STRINGSTRING
mettl16 mettl16 cnot8 cnot8 mettl14 mettl14 patl1 patl1 dhx36 dhx36 exosc8 exosc8 tpr tpr eif4ebp3 eif4ebp3 LOC100144317 LOC100144317 LOC100144316 LOC100144316 Rc3h2 Rc3h2 dcp1a dcp1a LOC101071011 LOC101071011 rnf139 rnf139 exosc9 exosc9 LOC101079882 LOC101079882 LOC101070860 LOC101070860 polr2d polr2d LOC101074895 LOC101074895 pde12 pde12 PAN3 PAN3 SAMD4B SAMD4B dis3l2 dis3l2 eprs1 eprs1 cnot9 cnot9 LOC101076133 LOC101076133 ythdf3 ythdf3 exosc7 exosc7 rc3h1 rc3h1 hnrnpr hnrnpr exosc5 exosc5 rbm24 rbm24 LOC101071342 LOC101071342 MARF1 MARF1 zc3h12a zc3h12a Rida Rida LOC101068848 LOC101068848 ythdf2 ythdf2 caprin2 caprin2 trim71 trim71 H2UCW4_TAKRU H2UCW4_TAKRU EIF2AK4 EIF2AK4 pan2 pan2 LOC101072348 LOC101072348 LOC101078534 LOC101078534 Parn Parn EIF4ENIF1 EIF4ENIF1 mettl3 mettl3 cnot3 cnot3 LOC101065677 LOC101065677 LOC105417758 LOC105417758 pus7 pus7 cpeb1 cpeb1 eif2ak1 eif2ak1 cnot11 cnot11 eif2s1 eif2s1 mov10 mov10 eif4ebp2 eif4ebp2 dcps dcps patl2 patl2 Nanos3 Nanos3 LOC101067689 LOC101067689 zar1 zar1 samd4a samd4a fto fto ENSTRUP00000049508 ENSTRUP00000049508 syncrip syncrip LOC101065621 LOC101065621 LOC101075774 LOC101075774 LOC101068811 LOC101068811 LOC101064780 LOC101064780 LOC101071696 LOC101071696 ddx6 ddx6 LOC101070680 LOC101070680 ENSTRUP00000056992 ENSTRUP00000056992 LOC101072935 LOC101072935 LOC101066313 LOC101066313 LOC101068354 LOC101068354 LOC101078091 LOC101078091 LOC101077107 LOC101077107 fxr1 fxr1 cnot2 cnot2 LOC101061545 LOC101061545 LOC101067386 LOC101067386 lrrc27 lrrc27 ago3 ago3 LOC101069758 LOC101069758 cnot6l cnot6l plekhn1 plekhn1 DCPS DCPS LOC101069239 LOC101069239 LOC101079762 LOC101079762 CPEB4 CPEB4 LOC101069703 LOC101069703 LOC101062906 LOC101062906 Dcp2 Dcp2 ENSTRUP00000072037 ENSTRUP00000072037 cpeb3 cpeb3 shmt1 shmt1 rpl13a rpl13a fmr1 fmr1 cnot10 cnot10 exosc2 exosc2 ENSTRUP00000076169 ENSTRUP00000076169 LOC101079890 LOC101079890 tnrc6a tnrc6a srp9 srp9 LOC101067716 LOC101067716 LOC101067349 LOC101067349 LOC101065854 LOC101065854 zfp36l1 zfp36l1 YTHDF1 YTHDF1 cpeb2 cpeb2 TUT4 TUT4 xrn1 xrn1 zfp36l2 zfp36l2 PNPT1 PNPT1 ybx1 ybx1 SHMT2 SHMT2 H2V528_TAKRU H2V528_TAKRU
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
mettl16U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (559 aa)
cnot8CCR4-NOT transcription complex, subunit 8. (285 aa)
mettl14Methyltransferase like 14; Belongs to the MT-A70-like family. (455 aa)
patl1PAT1 homolog 1, processing body mRNA decay factor. (829 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1046 aa)
exosc8Exosome component 8. (276 aa)
tprTranslocated promoter region b, nuclear basket protein. (2355 aa)
eif4ebp3Eukaryotic translation initiation factor 4E binding protein 3. (112 aa)
LOC100144317Uncharacterized protein; Belongs to the protein kinase superfamily. (537 aa)
LOC100144316Uncharacterized protein. (522 aa)
Rc3h2Ring finger and CCCH-type domains 2. (1042 aa)
dcp1aDecapping mRNA 1A. (497 aa)
LOC101071011LSM14A mRNA processing body assembly factor a. (486 aa)
rnf139Ring finger protein 139. (702 aa)
exosc9Exosome component 9. (395 aa)
