STRINGSTRING
pdgfc pdgfc LOC101065472 LOC101065472 pdgfb pdgfb flt3 flt3 LOC101074548 LOC101074548 Pdgfd Pdgfd LOC101078824 LOC101078824 ENSTRUP00000061742 ENSTRUP00000061742 abl1 abl1 LOC101069599 LOC101069599 LOC101064414 LOC101064414 cspg4 cspg4 nrp1 nrp1 pdgfra pdgfra LOC101078573 LOC101078573 vegfa vegfa LOC101061306 LOC101061306 pdgfrb pdgfrb abl2 abl2 pdgfrl pdgfrl LOC101075610 LOC101075610 H2UFH2_TAKRU H2UFH2_TAKRU LOC101075732 LOC101075732 LOC101063539 LOC101063539 txnip txnip
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (342 aa)
LOC101065472Si:dkey-193c22.2. (2356 aa)
pdgfbPlatelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (542 aa)
flt3Fms-related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (984 aa)
LOC101074548Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b. (412 aa)
PdgfdPlatelet derived growth factor d; Belongs to the PDGF/VEGF growth factor family. (334 aa)
LOC101078824Sphingosine-1-phosphate lyase 1. (711 aa)
ENSTRUP00000061742AN1-type zinc finger protein 5-like isoform X1. (235 aa)
abl1Tyrosine-protein kinase. (1115 aa)
LOC101069599Uncharacterized protein. (222 aa)
LOC101064414Cysteine-serine-rich nuclear protein 1b. (546 aa)
cspg4Chondroitin sulfate proteoglycan 4. (2329 aa)
nrp1Neuropilin; Belongs to the neuropilin family. (955 aa)
pdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for pdgfa, pdgfb and pdgfc and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. Required for normal development of the gastrointestinal tract. Plays a role in cell migration and chemotaxis in wound [...] (1499 aa)
LOC101078573Zinc finger, AN1-type domain 5a. (285 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (218 aa)
LOC101061306Cysteine-serine-rich nuclear protein 1a. (562 aa)
pdgfrbPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Required for normal development of the cardiovascular system. Required for normal recruitment of [...] (1129 aa)
abl2Tyrosine-protein kinase. (1214 aa)
pdgfrlPlatelet-derived growth factor receptor-like. (370 aa)
LOC101075610Ig-like domain-containing protein. (386 aa)
H2UFH2_TAKRUStonin-1; May be involved in the endocytic machinery. (709 aa)
LOC101075732Uncharacterized protein LOC101075732 isoform X1. (505 aa)
LOC101063539Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (200 aa)
txnipThioredoxin interacting protein. (396 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.