(32 nodes) Convergent extension involved in gastrulation network (Takifugu rubripes)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	CDH2-2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (937 aa)
	desi2	Desumoylating isopeptidase 2. (217 aa)
	ENSTRUP00000086285	annotation not available (192 aa)
	LOC101063191	Tyrosine-protein kinase fyna. (554 aa)
	LOC101069639	Tyrosine-protein kinase. (537 aa)
	mcu	Mitochondrial calcium uniporter. (416 aa)
	CDH2	Cadherin 2. (925 aa)
	s1pr2	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (371 aa)
	LOC101069811	Growth differentiation factor 3. (388 aa)
	ofd1	OFD1 centriole and centriolar satellite protein. (985 aa)
	LOC101064562	Mothers against decapentaplegic homolog. (472 aa)
	ENSTRUP00000054254	annotation not available (337 aa)
	ENSTRUP00000050028	Leucine rich repeat containing 6. (405 aa)
	MCUB	Mitochondrial calcium uniporter dominant negative beta subunit. (339 aa)
	wnt5a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
	LOC101067574	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
	def6	DEF6 guanine nucleotide exchange factor a. (566 aa)
	lrrc1	Leucine rich repeat containing 1. (604 aa)
	LOC115246486	Tyrosyl-DNA phosphodiesterase 2b. (360 aa)
	LOC101065077	Tyrosyl-DNA phosphodiesterase 2 isoform X1. (360 aa)
	vangl2	Vang-like protein. (525 aa)
	TMEM216	Transmembrane protein 216. (143 aa)
	bmp2	Bone morphogenetic protein 2b. (420 aa)
	tab2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (748 aa)
	fyn	Tyrosine-protein kinase. (538 aa)
	setdb2	Uncharacterized protein. (591 aa)
	LOC101068730	VANGL planar cell polarity protein 2. (525 aa)
	LOC101065779	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (910 aa)
	YES1	Tyrosine-protein kinase. (549 aa)
	scrib	Scribble planar cell polarity protein. (1751 aa)
	chrd	Chordin. (962 aa)
	LOC101070204	Transmembrane protein 237b. (425 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2-2	LOC101065779	ENSTRUP00000067097	ENSTRUP00000066251	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.901
ENSTRUP00000054254	ENSTRUP00000086285	ENSTRUP00000054254	ENSTRUP00000086285	annotation not available	annotation not available	0.516
ENSTRUP00000086285	ENSTRUP00000054254	ENSTRUP00000086285	ENSTRUP00000054254	annotation not available	annotation not available	0.516
LOC101063191	LOC101069639	ENSTRUP00000063518	ENSTRUP00000059214	Tyrosine-protein kinase fyna.	Tyrosine-protein kinase.	0.940
LOC101063191	YES1	ENSTRUP00000063518	ENSTRUP00000069567	Tyrosine-protein kinase fyna.	Tyrosine-protein kinase.	0.940
LOC101064562	bmp2	ENSTRUP00000054551	ENSTRUP00000019830	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 2b.	0.750
LOC101064562	chrd	ENSTRUP00000054551	ENSTRUP00000073223	Mothers against decapentaplegic homolog.	Chordin.	0.474
LOC101065779	CDH2-2	ENSTRUP00000066251	ENSTRUP00000067097	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.901
LOC101067574	LOC101068730	ENSTRUP00000042225	ENSTRUP00000001525	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	VANGL planar cell polarity protein 2.	0.438
LOC101067574	vangl2	ENSTRUP00000042225	ENSTRUP00000024662	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Vang-like protein.	0.438
LOC101067574	wnt5a	ENSTRUP00000042225	ENSTRUP00000047995	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.902
LOC101068730	LOC101067574	ENSTRUP00000001525	ENSTRUP00000042225	VANGL planar cell polarity protein 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.438
LOC101068730	lrrc1	ENSTRUP00000001525	ENSTRUP00000038956	VANGL planar cell polarity protein 2.	Leucine rich repeat containing 1.	0.552
LOC101068730	scrib	ENSTRUP00000001525	ENSTRUP00000069749	VANGL planar cell polarity protein 2.	Scribble planar cell polarity protein.	0.552
LOC101068730	wnt5a	ENSTRUP00000001525	ENSTRUP00000047995	VANGL planar cell polarity protein 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.438
LOC101069639	LOC101063191	ENSTRUP00000059214	ENSTRUP00000063518	Tyrosine-protein kinase.	Tyrosine-protein kinase fyna.	0.940
LOC101069639	YES1	ENSTRUP00000059214	ENSTRUP00000069567	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
LOC101069639	fyn	ENSTRUP00000059214	ENSTRUP00000008304	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.426
LOC101069811	chrd	ENSTRUP00000056361	ENSTRUP00000073223	Growth differentiation factor 3.	Chordin.	0.423
LOC101070204	TMEM216	ENSTRUP00000087007	ENSTRUP00000021677	Transmembrane protein 237b.	Transmembrane protein 216.	0.568