STRINGSTRING
kdm5a kdm5a LOC101062233 LOC101062233 LOC101064069 LOC101064069 phf2 phf2 phf8 phf8 LOC101062671 LOC101062671 pah pah LOC101075863 LOC101075863 LOC101070781 LOC101070781 LOC101072418 LOC101072418 LOC101065945 LOC101065945 coq6 coq6 LOC101071700 LOC101071700 plod2 plod2 LOC101061760 LOC101061760 ogfod3 ogfod3 LOC101063139 LOC101063139 LOC101067951 LOC101067951 msmo1 msmo1 ENSTRUP00000075715 ENSTRUP00000075715 cyp17a1 cyp17a1 fat-5 fat-5 mical3 mical3 degs2 degs2 LOC101063839 LOC101063839 pigs pigs PTGS1 PTGS1 LOC101074446 LOC101074446 LOC115246491 LOC115246491 LOC101066452 LOC101066452 ENSTRUP00000070940 ENSTRUP00000070940 pfcyp19a pfcyp19a ENSTRUP00000069616 ENSTRUP00000069616 LOC101062865 LOC101062865 ENSTRUP00000068563 ENSTRUP00000068563 alkbh1 alkbh1 ENSTRUP00000068326 ENSTRUP00000068326 th th pam pam LOC101072267 LOC101072267 plod1 plod1 alkbh2 alkbh2 LOC101061882 LOC101061882 LOC101074478 LOC101074478 kdm8 kdm8 Ccndbp1 Ccndbp1 tti2 tti2 mettl26 mettl26 ENSTRUP00000062089 ENSTRUP00000062089 LOC101075967 LOC101075967 ENSTRUP00000061623 ENSTRUP00000061623 hmox1 hmox1 kdm6a kdm6a ENSTRUP00000060342 ENSTRUP00000060342 nos1 nos1 LOC101065748 LOC101065748 ENSTRUP00000057270 ENSTRUP00000057270 LOC101062866-2 LOC101062866-2 jmjd4 jmjd4 LOC101078029 LOC101078029 ENSTRUP00000055943 ENSTRUP00000055943 egln3 egln3 alkbh3 alkbh3 LOC101074542 LOC101074542 LOC101072518-2 LOC101072518-2 LOC777946 LOC777946 LOC101068038 LOC101068038 ENSTRUP00000052097 ENSTRUP00000052097 p3h4 p3h4 hspbap1 hspbap1 LOC101077007 LOC101077007 ENSTRUP00000049967 ENSTRUP00000049967 hif1an hif1an KMO KMO LOC101065346 LOC101065346 asph asph fto fto LOC101072833 LOC101072833 ubiad1 ubiad1 tet2 tet2 LOC101065133 LOC101065133 LOC101062641 LOC101062641 LOC101075926 LOC101075926 H2VD05_TAKRU H2VD05_TAKRU LOC101075700 LOC101075700 LOC101077849 LOC101077849 LOC101077963 LOC101077963 fmo fmo ogfod1 ogfod1 LOC101079093 LOC101079093 LOC115247270 LOC115247270 p3h2 p3h2 LOC101071742 LOC101071742 LOC101074060 LOC101074060 LOC101063308 LOC101063308 LOC101062866 LOC101062866 ENSTRUP00000042272 ENSTRUP00000042272 bbox1 bbox1 LOC101064648 LOC101064648 LOC101073682 LOC101073682 kdm7a kdm7a LOC101073401 LOC101073401 LOC446095 LOC446095 crtap crtap kdm2a kdm2a H2UF66_TAKRU H2UF66_TAKRU LOC101063777 LOC101063777 alkbh5 alkbh5 LOC101069859 LOC101069859 LOC101077711 LOC101077711 LOC101072612 LOC101072612 LOC101071669 LOC101071669 tyrp1 tyrp1 LOC101076120 LOC101076120 sc5d sc5d kdm1a kdm1a LOC101075363 LOC101075363 coq7 coq7 LOC101069556 LOC101069556 cyp17a2 cyp17a2 p3h3 p3h3 LOC101075964 LOC101075964 P3H4 P3H4 LOC101065551 LOC101065551 LOC101065426 LOC101065426 LOC101080145 LOC101080145 dbh dbh tyw5 tyw5 LOC101080189 LOC101080189 LOC101074959 LOC101074959 LOC101079781 LOC101079781 tyr tyr agmo agmo ogfod2 ogfod2 tbxas1 tbxas1 tmem189 tmem189 dohh dohh LOC101073188 LOC101073188 LOC101069124 LOC101069124 hmox2 hmox2 alkbh8 alkbh8 LOC101069230 LOC101069230 LOC101072518 LOC101072518 tmlhe tmlhe dct dct LOC101068062 LOC101068062 LOC101063174 LOC101063174 LOC101071235 LOC101071235 LOC101061436 LOC101061436 LOC101067736 LOC101067736 LOC101079555 LOC101079555 ptgs2 ptgs2 LOC101069081 LOC101069081 p4ha1 p4ha1 KDM1B KDM1B tph2 tph2 LOC101063989 LOC101063989 p3h1 p3h1 CYP8B1 CYP8B1 LOC101075886 LOC101075886 jmjd6 jmjd6 CYP4F8 CYP4F8 JMJD8 JMJD8 LOC101076258 LOC101076258 p4ha2 p4ha2 LOC101069976 LOC101069976
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
kdm5aLysine (K)-specific demethylase 5A. (1754 aa)
LOC101062233Lysine (K)-specific demethylase 5Bb. (1545 aa)
LOC101064069Cytochrome P450, family 2, subfamily X, polypeptide 9; Belongs to the cytochrome P450 family. (487 aa)
