(101 nodes) Maintenance of location network (Takifugu rubripes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tapt1	Transmembrane anterior posterior transformation 1b. (568 aa)
	ldah	Lipid droplet associated hydrolase. (320 aa)
	faf1	Fas (TNFRSF6) associated factor 1. (669 aa)
	LOC101078911	Uncharacterized protein. (1084 aa)
	LOC101071812	Si:ch211-11n16.2. (654 aa)
	vps13a	Uncharacterized protein. (3264 aa)
	LOC115250497	G_PROTEIN_RECEP_F1_2 domain-containing protein. (342 aa)
	ENSTRUP00000006769	annotation not available (448 aa)
	nrm	Nurim. (273 aa)
	H2S7F1_TAKRU	BSCL2 lipid droplet biogenesis associated, seipin. (421 aa)
	H2S9L9_TAKRU	UV radiation resistance associated gene. (658 aa)
	vps13c	Vacuolar protein sorting 13 homolog C. (3455 aa)
	cdk5	Cyclin-dependent kinase 5. (292 aa)
	arl2	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	charon	DAN related protein. (255 aa)
	nrros	Negative regulator of reactive oxygen species. (679 aa)
	pnpla2	Patatin-like phospholipase domain containing 2. (502 aa)
	aup1	AUP1 lipid droplet regulating VLDL assembly factor. (411 aa)
	LOC115247516	Un-named hu7912. (873 aa)
	pink1	PTEN induced kinase 1. (568 aa)
	LOC101076447	Fat storage inducing transmembrane protein 1, like. (285 aa)
	LOC101070744	Grancalcin. (337 aa)
	supt7l	SPT7 like, STAGA complex gamma subunit. (436 aa)
	LOC101063598	Patatin-like phospholipase domain containing 3. (471 aa)
	rnf213	Ring finger protein 213a. (5119 aa)
	LOC101072305	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (174 aa)
	H2UFI9_TAKRU	Thymosin beta 4 X-linked. (61 aa)
	insig2	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (207 aa)
	LOC101080082	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (454 aa)
	LOC101065347	PLA2c domain-containing protein. (326 aa)
	bard1	BRCA1 associated RING domain 1. (791 aa)
	gpsm2	Uncharacterized protein. (662 aa)
	LOC101072197	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (451 aa)
	ZFYVE1	Zinc finger FYVE-type containing 1. (787 aa)
	tbccd1	TBCC domain containing 1. (578 aa)
	il1b	Interleukin-1; Belongs to the IL-1 family. (256 aa)
	LOC101066257	ER lumen protein-retaining receptor. (212 aa)
	taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (930 aa)
	rangap1	Ran GTPase activating protein 1b. (577 aa)
	LOC101064499	Ankyrin repeat domain 13C. (685 aa)
	ENSTRUP00000044598	annotation not available (500 aa)
	LOC101068644	TPR_REGION domain-containing protein. (686 aa)
	angptl3	Angiopoietin-like 3. (469 aa)
	ciz1	Cdkn1a interacting zinc finger protein 1a. (751 aa)
	LOC105416602	G_PROTEIN_RECEP_F1_2 domain-containing protein. (342 aa)
	H2TYY9_TAKRU	Uncharacterized protein. (772 aa)
	fitm2	Fat storage inducing transmembrane protein 2. (277 aa)
	insig1	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (272 aa)
	spout1	SPOUT domain containing methyltransferase 1. (381 aa)
	ENSTRUP00000050578	Si:ch1073-303k11.2. (252 aa)
	LOC101068711	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (310 aa)
	Smim22	Uncharacterized protein. (120 aa)
	FITM1	Fat storage inducing transmembrane protein 1. (315 aa)
	cd4	T-cell surface glycoprotein CD4. (476 aa)
	ENSTRUP00000051898	PLAT domain-containing protein. (198 aa)
	psmd10	Proteasome 26S subunit, non-ATPase 10. (228 aa)
	polr2m	Uncharacterized protein. (270 aa)
	LOC101067583	BZIP domain-containing protein. (567 aa)
	b4galnt1	Beta-1,4 N-acetylgalactosaminyltransferase. (554 aa)
	arl2bp	ADP-ribosylation factor-like 2 binding protein. (178 aa)
	sufu	Suppressor of fused homolog. (483 aa)
	LOC101066788	Uncharacterized protein. (170 aa)
	ENSTRUP00000055319	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (71 aa)
	kdelr3	ER lumen protein-retaining receptor. (215 aa)
	ENSTRUP00000057255	Uncharacterized protein. (64 aa)
	tmem159	Uncharacterized protein. (169 aa)
	tspo	Translocator protein. (160 aa)
	ENSTRUP00000059731	annotation not available (310 aa)
	ENSTRUP00000060603	annotation not available (119 aa)
	LOC101069303	Transmembrane anterior posterior transformation 1a. (598 aa)
	igsf11	Immunoglobulin superfamily member 11. (479 aa)
	LOC101077818	Fibrinogen C-terminal domain-containing protein. (502 aa)
	LOC101065176	ER lumen protein-retaining receptor. (212 aa)
	rer1	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. (195 aa)
	ENSTRUP00000067845	RAN GTPase activating protein 1a. (567 aa)
	ENSTRUP00000069346	Fat storage inducing transmembrane protein 2. (277 aa)
	H2UNV5_TAKRU	Morc6_S5 domain-containing protein. (647 aa)
