STRINGSTRING
nrp1 nrp1 LOC101075732 LOC101075732 LOC101067940 LOC101067940 LOC101070622 LOC101070622 capn7 capn7 LOC101066162 LOC101066162 rreb1 rreb1 LOC101076604 LOC101076604 fgfbp1 fgfbp1 plcg2 plcg2 LOC101075639 LOC101075639 TGFBR2 TGFBR2 cd40 cd40 rin2 rin2 mtor mtor LOC101071528 LOC101071528 zc3h12a zc3h12a agt agt pik3cg pik3cg vegfc vegfc LOC101074584 LOC101074584 LOC101064978 LOC101064978 adam17 adam17 mst1r mst1r sp1 sp1 LOC101067934 LOC101067934 tgf-beta1 tgf-beta1 plpp3 plpp3 nfe2l2 nfe2l2 sirt1 sirt1 bsg bsg sash1 sash1 ENSTRUP00000047861 ENSTRUP00000047861 pdgfb pdgfb LOC101077059 LOC101077059 GATA2 GATA2 LOC101067042 LOC101067042 atp5f1a atp5f1a LOC101066787 LOC101066787 LOC101068809 LOC101068809 fgf16 fgf16 LOC101072082 LOC101072082 ENSTRUP00000054486 ENSTRUP00000054486 LOC101076071 LOC101076071 vegfa vegfa itgb1bp1 itgb1bp1 LOC101065481 LOC101065481 LOC101069995 LOC101069995 met met atp5f1b atp5f1b LOC101076918 LOC101076918 hspb1 hspb1 ENSTRUP00000088182 ENSTRUP00000088182 LOC101066787-2 LOC101066787-2 fgf7 fgf7 LOC101061503 LOC101061503 LOC105417437 LOC105417437 plcg1 plcg1 TSTA3 TSTA3 ctsh ctsh bmpr2 bmpr2 glipr2 glipr2 lgmn lgmn LOC101061688 LOC101061688 aamp aamp LOC101071373 LOC101071373 igf2 igf2 H2S720_TAKRU H2S720_TAKRU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nrp1Neuropilin; Belongs to the neuropilin family. (955 aa)
LOC101075732Uncharacterized protein LOC101075732 isoform X1. (505 aa)
LOC101067940Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
LOC101070622Glucose-6-phosphate isomerase a. (445 aa)
capn7Calpain 7; Belongs to the peptidase C2 family. (828 aa)
LOC101066162acidPPc domain-containing protein. (314 aa)
rreb1Ras responsive element binding protein 1a. (1847 aa)
LOC101076604Tissue specific transplantation antigen P35B. (324 aa)
fgfbp1Fibroblast growth factor binding protein 1b. (207 aa)
plcg2Phosphoinositide phospholipase C. (1248 aa)
LOC101075639ADAM metallopeptidase domain 17b. (842 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
cd40CD40. (307 aa)
rin2Si:ch211-85n16.4. (877 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2554 aa)
LOC101071528Macrophage stimulating 1 receptor a. (1375 aa)
zc3h12aSi:dkey-206d17.12. (176 aa)
agtAngiotensinogen; Belongs to the serpin family. (422 aa)
pik3cgPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1127 aa)
vegfcVascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (421 aa)
LOC101074584Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
LOC101064978TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (577 aa)
adam17ADAM metallopeptidase domain 17a. (868 aa)
mst1rMacrophage stimulating 1 receptor b. (1374 aa)
sp1Sp1 transcription factor. (815 aa)
LOC101067934Uncharacterized protein. (210 aa)
tgf-beta1Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
plpp3Phospholipid phosphatase 3. (314 aa)
nfe2l2Nuclear factor, erythroid 2-like 2a. (604 aa)
sirt1Sirtuin 1. (689 aa)
bsgBasigin. (360 aa)
sash1SAM and SH3 domain containing 1a. (1350 aa)
ENSTRUP00000047861Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (193 aa)
pdgfbPlatelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (542 aa)
LOC101077059Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (327 aa)
GATA2GATA binding protein 2. (472 aa)
LOC101067042Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
atp5f1aATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (551 aa)
LOC101066787Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
LOC101068809ADP-ribosylation factor 6b; Belongs to the small GTPase superfamily. Arf family. (175 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
LOC101072082SAM and SH3 domain containing 1b. (846 aa)
ENSTRUP00000054486Uncharacterized protein. (1291 aa)
LOC101076071GATA binding protein 2a. (461 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (218 aa)
itgb1bp1Integrin beta 1 binding protein 1. (222 aa)
LOC1010654811-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like. (1307 aa)
LOC101069995Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
metUncharacterized protein. (1425 aa)
atp5f1bATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
LOC101076918RAB25, member RAS oncogene family b. (221 aa)
hspb1Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (200 aa)
ENSTRUP00000088182annotation not available (138 aa)
LOC101066787-2Transforming growth factor beta-2 proprotein. (413 aa)
fgf7Fibroblast growth factor 7; Belongs to the heparin-binding growth factors family. (238 aa)
LOC101061503Glucose-6-phosphate isomerase; Belongs to the GPI family. (591 aa)
LOC105417437SH2 domain-containing protein. (548 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1314 aa)
TSTA3Tissue specific transplantation antigen P35B. (351 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (350 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1065 aa)
glipr2GLI pathogenesis-related 2, like; Belongs to the CRISP family. (186 aa)
lgmnLegumain. (545 aa)
LOC101061688Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (618 aa)
aampAngio-associated, migratory cell protein. (453 aa)
LOC101071373Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
igf2Insulin-like growth factor 2b. (215 aa)
H2S720_TAKRUPI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (1038 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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