phf2PHD finger protein 2. (1172 aa)
phf8PHD finger protein 8. (1023 aa)
LOC101062671Cytochrome P450, family 27, subfamily A, polypeptide 7; Belongs to the cytochrome P450 family. (537 aa)
pahUncharacterized protein. (478 aa)
LOC101075863Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (598 aa)
LOC101070781Prostaglandin-endoperoxide synthase 1. (592 aa)
LOC101072418Cholesterol 25-hydroxylase like 3. (358 aa)
LOC101065945Lysine (K)-specific demethylase 4B. (1207 aa)
coq6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (529 aa)
LOC101071700Fe2OG dioxygenase domain-containing protein. (576 aa)
plod2Fe2OG dioxygenase domain-containing protein. (767 aa)
LOC101061760Un-named hu7910. (717 aa)
ogfod3Urotensin-2 receptor 2. (371 aa)
LOC101063139Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (539 aa)
LOC101067951Uncharacterized protein; Belongs to the cytochrome P450 family. (483 aa)
msmo1Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (361 aa)
ENSTRUP00000075715Cytochrome P450, family 17, subfamily A, polypeptide 1. (522 aa)
cyp17a1Uncharacterized protein; Belongs to the cytochrome P450 family. (522 aa)
fat-5FA_desaturase domain-containing protein; Belongs to the fatty acid desaturase type 1 family. (371 aa)
mical3Microtubule associated monooxygenase, calponin and LIM domain containing 3a. (2062 aa)
degs2Delta(4)-desaturase, sphingolipid 2. (322 aa)
LOC101063839Cytochrome P450 2F2-like. (487 aa)
pigsPhosphatidylinositol glycan anchor biosynthesis, class S. (574 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (681 aa)
LOC101074446Cytochrome P450, family 4, subfamily T, polypeptide 8; Belongs to the cytochrome P450 family. (515 aa)
LOC115246491Cytidine monophospho-N-acetylneuraminic acid hydroxylase. (595 aa)
LOC101066452Uncharacterized protein; Belongs to the cytochrome P450 family. (518 aa)
ENSTRUP00000070940Cytidine monophospho-N-acetylneuraminic acid hydroxylase. (493 aa)
pfcyp19aUncharacterized protein; Belongs to the cytochrome P450 family. (533 aa)
ENSTRUP00000069616Transmembrane prolyl 4-hydroxylase-like. (439 aa)
LOC101062865Lysine (K)-specific demethylase 4A, genome duplicate a. (992 aa)
ENSTRUP00000068563annotation not available (96 aa)
alkbh1AlkB homolog 1, histone H2A dioxygenase. (367 aa)
ENSTRUP00000068326Egl-9 family hypoxia-inducible factor 1a. (307 aa)
thTyrosine 3-monooxygenase. (489 aa)
pamPeptidylglycine alpha-amidating monooxygenase. (1039 aa)
LOC101072267Monooxygenase, DBH-like 1, like. (95 aa)
plod1Fe2OG dioxygenase domain-containing protein. (744 aa)
alkbh2AlkB homolog 2, alpha-ketoglutarate-dependent dioxygenase. (245 aa)
LOC101061882Uncharacterized protein; Belongs to the cytochrome P450 family. (515 aa)
LOC101074478Uncharacterized protein; Belongs to the cytochrome P450 family. (545 aa)
kdm8Lysine (K)-specific demethylase 8. (517 aa)
Ccndbp1Cyclin-D1-binding protein 1 isoform X1. (342 aa)
tti2Uncharacterized protein. (507 aa)
mettl26Methyltransferase like 26. (206 aa)
ENSTRUP00000062089Cytochrome P450, family 1, subfamily C, polypeptide 2. (523 aa)
LOC101075967Dimethylaniline monooxygenase [N-oxide-forming]. (576 aa)
ENSTRUP00000061623annotation not available (485 aa)
hmox1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. (288 aa)
kdm6aLysine (K)-specific demethylase 6A, like. (1459 aa)
ENSTRUP00000060342annotation not available (374 aa)
nos1Nitric oxide synthase; Produces nitric oxide (NO). (1428 aa)
LOC101065748Lysine (K)-specific demethylase 6B, a. (2102 aa)
ENSTRUP00000057270annotation not available (96 aa)
LOC101062866-2Dimethylaniline monooxygenase [N-oxide-forming]. (556 aa)
