31 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ctr9	CTR9 homolog, Paf1/RNA polymerase II complex component. (1138 aa)
	LOC101065779	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (910 aa)
	cdc73	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (567 aa)
	med14	Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1448 aa)
	ENSTRUP00000052849	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (148 aa)
	Nanos3	Nanos homolog 3. (203 aa)
	ENSTRUP00000081256	T-cell acute lymphocytic leukemia protein 1. (186 aa)
	CDH2-2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (937 aa)
	LOC101075116	Lin-28 homolog A. (229 aa)
	trim8	Tripartite motif containing 8b. (590 aa)
	pcm1	Pericentriolar material 1 protein. (2076 aa)
	rif1	Replication timing regulatory factor 1. (2308 aa)
	mettl3	Methyltransferase like 3; Belongs to the MT-A70-like family. (582 aa)
	EIF4ENIF1	Eukaryotic translation initiation factor 4E nuclear import factor 1. (959 aa)
	LOC101070994	Failed axon connections homolog, metaxin like GST domain containing a. (409 aa)
	mcph1	Microcephalin 1. (841 aa)
	fancc	FA complementation group C. (594 aa)
	rtf1	RTF1 homolog, Paf1/RNA polymerase II complex component. (675 aa)
	prdm14	PR domain containing 14. (602 aa)
	lig4	DNA ligase. (908 aa)
	sall4	Spalt-like transcription factor 4. (1023 aa)
	smc3	Structural maintenance of chromosomes protein. (1162 aa)
	dis3l2	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1042 aa)
	vps72	Vacuolar protein sorting 72 homolog a. (365 aa)
	LOC101079556	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (179 aa)
	mettl14	Methyltransferase like 14; Belongs to the MT-A70-like family. (455 aa)
	fezf2	FEZ family zinc finger 2. (422 aa)
	faxc	Failed axon connections homolog, metaxin like GST domain containing b. (415 aa)
	LOC101069239	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (151 aa)
	CDH2	Cadherin 2. (925 aa)
	LOC101065935	T-cell acute lymphocytic leukemia protein 1; Transcription factor that plays a pivotal role in hemopoietic and endothelial development. (405 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2-2	LOC101065779	ENSTRUP00000067097	ENSTRUP00000066251	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.901
EIF4ENIF1	LOC101069239	ENSTRUP00000039094	ENSTRUP00000065009	Eukaryotic translation initiation factor 4E nuclear import factor 1.	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	0.415
EIF4ENIF1	rtf1	ENSTRUP00000039094	ENSTRUP00000031453	Eukaryotic translation initiation factor 4E nuclear import factor 1.	RTF1 homolog, Paf1/RNA polymerase II complex component.	0.542
EIF4ENIF1	vps72	ENSTRUP00000039094	ENSTRUP00000014805	Eukaryotic translation initiation factor 4E nuclear import factor 1.	Vacuolar protein sorting 72 homolog a.	0.448
LOC101065779	CDH2-2	ENSTRUP00000066251	ENSTRUP00000067097	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.901
LOC101069239	EIF4ENIF1	ENSTRUP00000065009	ENSTRUP00000039094	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Eukaryotic translation initiation factor 4E nuclear import factor 1.	0.415
LOC101069239	ctr9	ENSTRUP00000065009	ENSTRUP00000075616	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.548
LOC101069239	dis3l2	ENSTRUP00000065009	ENSTRUP00000015436	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	0.409
LOC101069239	rtf1	ENSTRUP00000065009	ENSTRUP00000031453	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	RTF1 homolog, Paf1/RNA polymerase II complex component.	0.569
LOC101075116	dis3l2	ENSTRUP00000067644	ENSTRUP00000015436	Lin-28 homolog A.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	0.446
LOC101075116	prdm14	ENSTRUP00000067644	ENSTRUP00000029690	Lin-28 homolog A.	PR domain containing 14.	0.649
LOC101075116	sall4	ENSTRUP00000067644	ENSTRUP00000018309	Lin-28 homolog A.	Spalt-like transcription factor 4.	0.612
cdc73	ctr9	ENSTRUP00000054471	ENSTRUP00000075616	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae).	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.999
cdc73	rtf1	ENSTRUP00000054471	ENSTRUP00000031453	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae).	RTF1 homolog, Paf1/RNA polymerase II complex component.	0.994
cdc73	vps72	ENSTRUP00000054471	ENSTRUP00000014805	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae).	Vacuolar protein sorting 72 homolog a.	0.550
ctr9	LOC101069239	ENSTRUP00000075616	ENSTRUP00000065009	CTR9 homolog, Paf1/RNA polymerase II complex component.	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	0.548
ctr9	cdc73	ENSTRUP00000075616	ENSTRUP00000054471	CTR9 homolog, Paf1/RNA polymerase II complex component.	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae).	0.999
ctr9	rtf1	ENSTRUP00000075616	ENSTRUP00000031453	CTR9 homolog, Paf1/RNA polymerase II complex component.	RTF1 homolog, Paf1/RNA polymerase II complex component.	0.994
dis3l2	LOC101069239	ENSTRUP00000015436	ENSTRUP00000065009	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	0.409
dis3l2	LOC101075116	ENSTRUP00000015436	ENSTRUP00000067644	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Lin-28 homolog A.	0.446