	LOC101073001	Twinfilin actin-binding protein 1a. (382 aa)
	gm2a	ML domain-containing protein. (355 aa)
	LOC115253298	SUN domain-containing protein 1-like. (342 aa)
	nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (318 aa)
	ENSTRUP00000075091	Cytosolic phospholipase A2 gamma-like. (545 aa)
	ENSTRUP00000075724	Fat storage inducing transmembrane protein 2. (277 aa)
	RANGAP1	RAN GTPase activating protein 1a. (576 aa)
	ENSTRUP00000077588	NRIP1_repr_2 domain-containing protein. (1078 aa)
	hexb	Beta-hexosaminidase. (565 aa)
	LOC101065843	ANK_REP_REGION domain-containing protein. (510 aa)
	vps13d	Vacuolar protein sorting 13 homolog D. (4378 aa)
	gopc	Golgi-associated PDZ and coiled-coil motif-containing protein isoform X1. (440 aa)
	sun2	SUN domain-containing protein. (469 aa)
	ENSTRUP00000081144	E3 ubiquitin-protein ligase rnf213-beta. (3579 aa)
	ENSTRUP00000081241	Patatin-like phospholipase domain-containing protein 2 isoform X1. (286 aa)
	ENSTRUP00000084486	annotation not available (361 aa)
	sorl1	Fibronectin type-III domain-containing protein. (2275 aa)
	bbs4	Bardet-Biedl syndrome 4. (564 aa)
	ENSTRUP00000085945	annotation not available (45 aa)
	apoa-i	Uncharacterized protein. (263 aa)
	golph3	Si:dkey-27b3.2. (293 aa)
	LOC101073484	Scinderin like b. (751 aa)
	hspa5	Heat shock protein 5; Belongs to the heat shock protein 70 family. (660 aa)
	arhgap21	Rho GTPase activating protein 21a. (2040 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000059731	il1b	ENSTRUP00000059731	ENSTRUP00000040920	annotation not available	Interleukin-1; Belongs to the IL-1 family.	0.505
ENSTRUP00000075091	LOC101065347	ENSTRUP00000075091	ENSTRUP00000037427	Cytosolic phospholipase A2 gamma-like.	PLA2c domain-containing protein.	0.903
ENSTRUP00000081241	LOC101063598	ENSTRUP00000081241	ENSTRUP00000024420	Patatin-like phospholipase domain-containing protein 2 isoform X1.	Patatin-like phospholipase domain containing 3.	0.903
ENSTRUP00000081241	pnpla2	ENSTRUP00000081241	ENSTRUP00000017351	Patatin-like phospholipase domain-containing protein 2 isoform X1.	Patatin-like phospholipase domain containing 2.	0.903
ENSTRUP00000084486	tmem159	ENSTRUP00000084486	ENSTRUP00000057390	annotation not available	Uncharacterized protein.	0.431
H2S7F1_TAKRU	tmem159	ENSTRUP00000008323	ENSTRUP00000057390	BSCL2 lipid droplet biogenesis associated, seipin.	Uncharacterized protein.	0.431
LOC101063598	ENSTRUP00000081241	ENSTRUP00000024420	ENSTRUP00000081241	Patatin-like phospholipase domain containing 3.	Patatin-like phospholipase domain-containing protein 2 isoform X1.	0.903
LOC101063598	pnpla2	ENSTRUP00000024420	ENSTRUP00000017351	Patatin-like phospholipase domain containing 3.	Patatin-like phospholipase domain containing 2.	0.903
LOC101065176	rer1	ENSTRUP00000065471	ENSTRUP00000067660	ER lumen protein-retaining receptor.	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.	0.437
LOC101065347	ENSTRUP00000075091	ENSTRUP00000037427	ENSTRUP00000075091	PLA2c domain-containing protein.	Cytosolic phospholipase A2 gamma-like.	0.903
LOC101066257	rer1	ENSTRUP00000040921	ENSTRUP00000067660	ER lumen protein-retaining receptor.	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.	0.437
LOC101068711	il1b	ENSTRUP00000050878	ENSTRUP00000040920	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.	Interleukin-1; Belongs to the IL-1 family.	0.505
LOC101068711	nfkbia	ENSTRUP00000050878	ENSTRUP00000073773	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.	0.903
LOC101069303	LOC101071812	ENSTRUP00000061134	ENSTRUP00000004967	Transmembrane anterior posterior transformation 1a.	Si:ch211-11n16.2.	0.444
LOC101069303	ZFYVE1	ENSTRUP00000061134	ENSTRUP00000038311	Transmembrane anterior posterior transformation 1a.	Zinc finger FYVE-type containing 1.	0.444
LOC101071812	LOC101069303	ENSTRUP00000004967	ENSTRUP00000061134	Si:ch211-11n16.2.	Transmembrane anterior posterior transformation 1a.	0.444
LOC101071812	ZFYVE1	ENSTRUP00000004967	ENSTRUP00000038311	Si:ch211-11n16.2.	Zinc finger FYVE-type containing 1.	0.902
LOC101071812	tapt1	ENSTRUP00000004967	ENSTRUP00000039871	Si:ch211-11n16.2.	Transmembrane anterior posterior transformation 1b.	0.444
LOC101072197	LOC101080082	ENSTRUP00000038196	ENSTRUP00000036902	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	0.901
LOC101072197	aup1	ENSTRUP00000038196	ENSTRUP00000018276	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	AUP1 lipid droplet regulating VLDL assembly factor.	0.431