jmjd4Jumonji domain containing 4. (431 aa)
LOC101078029Uncharacterized protein. (1706 aa)
ENSTRUP00000055943Uncharacterized protein; Belongs to the cytochrome P450 family. (514 aa)
egln3Egl-9 family hypoxia-inducible factor 3. (267 aa)
alkbh3AlkB homolog 3, alpha-ketoglutarate-dependent dioxygenase. (329 aa)
LOC101074542Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family. (521 aa)
LOC101072518-2Sphingolipid delta(4)-desaturase DES1-like. (323 aa)
LOC777946Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (333 aa)
LOC101068038Tet methylcytosine dioxygenase 3. (1910 aa)
ENSTRUP00000052097annotation not available (438 aa)
p3h4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (476 aa)
hspbap1Hspb associated protein 1. (435 aa)
LOC101077007Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. (309 aa)
ENSTRUP00000049967annotation not available (483 aa)
hif1anHypoxia inducible factor 1 subunit alpha inhibitor. (382 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (481 aa)
LOC101065346Tet methylcytosine dioxygenase 1. (2145 aa)
asphAsp-B-Hydro_N domain-containing protein. (594 aa)
ftoFTO alpha-ketoglutarate dependent dioxygenase. (635 aa)
LOC101072833Zgc:158254. (501 aa)
ubiad1UbiA prenyltransferase domain containing 1. (349 aa)
tet2Tet methylcytosine dioxygenase 2. (1770 aa)
LOC101065133Cholesterol 25-hydroxylase like 1, tandem duplicate 2; Belongs to the sterol desaturase family. (264 aa)
LOC101062641Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (583 aa)
LOC101075926Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family. (499 aa)
H2VD05_TAKRUCytochrome P450, family 2, subfamily AD, polypeptide 2; Belongs to the cytochrome P450 family. (497 aa)
LOC101075700Cytochrome P450, family 2, subfamily P, polypeptide 6; Belongs to the cytochrome P450 family. (498 aa)
LOC101077849Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family. (273 aa)
LOC101077963Cytochrome P450, family 24, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (515 aa)
fmoDimethylaniline monooxygenase [N-oxide-forming]. (537 aa)
ogfod12-oxoglutarate and iron-dependent oxygenase domain containing 1. (526 aa)
LOC101079093Uncharacterized protein; Belongs to the cytochrome P450 family. (537 aa)
LOC115247270Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family. (533 aa)
p3h2Prolyl 3-hydroxylase 2. (679 aa)
LOC101071742Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. (519 aa)
LOC101074060Cytochrome P450, family 27, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (539 aa)
LOC101063308Dimethylaniline monooxygenase [N-oxide-forming]. (556 aa)
LOC101062866Dimethylaniline monooxygenase [N-oxide-forming]. (561 aa)
ENSTRUP00000042272annotation not available (360 aa)
bbox1Butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1. (447 aa)
LOC101064648Uncharacterized protein; Belongs to the cytochrome P450 family. (504 aa)
LOC101073682Uncharacterized protein; Belongs to the cytochrome P450 family. (510 aa)
kdm7aLysine (K)-specific demethylase 7Ab. (769 aa)
LOC101073401Prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum). (488 aa)
LOC446095Tyrosine hydroxylase 2. (479 aa)
crtapCartilage associated protein. (405 aa)
kdm2aLysine (K)-specific demethylase 2Ab. (1285 aa)
H2UF66_TAKRUCytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (529 aa)
LOC101063777Si:dkey-91i10.3; Belongs to the cytochrome P450 family. (537 aa)
alkbh5AlkB homolog 5, RNA demethylase. (380 aa)
LOC101069859Lysine (K)-specific demethylase 5Ba. (1474 aa)
LOC101077711Serum amyloid A-like 1. (488 aa)
LOC101072612Cytochrome P450, family 26, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (522 aa)
LOC101071669Egl-9 family hypoxia-inducible factor 2. (572 aa)