LOC101079882YTH N(6)-methyladenosine RNA binding protein 1. (593 aa)
LOC101070860TSC complex subunit 1b. (1291 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (142 aa)
LOC101074895Nocturnin. (449 aa)
pde12Phosphodiesterase 12. (590 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (839 aa)
SAMD4BSterile alpha motif domain containing 4B. (666 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1042 aa)
eprs1Glutamyl-prolyl-tRNA synthetase. (1578 aa)
cnot9CCR4-NOT transcription complex subunit 9. (297 aa)
LOC101076133CCR4-NOT transcription complex, subunit 3b. (1009 aa)
ythdf3YTH N(6)-methyladenosine RNA binding protein 3. (603 aa)
exosc7Exosome component 7. (292 aa)
rc3h1Ring finger and CCCH-type domains 1b. (1123 aa)
hnrnprHeterogeneous nuclear ribonucleoprotein R. (618 aa)
exosc5Exosome component 5. (219 aa)
rbm24RNA binding motif protein 24a. (232 aa)
LOC101071342Si:dkey-46g23.1. (1955 aa)
MARF1Meiosis regulator and mRNA stability factor 1. (1769 aa)
zc3h12aSi:dkey-206d17.12. (176 aa)
RidaReactive intermediate imine deaminase A homolog. (219 aa)
LOC101068848Cytoplasmic polyadenylation element binding protein 4a. (744 aa)
ythdf2YTH N(6)-methyladenosine RNA binding protein 2. (665 aa)
caprin2Caprin family member 2. (896 aa)
trim71Tripartite motif containing 71, E3 ubiquitin protein ligase. (840 aa)
H2UCW4_TAKRUTSC complex subunit 1. (389 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1659 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1209 aa)
LOC101072348Synaptotagmin binding, cytoplasmic RNA interacting protein. (633 aa)
LOC101078534RNA binding motif protein 24b. (290 aa)
ParnUncharacterized protein. (713 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (959 aa)
mettl3Methyltransferase like 3; Belongs to the MT-A70-like family. (582 aa)
cnot3CCR4-NOT transcription complex, subunit 3a. (900 aa)
LOC101065677LSM14A mRNA processing body assembly factor b. (415 aa)
LOC105417758Decapping mRNA 1B. (620 aa)
pus7Pseudouridine synthase 7. (667 aa)
cpeb1Cytoplasmic polyadenylation element binding protein 1b. (572 aa)
eif2ak1Eukaryotic translation initiation factor 2-alpha kinase 1. (663 aa)
cnot11CCR4-NOT transcription complex, subunit 11. (444 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
mov10Mov10 RISC complex RNA helicase a. (996 aa)
eif4ebp2Eukaryotic translation initiation factor 4E binding protein 2. (114 aa)
dcpsUncharacterized protein. (388 aa)
patl2PAT1 homolog 2. (704 aa)
Nanos3Nanos homolog 3. (203 aa)
LOC101067689Insulin-like growth factor binding protein 5a. (300 aa)
zar1Zygote arrest protein 1; Essential for female fertility. May play a role in the oocyte-to-embryo transition (By similarity); Belongs to the ZAR1 family. (320 aa)
samd4aSterile alpha motif domain containing 4A. (699 aa)
ftoFTO alpha-ketoglutarate dependent dioxygenase. (635 aa)
ENSTRUP00000049508Nanos-type domain-containing protein. (136 aa)
syncripSynaptotagmin binding, cytoplasmic RNA interacting protein, like. (578 aa)
LOC101065621Zgc:162730. (418 aa)
LOC101075774Sb:cb81. (398 aa)
LOC101068811Nanos-type domain-containing protein; Belongs to the nanos family. (220 aa)
