(12 nodes) Cholesterol efflux network (Takifugu rubripes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	spg11	Spatacsin_C domain-containing protein. (2378 aa)
	npc2	Niemann-Pick disease, type C2. (151 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (512 aa)
	abcg8	ATP-binding cassette, sub-family G (WHITE), member 8. (659 aa)
	apoe2	Apolipoprotein E2. (276 aa)
	ENSTRUP00000074430	annotation not available (262 aa)
	ENSTRUP00000084559	ATP-binding cassette, subfamily G (WHITE), member 1. (666 aa)
	abcg4	ATP-binding cassette, sub-family G (WHITE), member 4a. (643 aa)
	LOC101066818	Apolipoprotein Bb, tandem duplicate 2. (3788 aa)
	H2RM54_TAKRU	Vitellogenin domain-containing protein. (726 aa)
	LOC101073042	ATP-binding cassette, sub-family G (WHITE), member 4b. (634 aa)
	abcg5	ATP-binding cassette, sub-family G (WHITE), member 5. (643 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000074430	apoe2	ENSTRUP00000074430	ENSTRUP00000074375	annotation not available	Apolipoprotein E2.	0.768
ENSTRUP00000074430	npc2	ENSTRUP00000074430	ENSTRUP00000046752	annotation not available	Niemann-Pick disease, type C2.	0.589
ENSTRUP00000074430	scarb1	ENSTRUP00000074430	ENSTRUP00000071211	annotation not available	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.734
ENSTRUP00000084559	abcg5	ENSTRUP00000084559	ENSTRUP00000023704	ATP-binding cassette, subfamily G (WHITE), member 1.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.833
H2RM54_TAKRU	apoe2	ENSTRUP00000001217	ENSTRUP00000074375	Vitellogenin domain-containing protein.	Apolipoprotein E2.	0.768
H2RM54_TAKRU	npc2	ENSTRUP00000001217	ENSTRUP00000046752	Vitellogenin domain-containing protein.	Niemann-Pick disease, type C2.	0.589
H2RM54_TAKRU	scarb1	ENSTRUP00000001217	ENSTRUP00000071211	Vitellogenin domain-containing protein.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.734
LOC101066818	apoe2	ENSTRUP00000087964	ENSTRUP00000074375	Apolipoprotein Bb, tandem duplicate 2.	Apolipoprotein E2.	0.768
LOC101066818	npc2	ENSTRUP00000087964	ENSTRUP00000046752	Apolipoprotein Bb, tandem duplicate 2.	Niemann-Pick disease, type C2.	0.589
LOC101066818	scarb1	ENSTRUP00000087964	ENSTRUP00000071211	Apolipoprotein Bb, tandem duplicate 2.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.734
LOC101073042	abcg4	ENSTRUP00000010849	ENSTRUP00000087724	ATP-binding cassette, sub-family G (WHITE), member 4b.	ATP-binding cassette, sub-family G (WHITE), member 4a.	0.901
LOC101073042	abcg5	ENSTRUP00000010849	ENSTRUP00000023704	ATP-binding cassette, sub-family G (WHITE), member 4b.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.811
abcg4	LOC101073042	ENSTRUP00000087724	ENSTRUP00000010849	ATP-binding cassette, sub-family G (WHITE), member 4a.	ATP-binding cassette, sub-family G (WHITE), member 4b.	0.901
abcg4	abcg5	ENSTRUP00000087724	ENSTRUP00000023704	ATP-binding cassette, sub-family G (WHITE), member 4a.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.811
abcg5	ENSTRUP00000084559	ENSTRUP00000023704	ENSTRUP00000084559	ATP-binding cassette, sub-family G (WHITE), member 5.	ATP-binding cassette, subfamily G (WHITE), member 1.	0.833
abcg5	LOC101073042	ENSTRUP00000023704	ENSTRUP00000010849	ATP-binding cassette, sub-family G (WHITE), member 5.	ATP-binding cassette, sub-family G (WHITE), member 4b.	0.811
abcg5	abcg4	ENSTRUP00000023704	ENSTRUP00000087724	ATP-binding cassette, sub-family G (WHITE), member 5.	ATP-binding cassette, sub-family G (WHITE), member 4a.	0.811
abcg5	abcg8	ENSTRUP00000023704	ENSTRUP00000071734	ATP-binding cassette, sub-family G (WHITE), member 5.	ATP-binding cassette, sub-family G (WHITE), member 8.	0.999
abcg5	scarb1	ENSTRUP00000023704	ENSTRUP00000071211	ATP-binding cassette, sub-family G (WHITE), member 5.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.403
abcg8	abcg5	ENSTRUP00000071734	ENSTRUP00000023704	ATP-binding cassette, sub-family G (WHITE), member 8.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.999