tyrp1Tyrosinase related protein 1. (521 aa)
LOC101076120Cytochrome P450, family 26, subfamily b, polypeptide 1; Belongs to the cytochrome P450 family. (512 aa)
sc5dSterol-C5-desaturase; Belongs to the sterol desaturase family. (278 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (846 aa)
LOC101075363Zgc:103625. (215 aa)
coq75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (217 aa)
LOC101069556Cytochrome P450, family 7, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (513 aa)
cyp17a2Uncharacterized protein; Belongs to the cytochrome P450 family. (544 aa)
p3h3Prolyl 3-hydroxylase 3. (728 aa)
LOC101075964Lysine (K)-specific demethylase 2Bb. (1382 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (424 aa)
LOC101065551Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (457 aa)
LOC101065426Cytochrome P450, family 20, subfamily A, polypeptide 1. (463 aa)
LOC101080145Tyrosinase. (536 aa)
dbhDopamine beta-hydroxylase (dopamine beta-monooxygenase). (619 aa)
tyw5tRNA-yW synthesizing protein 5. (330 aa)
LOC101080189Uncharacterized protein. (501 aa)
LOC101074959Cytochrome P450, family 2, subfamily U, polypeptide 1; Belongs to the cytochrome P450 family. (522 aa)
LOC101079781Lysine (K)-specific demethylase 4A, genome duplicate b. (1139 aa)
tyrTyrosinase. (540 aa)
agmoAlkylglycerol monooxygenase; Belongs to the sterol desaturase family. (445 aa)
ogfod22-oxoglutarate and iron-dependent oxygenase domain containing 2. (350 aa)
tbxas1Thromboxane A synthase 1 (platelet); Belongs to the cytochrome P450 family. (549 aa)
tmem189Transmembrane protein 189. (275 aa)
dohhDeoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (304 aa)
LOC101073188Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (532 aa)
LOC101069124Uncharacterized protein; Belongs to the cytochrome P450 family. (521 aa)
hmox2Heme oxygenase 2b. (309 aa)
alkbh8AlkB homolog 8, tRNA methyltransferase. (708 aa)
LOC101069230Prostaglandin I2 (prostacyclin) synthase; Belongs to the cytochrome P450 family. (498 aa)
LOC101072518Delta(4)-desaturase, sphingolipid 1. (323 aa)
tmlheTrimethyllysine hydroxylase, epsilon. (434 aa)
dctDopachrome tautomerase. (516 aa)
LOC101068062Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1278 aa)
LOC101063174Lysine (K)-specific demethylase 2Aa. (1318 aa)
LOC101071235Lysine (K)-specific demethylase 2Ba. (780 aa)
LOC101061436Cytochrome P450, family 4, subfamily V, polypeptide 8; Belongs to the cytochrome P450 family. (516 aa)
LOC101067736Flavin-containing monooxygenase. (429 aa)
LOC101079555Lysine (K)-specific demethylase 4C. (1606 aa)
ptgs2Prostaglandin-endoperoxide synthase 2b. (617 aa)
LOC101069081Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (450 aa)
p4ha1Prolyl 4-hydroxylase, alpha polypeptide I b. (591 aa)
KDM1BLysine demethylase 1B. (834 aa)
tph2Uncharacterized protein. (502 aa)
LOC101063989Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (488 aa)
p3h1Prolyl 3-hydroxylase 1. (730 aa)
CYP8B1Uncharacterized protein; Belongs to the cytochrome P450 family. (552 aa)
LOC101075886Cytochrome P450, family 3, subfamily c, polypeptide 3; Belongs to the cytochrome P450 family. (498 aa)
jmjd6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (403 aa)
CYP4F8Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family. (501 aa)
JMJD8Jumonji domain containing 8. (264 aa)
LOC101076258Lysine (K)-specific demethylase 5C. (1603 aa)
p4ha2Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2. (558 aa)
LOC101069976Si:ch211-113j14.1; Belongs to the cytochrome P450 family. (531 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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