LOC101064780CCR4-NOT transcription complex, subunit 7. (285 aa)
LOC101071696Uncharacterized protein. (114 aa)
ddx6DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family. (482 aa)
LOC101070680Uncharacterized protein; Belongs to the DEAD box helicase family. (489 aa)
ENSTRUP00000056992Nanos homolog 1; Belongs to the nanos family. (226 aa)
LOC101072935CCR4-NOT transcription complex, subunit 6a. (556 aa)
LOC101066313Exosome component 3. (250 aa)
LOC101068354TNRC6-PABC_bdg domain-containing protein. (2103 aa)
LOC101078091Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (881 aa)
LOC101077107Fragile X mental retardation, autosomal homolog 2. (683 aa)
fxr1Fragile X mental retardation, autosomal homolog 1. (686 aa)
cnot2CCR4-NOT transcription complex, subunit 2. (551 aa)
LOC101061545Insulin like growth factor binding protein 5. (265 aa)
LOC101067386Argonaute RISC catalytic component 3a; Belongs to the argonaute family. (872 aa)
lrrc27Leucine-rich repeat-containing protein 27. (416 aa)
ago3Uncharacterized protein; Belongs to the argonaute family. (884 aa)
LOC101069758Reactive intermediate imine deaminase A homolog. (160 aa)
cnot6lCCR4-NOT transcription complex, subunit 6-like. (558 aa)
plekhn1Pleckstrin homology domain containing, family N member 1. (696 aa)
DCPSDecapping enzyme, scavenger. (332 aa)
LOC101069239U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (151 aa)
LOC101079762Trinucleotide repeat containing adaptor 6C2. (1572 aa)
CPEB4Cytoplasmic polyadenylation element binding protein 4. (776 aa)
LOC101069703NOT2_3_5 domain-containing protein. (629 aa)
LOC101062906Argonaute RISC component 1; Belongs to the argonaute family. (882 aa)
Dcp2DCP2 domain-containing protein. (246 aa)
ENSTRUP00000072037annotation not available (72 aa)
cpeb3Cytoplasmic polyadenylation element binding protein 3. (669 aa)
shmt1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (516 aa)
rpl13aRibosomal protein L13a; Belongs to the universal ribosomal protein uL13 family. (228 aa)
fmr1Fragile X mental retardation 1. (604 aa)
cnot10CCR4-NOT transcription complex, subunit 10. (771 aa)
exosc2Exosome component 2. (296 aa)
ENSTRUP00000076169Uncharacterized protein. (733 aa)
LOC101079890Uncharacterized protein. (119 aa)
tnrc6aTrinucleotide repeat containing adaptor 6A. (1865 aa)
srp9Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. (86 aa)
LOC101067716Nocturnin. (399 aa)
LOC101067349Serine hydroxymethyltransferase 2 (mitochondrial). (527 aa)
LOC101065854Zgc:114130. (429 aa)
zfp36l1Zinc finger protein 36, C3H type-like 1a. (428 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (687 aa)
cpeb2Cytoplasmic polyadenylation element binding protein 2. (795 aa)
TUT4Uncharacterized protein. (1141 aa)
xrn15'-3' exoribonuclease 1. (1684 aa)
zfp36l2Zinc finger protein 36, C3H type-like 2. (432 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (797 aa)
ybx1Y box binding protein 1. (325 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (558 aa)
H2V528_TAKRUCaprin-1_dimer domain-containing protein. (601 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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