(18 nodes) Regulation of antigen receptor-mediated signaling pathway network (Takifugu rubripes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sh2d1a	SH2 domain containing 1A duplicate b. (123 aa)
	rc3h1	Ring finger and CCCH-type domains 1b. (1123 aa)
	ENSTRUP00000062072	annotation not available (97 aa)
	LOC105417353	Signal-transducing adaptor protein 1 isoform X1. (371 aa)
	phpt1	Phosphohistidine phosphatase 1. (128 aa)
	cmtm3	CKLF-like MARVEL transmembrane domain containing 3. (204 aa)
	LOC101075763	Si:dkey-51e6.1. (125 aa)
	malt1	MALT paracaspase 1. (836 aa)
	LOC101069090	MALT paracaspase 2. (816 aa)
	cd226	CD226 molecule. (367 aa)
	LOC101072171	Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4. (543 aa)
	ENSTRUP00000031770	annotation not available (221 aa)
	card11	Uncharacterized protein. (1153 aa)
	ptprc	Uncharacterized protein. (1248 aa)
	slc39a6	Solute carrier family 39 member 6. (193 aa)
	LOC101070039	Solute carrier family 39 member 10. (957 aa)
	LOC105416219	MALT paracaspase 3. (589 aa)
	pawr	PRKC, apoptosis, WT1, regulator. (328 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000031770	cd226	ENSTRUP00000031770	ENSTRUP00000068382	annotation not available	CD226 molecule.	0.886
ENSTRUP00000062072	cd226	ENSTRUP00000062072	ENSTRUP00000068382	annotation not available	CD226 molecule.	0.405
LOC101069090	LOC105416219	ENSTRUP00000076686	ENSTRUP00000010990	MALT paracaspase 2.	MALT paracaspase 3.	0.906
LOC101069090	card11	ENSTRUP00000076686	ENSTRUP00000004660	MALT paracaspase 2.	Uncharacterized protein.	0.848
LOC101069090	malt1	ENSTRUP00000076686	ENSTRUP00000077782	MALT paracaspase 2.	MALT paracaspase 1.	0.903
LOC105416219	LOC101069090	ENSTRUP00000010990	ENSTRUP00000076686	MALT paracaspase 3.	MALT paracaspase 2.	0.906
LOC105416219	card11	ENSTRUP00000010990	ENSTRUP00000004660	MALT paracaspase 3.	Uncharacterized protein.	0.848
LOC105416219	malt1	ENSTRUP00000010990	ENSTRUP00000077782	MALT paracaspase 3.	MALT paracaspase 1.	0.902
card11	LOC101069090	ENSTRUP00000004660	ENSTRUP00000076686	Uncharacterized protein.	MALT paracaspase 2.	0.848
card11	LOC105416219	ENSTRUP00000004660	ENSTRUP00000010990	Uncharacterized protein.	MALT paracaspase 3.	0.848
card11	malt1	ENSTRUP00000004660	ENSTRUP00000077782	Uncharacterized protein.	MALT paracaspase 1.	0.848
cd226	ENSTRUP00000031770	ENSTRUP00000068382	ENSTRUP00000031770	CD226 molecule.	annotation not available	0.886
cd226	ENSTRUP00000062072	ENSTRUP00000068382	ENSTRUP00000062072	CD226 molecule.	annotation not available	0.405
malt1	LOC101069090	ENSTRUP00000077782	ENSTRUP00000076686	MALT paracaspase 1.	MALT paracaspase 2.	0.903
malt1	LOC105416219	ENSTRUP00000077782	ENSTRUP00000010990	MALT paracaspase 1.	MALT paracaspase 3.	0.902
malt1	card11	ENSTRUP00000077782	ENSTRUP00000004660	MALT paracaspase 1.	Uncharacterized protein.	0.848