOC101063775	W2 domain-containing protein. (443 aa)
	alkbh1	AlkB homolog 1, histone H2A dioxygenase. (367 aa)
	DHX29	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1414 aa)
	uhmk1	U2AF homology motif (UHM) kinase 1. (480 aa)
	dnajc3	DnaJ (Hsp40) homolog, subfamily C, member 3a. (507 aa)
	ENSTRUP00000072037	annotation not available (72 aa)
	fmr1	Fragile X mental retardation 1. (604 aa)
	LOC101061949	DnaJ (Hsp40) homolog, subfamily C, member 3b. (546 aa)
	EIF3K	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (215 aa)
	LOC101079890	Uncharacterized protein. (119 aa)
	LOC101068829	Basic leucine zipper and W2 domains 1a. (424 aa)
	LOC101074350	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (518 aa)
	YTHDF1	YTH N6-methyladenosine RNA binding protein 1. (687 aa)
	impact	Impact RWD domain protein. (370 aa)
	ybx1	Y box binding protein 1. (325 aa)
	mif4gd	MIF4G domain containing a. (249 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHX29	eif5	ENSTRUP00000068521	ENSTRUP00000016220	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Eukaryotic translation initiation factor 5.	0.459
EIF2AK4	LOC100144316	ENSTRUP00000035789	ENSTRUP00000006486	Eukaryotic translation initiation factor 2 alpha kinase 4.	Uncharacterized protein.	0.949
EIF2AK4	LOC100144317	ENSTRUP00000035789	ENSTRUP00000006484	Eukaryotic translation initiation factor 2 alpha kinase 4.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.513
EIF2AK4	eif2ak1	ENSTRUP00000035789	ENSTRUP00000042969	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2-alpha kinase 1.	0.925
EIF2AK4	eif2s1	ENSTRUP00000035789	ENSTRUP00000046037	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.994
EIF2AK4	eif5	ENSTRUP00000035789	ENSTRUP00000016220	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 5.	0.707
EIF2AK4	impact	ENSTRUP00000035789	ENSTRUP00000082538	Eukaryotic translation initiation factor 2 alpha kinase 4.	Impact RWD domain protein.	0.468
EIF3K	eif2s1	ENSTRUP00000076579	ENSTRUP00000046037	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.962
EIF3K	eif5	ENSTRUP00000076579	ENSTRUP00000016220	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Eukaryotic translation initiation factor 5.	0.937
EIF3K	lyve1	ENSTRUP00000076579	ENSTRUP00000044746	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Eukaryotic translation initiation factor 4, gamma 2a.	0.696
IHABP	fmr1	ENSTRUP00000039039	ENSTRUP00000074215	IHABP.	Fragile X mental retardation 1.	0.460
LOC100144316	EIF2AK4	ENSTRUP00000006486	ENSTRUP00000035789	Uncharacterized protein.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.949
LOC100144316	LOC101061949	ENSTRUP00000006486	ENSTRUP00000076178	Uncharacterized protein.	DnaJ (Hsp40) homolog, subfamily C, member 3b.	0.445
LOC100144316	dnajc3	ENSTRUP00000006486	ENSTRUP00000070890	Uncharacterized protein.	DnaJ (Hsp40) homolog, subfamily C, member 3a.	0.507
LOC100144316	eif2ak1	ENSTRUP00000006486	ENSTRUP00000042969	Uncharacterized protein.	Eukaryotic translation initiation factor 2-alpha kinase 1.	0.954
LOC100144316	eif2s1	ENSTRUP00000006486	ENSTRUP00000046037	Uncharacterized protein.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.993
LOC100144317	EIF2AK4	ENSTRUP00000006484	ENSTRUP00000035789	Uncharacterized protein; Belongs to the protein kinase superfamily.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.513
LOC100144317	LOC101061949	ENSTRUP00000006484	ENSTRUP00000076178	Uncharacterized protein; Belongs to the protein kinase superfamily.	DnaJ (Hsp40) homolog, subfamily C, member 3b.	0.445
LOC100144317	dnajc3	ENSTRUP00000006484	ENSTRUP00000070890	Uncharacterized protein; Belongs to the protein kinase superfamily.	DnaJ (Hsp40) homolog, subfamily C, member 3a.	0.507
LOC100144317	eif2ak1	ENSTRUP00000006484	ENSTRUP00000042969	Uncharacterized protein; Belongs to the protein kinase superfamily.	Eukaryotic translation initiation factor 2-alpha kinase 1.	0.565